BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 15649899)

  • 1. Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.
    Shi Q; Chen HL; Xu H; Gibson GE
    J Biol Chem; 2005 Mar; 280(12):10888-96. PubMed ID: 15649899
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease.
    Shi Q; Xu H; Kleinman WA; Gibson GE
    Biochim Biophys Acta; 2008 Apr; 1782(4):229-38. PubMed ID: 18206986
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.
    Shi Q; Karuppagounder SS; Xu H; Pechman D; Chen H; Gibson GE
    Neurochem Int; 2007 Jun; 50(7-8):921-31. PubMed ID: 17482317
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease.
    Sheu KF; Cooper AJ; Koike K; Koike M; Lindsay JG; Blass JP
    Ann Neurol; 1994 Mar; 35(3):312-8. PubMed ID: 8122883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alpha-ketoglutarate dehydrogenase in Alzheimer brains bearing the APP670/671 mutation.
    Gibson GE; Zhang H; Sheu KF; Bogdanovich N; Lindsay JG; Lannfelt L; Vestling M; Cowburn RF
    Ann Neurol; 1998 Oct; 44(4):676-81. PubMed ID: 9778267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines.
    Gibson GE; Xu H; Chen HL; Chen W; Denton TT; Zhang S
    J Neurochem; 2015 Jul; 134(1):86-96. PubMed ID: 25772995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex.
    Shi Q; Xu H; Yu H; Zhang N; Ye Y; Estevez AG; Deng H; Gibson GE
    J Biol Chem; 2011 May; 286(20):17640-8. PubMed ID: 21454586
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?
    Chen H; Denton TT; Xu H; Calingasan N; Beal MF; Gibson GE
    J Neurochem; 2016 Dec; 139(5):823-838. PubMed ID: 27580471
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases.
    Calingasan NY; Ho DJ; Wille EJ; Campagna MV; Ruan J; Dumont M; Yang L; Shi Q; Gibson GE; Beal MF
    Neuroscience; 2008 Jun; 153(4):986-96. PubMed ID: 18423880
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The influence of 5-fluorouracil on the α-ketoglutarate dehydrogenase complex in rat's cardiac muscle - a preliminary study.
    Knapik-Czajka M; Gawędzka A; Jurczyk M; Drąg J; Belczyk M; Aleksanrovych V; Gil A; Gil K
    Folia Med Cracov; 2022; 62(2):27-35. PubMed ID: 36256893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ.
    Zündorf G; Kahlert S; Bunik VI; Reiser G
    Neuroscience; 2009 Jan; 158(2):610-6. PubMed ID: 18996448
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation.
    Dobolyi A; Bago A; Palkovits M; Nemeria NS; Jordan F; Doczi J; Ambrus A; Adam-Vizi V; Chinopoulos C
    Brain Struct Funct; 2020 Mar; 225(2):639-667. PubMed ID: 31982949
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isolation, characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of human alpha-ketoglutarate dehydrogenase complex.
    Ali G; Wasco W; Cai X; Szabo P; Sheu KF; Cooper AJ; Gaston SM; Gusella JF; Tanzi RE; Blass JP
    Somat Cell Mol Genet; 1994 Mar; 20(2):99-105. PubMed ID: 8009371
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration.
    Gibson GE; Blass JP; Beal MF; Bunik V
    Mol Neurobiol; 2005; 31(1-3):43-63. PubMed ID: 15953811
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Brain [U-13 C]glucose metabolism in mice with decreased α-ketoglutarate dehydrogenase complex activity.
    Nilsen LH; Shi Q; Gibson GE; Sonnewald U
    J Neurosci Res; 2011 Dec; 89(12):1997-2007. PubMed ID: 21374701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.
    Ambrus A; Tretter L; Adam-Vizi V
    J Neurochem; 2009 May; 109 Suppl 1():222-9. PubMed ID: 19393031
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.
    Starkov AA; Fiskum G; Chinopoulos C; Lorenzo BJ; Browne SE; Patel MS; Beal MF
    J Neurosci; 2004 Sep; 24(36):7779-88. PubMed ID: 15356189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Independent modulation of the activity of alpha-ketoglutarate dehydrogenase complex by Ca2+ and Mg2+.
    Panov A; Scarpa A
    Biochemistry; 1996 Jan; 35(2):427-32. PubMed ID: 8555212
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis.
    Shi Q; Risa Ø; Sonnewald U; Gibson GE
    J Neurochem; 2009 May; 109 Suppl 1(Suppl 1):214-21. PubMed ID: 19393030
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells.
    Bunik VI; Denton TT; Xu H; Thompson CM; Cooper AJ; Gibson GE
    Biochemistry; 2005 Aug; 44(31):10552-61. PubMed ID: 16060664
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.