81 related articles for article (PubMed ID: 15637533)
1. Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer.
Boni JP; Leister C; Bender G; Fitzpatrick V; Twine N; Stover J; Dorner A; Immermann F; Burczynski ME
Clin Pharmacol Ther; 2005 Jan; 77(1):76-89. PubMed ID: 15637533
[TBL] [Abstract][Full Text] [Related]
2. Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer.
Raymond E; Alexandre J; Faivre S; Vera K; Materman E; Boni J; Leister C; Korth-Bradley J; Hanauske A; Armand JP
J Clin Oncol; 2004 Jun; 22(12):2336-47. PubMed ID: 15136596
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional profiles in peripheral blood mononuclear cells prognostic of clinical outcomes in patients with advanced renal cell carcinoma.
Burczynski ME; Twine NC; Dukart G; Marshall B; Hidalgo M; Stadler WM; Logan T; Dutcher J; Hudes G; Trepicchio WL; Strahs A; Immermann F; Slonim DK; Dorner AJ
Clin Cancer Res; 2005 Feb; 11(3):1181-9. PubMed ID: 15709187
[TBL] [Abstract][Full Text] [Related]
4. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma.
Atkins MB; Hidalgo M; Stadler WM; Logan TF; Dutcher JP; Hudes GR; Park Y; Liou SH; Marshall B; Boni JP; Dukart G; Sherman ML
J Clin Oncol; 2004 Mar; 22(5):909-18. PubMed ID: 14990647
[TBL] [Abstract][Full Text] [Related]
5. Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis.
Tejani A; Alexander S; Ettenger R; Lerner G; Zimmerman J; Kohaut E; Briscoe DM
Pediatr Transplant; 2004 Apr; 8(2):151-60. PubMed ID: 15049795
[TBL] [Abstract][Full Text] [Related]
6. A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer.
Hidalgo M; Buckner JC; Erlichman C; Pollack MS; Boni JP; Dukart G; Marshall B; Speicher L; Moore L; Rowinsky EK
Clin Cancer Res; 2006 Oct; 12(19):5755-63. PubMed ID: 17020981
[TBL] [Abstract][Full Text] [Related]
7. Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer.
Chan S; Scheulen ME; Johnston S; Mross K; Cardoso F; Dittrich C; Eiermann W; Hess D; Morant R; Semiglazov V; Borner M; Salzberg M; Ostapenko V; Illiger HJ; Behringer D; Bardy-Bouxin N; Boni J; Kong S; Cincotta M; Moore L
J Clin Oncol; 2005 Aug; 23(23):5314-22. PubMed ID: 15955899
[TBL] [Abstract][Full Text] [Related]
8. Comparison of temsirolimus pharmacokinetics in patients with renal cell carcinoma not receiving dialysis and those receiving hemodialysis: a case series.
Lunardi G; Armirotti A; Nicodemo M; Cavallini L; Damonte G; Vannozzi MO; Venturini M
Clin Ther; 2009 Aug; 31(8):1812-9. PubMed ID: 19808140
[TBL] [Abstract][Full Text] [Related]
9. Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies.
Mita MM; Mita AC; Chu QS; Rowinsky EK; Fetterly GJ; Goldston M; Patnaik A; Mathews L; Ricart AD; Mays T; Knowles H; Rivera VM; Kreisberg J; Bedrosian CL; Tolcher AW
J Clin Oncol; 2008 Jan; 26(3):361-7. PubMed ID: 18202410
[TBL] [Abstract][Full Text] [Related]
10. Pharmacokinetics of the immunosuppressant everolimus in maintenance renal transplant patients.
Budde K; Fritsche L; Waiser J; Glander P; Slowinski T; Neumayer HH;
Eur J Med Res; 2005 Apr; 10(4):169-74. PubMed ID: 15946913
[TBL] [Abstract][Full Text] [Related]
11. A comparison of measured trough levels and abbreviated AUC estimation by limited sampling strategies for monitoring mycophenolic acid exposure in stable heart transplant patients receiving cyclosporin A-containing and cyclosporin A-free immunosuppressive regimens.
Dösch AO; Ehlermann P; Koch A; Remppis A; Katus HA; Dengler TJ
Clin Ther; 2006 Jun; 28(6):893-905. PubMed ID: 16860172
[TBL] [Abstract][Full Text] [Related]
12. Phase I/II trial of temsirolimus combined with interferon alfa for advanced renal cell carcinoma.
Motzer RJ; Hudes GR; Curti BD; McDermott DF; Escudier BJ; Negrier S; Duclos B; Moore L; O'Toole T; Boni JP; Dutcher JP
J Clin Oncol; 2007 Sep; 25(25):3958-64. PubMed ID: 17761980
[TBL] [Abstract][Full Text] [Related]
13. Disposition of desipramine, a sensitive cytochrome P450 2D6 substrate, when coadministered with intravenous temsirolimus.
Boni J; Abbas R; Leister C; Burns J; Jordan R; Hoffmann M; DeMaio W; Hug B
Cancer Chemother Pharmacol; 2009 Jul; 64(2):263-70. PubMed ID: 19015855
[TBL] [Abstract][Full Text] [Related]
14. Pharmacokinetics and pharmacodynamics of epoetin delta in two studies in healthy volunteers and two studies in patients with chronic kidney disease.
Smith WB; Dowell JA; Pratt RD
Clin Ther; 2007 Jul; 29(7):1368-80. PubMed ID: 17825688
[TBL] [Abstract][Full Text] [Related]
15. CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
Margolin K; Longmate J; Baratta T; Synold T; Christensen S; Weber J; Gajewski T; Quirt I; Doroshow JH
Cancer; 2005 Sep; 104(5):1045-8. PubMed ID: 16007689
[TBL] [Abstract][Full Text] [Related]
16. Pharmacokinetic and pharmacodynamic assessments of the dipeptidyl peptidase-4 inhibitor PHX1149: double-blind, placebo-controlled, single- and multiple-dose studies in healthy subjects.
O'Farrell AM; van Vliet A; Abou Farha K; Cherrington JM; Campbell DA; Li X; Hanway D; Li J; Guler HP
Clin Ther; 2007 Aug; 29(8):1692-705. PubMed ID: 17919550
[TBL] [Abstract][Full Text] [Related]
17. A phase I multiple-dose escalation study characterizing pharmacokinetics and safety of ABT-578 in healthy subjects.
Karyekar CS; Pradhan RS; Freeney T; Ji Q; Edeki T; Chiu W; Awni WM; Locke C; Schwartz LB; Granneman RG; O'Dea R
J Clin Pharmacol; 2005 Aug; 45(8):910-8. PubMed ID: 16027401
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma.
Joerger M; Huitema AD; Meenhorst PL; Schellens JH; Beijnen JH
Cancer Chemother Pharmacol; 2005 May; 55(5):488-96. PubMed ID: 15726371
[TBL] [Abstract][Full Text] [Related]
19. Everolimus in pulmonary transplantation: pharmacokinetics and exposure-response relationships.
Kovarik JM; Snell GI; Valentine V; Aris R; Chan CK; Schmidli H; Pirron U
J Heart Lung Transplant; 2006 Apr; 25(4):440-6. PubMed ID: 16563975
[TBL] [Abstract][Full Text] [Related]
20. A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity.
Bocci G; Barbara C; Vannozzi F; Di Paolo A; Melosi A; Barsanti G; Allegrini G; Falcone A; Del Tacca M; Danesi R
Clin Pharmacol Ther; 2006 Oct; 80(4):384-95. PubMed ID: 17015056
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
