374 related articles for article (PubMed ID: 15646985)
1. Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.
Smith AB; Freeze BS; Lamarche MJ; Hirose T; Brouard I; Rucker PV; Xian M; Sundermann KF; Shaw SJ; Burlingame MA; Horwitz SB; Myles DC
Org Lett; 2005 Jan; 7(2):311-4. PubMed ID: 15646985
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C7 hydroxyl, and the lactone.
Smith AB; Xian M
Org Lett; 2005 Nov; 7(23):5229-32. PubMed ID: 16268545
[TBL] [Abstract][Full Text] [Related]
3. Design, total synthesis, and evaluation of C13-C14 cyclopropane analogues of (+)-discodermolide.
Smith AB; Xian M; Liu F
Org Lett; 2005 Oct; 7(21):4613-6. PubMed ID: 16209492
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide.
Smith AB; Freeze BS; Lamarche MJ; Hirose T; Brouard I; Xian M; Sundermann KF; Shaw SJ; Burlingame MA; Horwitz SB; Myles DC
Org Lett; 2005 Jan; 7(2):315-8. PubMed ID: 15646986
[TBL] [Abstract][Full Text] [Related]
5. Synthetic analogues of the microtubule-stabilizing agent (+)-discodermolide: preparation and biological activity.
Gunasekera SP; Mickel SJ; Daeffler R; Niederer D; Wright AE; Linley P; Pitts T
J Nat Prod; 2004 May; 67(5):749-56. PubMed ID: 15165132
[TBL] [Abstract][Full Text] [Related]
6. Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.
Florence GJ; Gardner NM; Paterson I
Nat Prod Rep; 2008 Apr; 25(2):342-75. PubMed ID: 18389141
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues.
Burlingame MA; Shaw SJ; Sundermann KF; Zhang D; Petryka J; Mendoza E; Liu F; Myles DC; LaMarche MJ; Hirose T; Scott Freeze B; Smith AB
Bioorg Med Chem Lett; 2004 May; 14(9):2335-8. PubMed ID: 15081036
[TBL] [Abstract][Full Text] [Related]
8. Total synthesis of the potent microtubule-stabilizing agent (+)-discodermolide.
Harried SS; Lee CP; Yang G; Lee TI; Myles DC
J Org Chem; 2003 Aug; 68(17):6646-60. PubMed ID: 12919029
[TBL] [Abstract][Full Text] [Related]
9. Toward understanding how the lactone moiety of discodermolide affects activity.
Shaw SJ; Sundermann KF; Burlingame MA; Myles DC; Freeze BS; Xian M; Brouard I; Smith AB
J Am Chem Soc; 2005 May; 127(18):6532-3. PubMed ID: 15869264
[TBL] [Abstract][Full Text] [Related]
10. Conception, synthesis, and biological evaluation of original discodermolide analogues.
de Lemos E; Agouridas E; Sorin G; Guerreiro A; Commerçon A; Pancrazi A; Betzer JF; Lannou MI; Ardisson J
Chemistry; 2011 Aug; 17(36):10123-34. PubMed ID: 21793059
[TBL] [Abstract][Full Text] [Related]
11. Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
Paterson I; Naylor GJ; Wright AE
Chem Commun (Camb); 2008 Oct; (38):4628-30. PubMed ID: 18815706
[TBL] [Abstract][Full Text] [Related]
12. Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.
Paterson I; Gardner NM; Guzmán E; Wright AE
Bioorg Med Chem Lett; 2008 Dec; 18(23):6268-72. PubMed ID: 18951787
[TBL] [Abstract][Full Text] [Related]
13. Semisynthetic analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.
Gunasekera SP; Longley RE; Isbrucker RA
J Nat Prod; 2002 Dec; 65(12):1830-7. PubMed ID: 12502323
[TBL] [Abstract][Full Text] [Related]
14. Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.
Paterson I; Naylor GJ; Fujita T; Guzmán E; Wright AE
Chem Commun (Camb); 2010 Jan; 46(2):261-3. PubMed ID: 20024345
[TBL] [Abstract][Full Text] [Related]
15. Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product--a further simplification of the lactone region.
Shaw SJ; Menzella HG; Myles DC; Xian M; Smith AB
Org Biomol Chem; 2007 Sep; 5(17):2753-5. PubMed ID: 17700839
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes.
Smith AB; Rucker PV; Brouard I; Freeze BS; Xia S; Horwitz SB
Org Lett; 2005 Nov; 7(23):5199-202. PubMed ID: 16268537
[TBL] [Abstract][Full Text] [Related]
17. Total synthesis of (+)-discodermolide: an improved endgame exploiting a Still-Gennari-type olefination with a C1-C8 beta-ketophosphonate fragment.
Paterson I; Lyothier I
Org Lett; 2004 Dec; 6(26):4933-6. PubMed ID: 15606103
[TBL] [Abstract][Full Text] [Related]
18. The structure activity relationship of discodermolide analogues.
Shaw SJ
Mini Rev Med Chem; 2008 Mar; 8(3):276-84. PubMed ID: 18336347
[TBL] [Abstract][Full Text] [Related]
19. Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
Paterson I; Naylor GJ; Gardner NM; Guzmán E; Wright AE
Chem Asian J; 2011 Feb; 6(2):459-73. PubMed ID: 21254424
[TBL] [Abstract][Full Text] [Related]
20. (+)-discodermolide: a marine natural product against cancer.
De Souza MV
ScientificWorldJournal; 2004 Jun; 4():415-36. PubMed ID: 15243683
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
