BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 15642371)

  • 1. Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia.
    Schnitzer SE; Schmid T; Zhou J; Eisenbrand G; Brüne B
    FEBS Lett; 2005 Jan; 579(2):529-33. PubMed ID: 15642371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.
    Mottet D; Dumont V; Deccache Y; Demazy C; Ninane N; Raes M; Michiels C
    J Biol Chem; 2003 Aug; 278(33):31277-85. PubMed ID: 12764143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
    Mabjeesh NJ; Willard MT; Frederickson CE; Zhong H; Simons JW
    Clin Cancer Res; 2003 Jul; 9(7):2416-25. PubMed ID: 12855613
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH; Wang YX; Bingle L; Gong LH; Heng WJ; Li Y; Fang WG
    J Pathol; 2005 Mar; 205(4):530-6. PubMed ID: 15714461
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
    Jiang BH; Jiang G; Zheng JZ; Lu Z; Hunter T; Vogt PK
    Cell Growth Differ; 2001 Jul; 12(7):363-9. PubMed ID: 11457733
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes.
    Moeller LC; Dumitrescu AM; Refetoff S
    Mol Endocrinol; 2005 Dec; 19(12):2955-63. PubMed ID: 16051672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway.
    Jin HO; An S; Lee HC; Woo SH; Seo SK; Choe TB; Yoo DH; Lee SB; Um HD; Lee SJ; Park MJ; Kim JI; Hong SI; Rhee CH; Park IC
    Cell Signal; 2007 Jul; 19(7):1393-403. PubMed ID: 17307335
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Estrogen-induced activation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor expression, and edema in the uterus are mediated by the phosphatidylinositol 3-kinase/Akt pathway.
    Kazi AA; Koos RD
    Endocrinology; 2007 May; 148(5):2363-74. PubMed ID: 17272396
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.
    Flügel D; Görlach A; Michiels C; Kietzmann T
    Mol Cell Biol; 2007 May; 27(9):3253-65. PubMed ID: 17325032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
    Tammali R; Saxena A; Srivastava SK; Ramana KV
    J Biol Chem; 2011 Jul; 286(27):24089-100. PubMed ID: 21576240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines.
    Box AH; Demetrick DJ
    Carcinogenesis; 2004 Dec; 25(12):2325-35. PubMed ID: 15347600
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional integrity of nuclear factor kappaB, phosphatidylinositol 3'-kinase, and mitogen-activated protein kinase signaling allows tumor necrosis factor alpha-evoked Bcl-2 expression to provoke internal ribosome entry site-dependent translation of hypoxia-inducible factor 1alpha.
    Zhou J; Callapina M; Goodall GJ; Brüne B
    Cancer Res; 2004 Dec; 64(24):9041-8. PubMed ID: 15604270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Wnt/beta-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1alpha.
    Jiang YG; Luo Y; He DL; Li X; Zhang LL; Peng T; Li MC; Lin YH
    Int J Urol; 2007 Nov; 14(11):1034-9. PubMed ID: 17956532
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition.
    McCarthy J; Lochner A; Opie LH; Sack MN; Essop MF
    J Cell Physiol; 2011 Sep; 226(9):2457-68. PubMed ID: 21660969
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N; Nester RA; Sarkar MA
    Toxicol Appl Pharmacol; 2004 Apr; 196(1):124-35. PubMed ID: 15050414
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1α and HIF2α stability and tumor growth, angiogenesis, and metastasis.
    Joshi S; Singh AR; Zulcic M; Durden DL
    Mol Cancer Res; 2014 Oct; 12(10):1520-31. PubMed ID: 25103499
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
    Laughner E; Taghavi P; Chiles K; Mahon PC; Semenza GL
    Mol Cell Biol; 2001 Jun; 21(12):3995-4004. PubMed ID: 11359907
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.