These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2. Sumi T; Matsumoto K; Takai Y; Nakamura T J Cell Biol; 1999 Dec; 147(7):1519-32. PubMed ID: 10613909 [TBL] [Abstract][Full Text] [Related]
3. Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase. Sumi T; Matsumoto K; Nakamura T J Biol Chem; 2001 Jan; 276(1):670-6. PubMed ID: 11018042 [TBL] [Abstract][Full Text] [Related]
4. Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA. Edlund S; Landström M; Heldin CH; Aspenström P Mol Biol Cell; 2002 Mar; 13(3):902-14. PubMed ID: 11907271 [TBL] [Abstract][Full Text] [Related]
5. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Maekawa M; Ishizaki T; Boku S; Watanabe N; Fujita A; Iwamatsu A; Obinata T; Ohashi K; Mizuno K; Narumiya S Science; 1999 Aug; 285(5429):895-8. PubMed ID: 10436159 [TBL] [Abstract][Full Text] [Related]
6. RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability. Clements RT; Minnear FL; Singer HA; Keller RS; Vincent PA Am J Physiol Lung Cell Mol Physiol; 2005 Feb; 288(2):L294-306. PubMed ID: 15475381 [TBL] [Abstract][Full Text] [Related]
7. Rho plays a key role in TGF-beta1-induced cytoskeletal rearrangement in human retinal pigment epithelium. Lee J; Ko M; Joo CK J Cell Physiol; 2008 Aug; 216(2):520-6. PubMed ID: 18314880 [TBL] [Abstract][Full Text] [Related]
8. LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. Amano T; Tanabe K; Eto T; Narumiya S; Mizuno K Biochem J; 2001 Feb; 354(Pt 1):149-59. PubMed ID: 11171090 [TBL] [Abstract][Full Text] [Related]
9. The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway. Ozawa T; Araki N; Yunoue S; Tokuo H; Feng L; Patrakitkomjorn S; Hara T; Ichikawa Y; Matsumoto K; Fujii K; Saya H J Biol Chem; 2005 Nov; 280(47):39524-33. PubMed ID: 16169856 [TBL] [Abstract][Full Text] [Related]
10. Regulation of myosin light chain function by BMP signaling controls actin cytoskeleton remodeling. Konstantinidis G; Moustakas A; Stournaras C Cell Physiol Biochem; 2011; 28(5):1031-44. PubMed ID: 22178953 [TBL] [Abstract][Full Text] [Related]
11. Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42. Edlund S; Landström M; Heldin CH; Aspenström P J Cell Sci; 2004 Apr; 117(Pt 9):1835-47. PubMed ID: 15075243 [TBL] [Abstract][Full Text] [Related]
12. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Yang N; Higuchi O; Ohashi K; Nagata K; Wada A; Kangawa K; Nishida E; Mizuno K Nature; 1998 Jun; 393(6687):809-12. PubMed ID: 9655398 [TBL] [Abstract][Full Text] [Related]
13. Multiple downstream signalling pathways from ROCK, a target molecule of Rho small G protein, in reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells. Takaishi K; Matozaki T; Nakano K; Takai Y Genes Cells; 2000 Nov; 5(11):929-936. PubMed ID: 11122380 [TBL] [Abstract][Full Text] [Related]
14. Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response. Thirone AC; Speight P; Zulys M; Rotstein OD; Szászi K; Pedersen SF; Kapus A Am J Physiol Cell Physiol; 2009 Mar; 296(3):C463-75. PubMed ID: 19109524 [TBL] [Abstract][Full Text] [Related]
15. Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway. Lee S; Helfman DM J Biol Chem; 2004 Jan; 279(3):1885-91. PubMed ID: 14559914 [TBL] [Abstract][Full Text] [Related]
16. Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation. Toshima J; Toshima JY; Amano T; Yang N; Narumiya S; Mizuno K Mol Biol Cell; 2001 Apr; 12(4):1131-45. PubMed ID: 11294912 [TBL] [Abstract][Full Text] [Related]
17. Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Ng J; Luo L Neuron; 2004 Dec; 44(5):779-93. PubMed ID: 15572110 [TBL] [Abstract][Full Text] [Related]
18. B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts. Pritchard CA; Hayes L; Wojnowski L; Zimmer A; Marais RM; Norman JC Mol Cell Biol; 2004 Jul; 24(13):5937-52. PubMed ID: 15199148 [TBL] [Abstract][Full Text] [Related]
19. LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics. Geneste O; Copeland JW; Treisman R J Cell Biol; 2002 May; 157(5):831-8. PubMed ID: 12034774 [TBL] [Abstract][Full Text] [Related]