316 related articles for article (PubMed ID: 15664989)
1. Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.
Jana NR; Dikshit P; Goswami A; Kotliarova S; Murata S; Tanaka K; Nukina N
J Biol Chem; 2005 Mar; 280(12):11635-40. PubMed ID: 15664989
[TBL] [Abstract][Full Text] [Related]
2. CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.
Al-Ramahi I; Lam YC; Chen HK; de Gouyon B; Zhang M; Pérez AM; Branco J; de Haro M; Patterson C; Zoghbi HY; Botas J
J Biol Chem; 2006 Sep; 281(36):26714-24. PubMed ID: 16831871
[TBL] [Abstract][Full Text] [Related]
3. Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity.
Chhangani D; Nukina N; Kurosawa M; Amanullah A; Joshi V; Upadhyay A; Mishra A
Biochim Biophys Acta; 2014 Sep; 1842(9):1472-84. PubMed ID: 24769000
[TBL] [Abstract][Full Text] [Related]
4. Co-chaperone CHIP promotes aggregation of ataxin-1.
Choi JY; Ryu JH; Kim HS; Park SG; Bae KH; Kang S; Myung PK; Cho S; Park BC; Lee DH
Mol Cell Neurosci; 2007 Jan; 34(1):69-79. PubMed ID: 17127076
[TBL] [Abstract][Full Text] [Related]
5. [Involvement of ubiquitin-proteasome system in polyglutamine disease].
Matsumoto M
Tanpakushitsu Kakusan Koso; 2006 Aug; 51(10 Suppl):1428-32. PubMed ID: 16922413
[No Abstract] [Full Text] [Related]
6. Misfolding promotes the ubiquitination of polyglutamine-expanded ataxin-3, the defective gene product in SCA3/MJD.
Jana NR; Nukina N
Neurotox Res; 2004; 6(7-8):523-33. PubMed ID: 15639784
[TBL] [Abstract][Full Text] [Related]
7. In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis.
Williams AJ; Knutson TM; Colomer Gould VF; Paulson HL
Neurobiol Dis; 2009 Mar; 33(3):342-53. PubMed ID: 19084066
[TBL] [Abstract][Full Text] [Related]
8. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.
Jana NR; Tanaka M; Wang Gh; Nukina N
Hum Mol Genet; 2000 Aug; 9(13):2009-18. PubMed ID: 10942430
[TBL] [Abstract][Full Text] [Related]
9. Promyelocytic leukemia protein is redistributed during the formation of intranuclear inclusions independent of polyglutamine expansion: an immunohistochemical study on Marinesco bodies.
Kumada S; Uchihara T; Hayashi M; Nakamura A; Kikuchi E; Mizutani T; Oda M
J Neuropathol Exp Neurol; 2002 Nov; 61(11):984-91. PubMed ID: 12430715
[TBL] [Abstract][Full Text] [Related]
10. Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones.
Rousseau E; Kojima R; Hoffner G; Djian P; Bertolotti A
J Biol Chem; 2009 Jan; 284(3):1917-29. PubMed ID: 18986984
[TBL] [Abstract][Full Text] [Related]
11. Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin-3.
Berke SJ; Chai Y; Marrs GL; Wen H; Paulson HL
J Biol Chem; 2005 Sep; 280(36):32026-34. PubMed ID: 16040601
[TBL] [Abstract][Full Text] [Related]
12. Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity.
Kvam E; Nannenga BL; Wang MS; Jia Z; Sierks MR; Messer A
PLoS One; 2009 May; 4(5):e5727. PubMed ID: 19492089
[TBL] [Abstract][Full Text] [Related]
13. Inefficient degradation of truncated polyglutamine proteins by the proteasome.
Holmberg CI; Staniszewski KE; Mensah KN; Matouschek A; Morimoto RI
EMBO J; 2004 Oct; 23(21):4307-18. PubMed ID: 15470501
[TBL] [Abstract][Full Text] [Related]
14. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
Jana NR; Zemskov EA; Wang Gh ; Nukina N
Hum Mol Genet; 2001 May; 10(10):1049-59. PubMed ID: 11331615
[TBL] [Abstract][Full Text] [Related]
15. Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.
Chai Y; Koppenhafer SL; Shoesmith SJ; Perez MK; Paulson HL
Hum Mol Genet; 1999 Apr; 8(4):673-82. PubMed ID: 10072437
[TBL] [Abstract][Full Text] [Related]
16. p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome.
Wang H; Jia N; Fei E; Wang Z; Liu C; Zhang T; Fan J; Wu M; Chen L; Nukina N; Zhou J; Wang G
J Neurochem; 2007 Jun; 101(6):1651-61. PubMed ID: 17302910
[TBL] [Abstract][Full Text] [Related]
17. Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins.
Chhangani D; Upadhyay A; Amanullah A; Joshi V; Mishra A
Sci Rep; 2014 May; 4():5077. PubMed ID: 24865853
[TBL] [Abstract][Full Text] [Related]
18. H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
Wang HL; Hu SH; Chou AH; Wang SS; Weng YH; Yeh TH
Neuropharmacology; 2013 Jul; 70():1-11. PubMed ID: 23347954
[TBL] [Abstract][Full Text] [Related]
19. [Mechanisms to control degradation of polyglutamine-containing protein].
Nakayama K
Rinsho Shinkeigaku; 2003 Nov; 43(11):906-8. PubMed ID: 15152500
[TBL] [Abstract][Full Text] [Related]
20. Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways.
Chai Y; Berke SS; Cohen RE; Paulson HL
J Biol Chem; 2004 Jan; 279(5):3605-11. PubMed ID: 14602712
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
