BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 15649650)

  • 1. Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP?
    Kalivendi S; Hatakeyama K; Whitsett J; Konorev E; Kalyanaraman B; Vásquez-Vivar J
    Free Radic Biol Med; 2005 Feb; 38(4):481-91. PubMed ID: 15649650
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of human GTP cyclohydrolase I and its regulatory protein in tetrahydrobiopterin metabolism.
    Gesierich A; Niroomand F; Tiefenbacher CP
    Basic Res Cardiol; 2003 Mar; 98(2):69-75. PubMed ID: 12607127
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells.
    Shimizu S; Hiroi T; Ishii M; Hagiwara T; Wajima T; Miyazaki A; Kiuchi Y
    Int J Biochem Cell Biol; 2008; 40(4):755-65. PubMed ID: 18054268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GTP cyclohydrolase I mRNA is induced by LPS in vascular smooth muscle: characterization, sequence and relationship to nitric oxide synthase.
    Hattori Y; Gross SS
    Biochem Biophys Res Commun; 1993 Aug; 195(1):435-41. PubMed ID: 7689840
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GTP cyclohydrolase I feedback regulatory protein is expressed in serotonin neurons and regulates tetrahydrobiopterin biosynthesis.
    Kapatos G; Hirayama K; Shimoji M; Milstien S
    J Neurochem; 1999 Feb; 72(2):669-75. PubMed ID: 9930739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
    Tatham AL; Crabtree MJ; Warrick N; Cai S; Alp NJ; Channon KM
    J Biol Chem; 2009 May; 284(20):13660-13668. PubMed ID: 19286659
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.
    Li L; Rezvan A; Salerno JC; Husain A; Kwon K; Jo H; Harrison DG; Chen W
    Circ Res; 2010 Feb; 106(2):328-36. PubMed ID: 19926872
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
    Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
    Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Possible involvement of hydroxyl radical on the stimulation of tetrahydrobiopterin synthesis by hydrogen peroxide and peroxynitrite in vascular endothelial cells.
    Shimizu S; Ishii M; Miyasaka Y; Wajima T; Negoro T; Hagiwara T; Kiuchi Y
    Int J Biochem Cell Biol; 2005 Apr; 37(4):864-75. PubMed ID: 15694845
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
    Cai S; Khoo J; Channon KM
    Cardiovasc Res; 2005 Mar; 65(4):823-31. PubMed ID: 15721862
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduction of GTP cyclohydrolase I feedback regulating protein expression by hydrogen peroxide in vascular endothelial cells.
    Ishii M; Shimizu S; Wajima T; Hagiwara T; Negoro T; Miyazaki A; Tobe T; Kiuchi Y
    J Pharmacol Sci; 2005 Feb; 97(2):299-302. PubMed ID: 15699573
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA.
    Schwartz IF; Schwartz D; Wollman Y; Chernichowski T; Blum M; Levo Y; Iaina A
    J Lab Clin Med; 2001 May; 137(5):356-62. PubMed ID: 11329533
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein.
    Xie L; Smith JA; Gross SS
    J Biol Chem; 1998 Aug; 273(33):21091-8. PubMed ID: 9694862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3.
    Huang A; Zhang YY; Chen K; Hatakeyama K; Keaney JF
    Circ Res; 2005 Feb; 96(2):164-71. PubMed ID: 15604419
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oral administration of tetrahydrobiopterin attenuates testicular damage by reducing nitric oxide synthase activity in a cryptorchid mouse model.
    Kondo Y; Ishikawa T; Yamaguchi K; Yada T; Fujisawa M
    J Androl; 2008; 29(2):153-63. PubMed ID: 17978343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ligand binding to the inhibitory and stimulatory GTP cyclohydrolase I/GTP cyclohydrolase I feedback regulatory protein complexes.
    Yoneyama T; Hatakeyama K
    Protein Sci; 2001 Apr; 10(4):871-8. PubMed ID: 11274478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP.
    Milstien S; Jaffe H; Kowlessur D; Bonner TI
    J Biol Chem; 1996 Aug; 271(33):19743-51. PubMed ID: 8702680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats.
    Meininger CJ; Cai S; Parker JL; Channon KM; Kelly KA; Becker EJ; Wood MK; Wade LA; Wu G
    FASEB J; 2004 Dec; 18(15):1900-2. PubMed ID: 15467010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
    Shimizu S; Shiota K; Yamamoto S; Miyasaka Y; Ishii M; Watabe T; Nishida M; Mori Y; Yamamoto T; Kiuchi Y
    Free Radic Biol Med; 2003 May; 34(10):1343-52. PubMed ID: 12726922
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP.
    Higgins CE; Gross SS
    J Biol Chem; 2011 Apr; 286(14):11919-28. PubMed ID: 21163945
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.