119 related articles for article (PubMed ID: 15637051)
1. Gene trap mutagenesis-based forward genetic approach reveals that the tumor suppressor OVCA1 is a component of the biosynthetic pathway of diphthamide on elongation factor 2.
Nobukuni Y; Kohno K; Miyagawa K
J Biol Chem; 2005 Mar; 280(11):10572-7. PubMed ID: 15637051
[TBL] [Abstract][Full Text] [Related]
2. Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.
Liu S; Milne GT; Kuremsky JG; Fink GR; Leppla SH
Mol Cell Biol; 2004 Nov; 24(21):9487-97. PubMed ID: 15485916
[TBL] [Abstract][Full Text] [Related]
3. Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development.
Liu S; Bachran C; Gupta P; Miller-Randolph S; Wang H; Crown D; Zhang Y; Wein AN; Singh R; Fattah R; Leppla SH
Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13817-22. PubMed ID: 22869748
[TBL] [Abstract][Full Text] [Related]
4. Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins.
Liu S; Leppla SH
Mol Cell; 2003 Sep; 12(3):603-13. PubMed ID: 14527407
[TBL] [Abstract][Full Text] [Related]
5. OVCA1: tumor suppressor gene.
Chen CM; Behringer RR
Curr Opin Genet Dev; 2005 Feb; 15(1):49-54. PubMed ID: 15661533
[TBL] [Abstract][Full Text] [Related]
6. Characterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2.
Gupta PK; Liu S; Leppla SH
PLoS One; 2010 Feb; 5(2):e9078. PubMed ID: 20140093
[TBL] [Abstract][Full Text] [Related]
7. Influence of DPH1 and DPH5 Protein Variants on the Synthesis of Diphthamide, the Target of ADPRibosylating Toxins.
Mayer K; Schröder A; Schnitger J; Stahl S; Brinkmann U
Toxins (Basel); 2017 Feb; 9(3):. PubMed ID: 28245596
[TBL] [Abstract][Full Text] [Related]
8. Highly frequent single amino acid substitution in mammalian elongation factor 2 (EF-2) results in expression of resistance to EF-2-ADP-ribosylating toxins.
Kohno K; Uchida T
J Biol Chem; 1987 Sep; 262(25):12298-305. PubMed ID: 2887567
[TBL] [Abstract][Full Text] [Related]
9. Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
Foley BT; Moehring JM; Moehring TJ
J Biol Chem; 1995 Sep; 270(39):23218-25. PubMed ID: 7559470
[TBL] [Abstract][Full Text] [Related]
10. Site-specific mutagenesis of the histidine precursor of diphthamide in the human elongation factor-2 gene confers resistance to diphtheria toxin.
Ivankovic M; Rubelj I; Matulic M; Reich E; Brdar B
Mutat Res; 2006 Oct; 609(1):34-42. PubMed ID: 16901746
[TBL] [Abstract][Full Text] [Related]
11. Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome.
Yu YR; You LR; Yan YT; Chen CM
Hum Mol Genet; 2014 Nov; 23(21):5579-96. PubMed ID: 24895408
[TBL] [Abstract][Full Text] [Related]
12. Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells.
Bruening W; Prowse AH; Schultz DC; Holgado-Madruga M; Wong A; Godwin AK
Cancer Res; 1999 Oct; 59(19):4973-83. PubMed ID: 10519411
[TBL] [Abstract][Full Text] [Related]
13. Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis.
Chen CM; Behringer RR
Genes Dev; 2004 Feb; 18(3):320-32. PubMed ID: 14744934
[TBL] [Abstract][Full Text] [Related]
14. Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin.
Phan LD; Perentesis JP; Bodley JW
J Biol Chem; 1993 Apr; 268(12):8665-8. PubMed ID: 8473309
[TBL] [Abstract][Full Text] [Related]
15. Characterization of the endogenous ADP-ribosylation of wild-type and mutant elongation factor 2 in eukaryotic cells.
Fendrick JL; Iglewski WJ; Moehring JM; Moehring TJ
Eur J Biochem; 1992 Apr; 205(1):25-31. PubMed ID: 1313365
[TBL] [Abstract][Full Text] [Related]
16. Cloning, structure, and expression of the mouse Ovca1 gene.
Chen CM; Behringer RR
Biochem Biophys Res Commun; 2001 Sep; 286(5):1019-26. PubMed ID: 11527402
[TBL] [Abstract][Full Text] [Related]
17. A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin.
Roy V; Ghani K; Caruso M
PLoS One; 2010 Dec; 5(12):e15753. PubMed ID: 21203470
[TBL] [Abstract][Full Text] [Related]
18. In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin.
Moehring TJ; Danley DE; Moehring JM
Mol Cell Biol; 1984 Apr; 4(4):642-50. PubMed ID: 6717439
[TBL] [Abstract][Full Text] [Related]
19. A mutation in codon 717 of the CHO-K1 elongation factor 2 gene prevents the first step in the biosynthesis of diphthamide.
Foley BT; Moehring JM; Moehring TJ
Somat Cell Mol Genet; 1992 May; 18(3):227-31. PubMed ID: 1353910
[TBL] [Abstract][Full Text] [Related]
20. Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor.
Salicioni AM; Xi M; Vanderveer LA; Balsara B; Testa JR; Dunbrack RL; Godwin AK
Genomics; 2000 Oct; 69(1):54-62. PubMed ID: 11013075
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
