BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 15670914)

  • 21. Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerases I and II.
    Yonezawa Y; Tsuzuki T; Eitsuka T; Miyazawa T; Hada T; Uryu K; Murakami-Nakai C; Ikawa H; Kuriyama I; Takemura M; Oshige M; Yoshida H; Sakaguchi K; Mizushina Y
    Arch Biochem Biophys; 2005 Mar; 435(1):197-206. PubMed ID: 15680922
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 3D-QSAR analysis on benzazole derivatives as eukaryotic topoisomerase II inhibitors by using comparative molecular field analysis method.
    Temiz-Arpaci O; Tekiner-Gulbas B; Yildiz I; Aki-Sener E; Yalcin I
    Bioorg Med Chem; 2005 Dec; 13(23):6354-9. PubMed ID: 15993083
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Antitumour drug design: DNA-binding ligands, which inhibit the topoisomerase I.
    Pindur U; Lemster T
    Pharmazie; 1998 Feb; 53(2):79-86. PubMed ID: 9540103
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DNA topoisomerase I inhibitory alkaloids from Corydalis saxicola.
    Cheng X; Wang D; Jiang L; Yang D
    Chem Biodivers; 2008 Jul; 5(7):1335-44. PubMed ID: 18649321
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A three-dimensional quantitative structure-activity analysis of a new class of bisphenol topoisomerase IIalpha inhibitors.
    Liang H; Wu X; Yalowich JC; Hasinoff BB
    Mol Pharmacol; 2008 Mar; 73(3):686-96. PubMed ID: 18045852
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and topoisomerase poisoning activity of A-ring and E-ring substituted luotonin A derivatives.
    Nacro K; Zha CC; Guzzo PR; Jason Herr R; Peace D; Friedrich TD
    Bioorg Med Chem; 2007 Jun; 15(12):4237-46. PubMed ID: 17418582
    [TBL] [Abstract][Full Text] [Related]  

  • 27. New carbocyclic lexitropsins with dinitromustard as N-terminal fragment. Inhibition of topoisomerases.
    Markowska A; Bielawska A; Bielawski K; Midura-Nowaczek K
    Acta Pol Pharm; 2003; 60(2):119-21. PubMed ID: 13678319
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.
    Mizushina Y; Akihisa T; Ukiya M; Hamasaki Y; Murakami-Nakai C; Kuriyama I; Takeuchi T; Sugawara F; Yoshida H
    Life Sci; 2005 Sep; 77(17):2127-40. PubMed ID: 15935396
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S; Vandenberghe I; Robin M; Annereau JP; Créancier L; Pique V; Galy JP; Kruczynski A; Barret JM; Bailly C
    Biochem Pharmacol; 2007 Jun; 73(12):1863-72. PubMed ID: 17391647
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Dual inhibition of DNA topoisomerases of Leishmania donovani by novel indolyl quinolines.
    Ray S; Sadhukhan PK; Mandal NB; Mahato SB; Majumder HK
    Biochem Biophys Res Commun; 1997 Jan; 230(1):171-5. PubMed ID: 9020039
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A tale of two tumor targets: topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy.
    Cragg GM; Newman DJ
    J Nat Prod; 2004 Feb; 67(2):232-44. PubMed ID: 14987065
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution.
    Todd AK; Adams A; Thorpe JH; Denny WA; Wakelin LP; Cardin CJ
    J Med Chem; 1999 Feb; 42(4):536-40. PubMed ID: 10052960
    [No Abstract]   [Full Text] [Related]  

  • 33. Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity.
    Choi SJ; Park HJ; Lee SK; Kim SW; Han G; Choo HY
    Bioorg Med Chem; 2006 Feb; 14(4):1229-35. PubMed ID: 16242334
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Topoisomerase I and II inhibitory constituents from the bark of Tilia amurensis.
    Choi JY; Seo CS; Zheng MS; Lee CS; Son JK
    Arch Pharm Res; 2008 Nov; 31(11):1413-8. PubMed ID: 19023537
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Novel synthetic isoquinolino[5,4-ab]phenazines: inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities.
    Yang P; Yang Q; Qian X; Cui J
    Bioorg Med Chem; 2005 Nov; 13(21):5909-14. PubMed ID: 16115776
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 14-azacamptothecin: a potent water-soluble topoisomerase I poison.
    Cheng K; Rahier NJ; Eisenhauer BM; Gao R; Thomas SJ; Hecht SM
    J Am Chem Soc; 2005 Jan; 127(3):838-9. PubMed ID: 15656613
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.
    Ahn G; Schifano-Faux N; Goossens JF; Baldeyrou B; Couture A; Grandclaudon P; Lansiaux A; Ryckebusch A
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2259-63. PubMed ID: 21439821
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogs.
    Wang BB; Maghami N; Goodlin VL; Smith PJ
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3221-6. PubMed ID: 15149679
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis of 6-chloroisoquinoline-5,8-diones and pyrido[3,4-b]phenazine-5,12-diones and evaluation of their cytotoxicity and DNA topoisomerase II inhibitory activity.
    Kim JS; Rhee HK; Park HJ; Lee IK; Lee SK; Suh ME; Lee HJ; Ryu CK; Choo HY
    Bioorg Med Chem; 2007 Jan; 15(1):451-7. PubMed ID: 17035025
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Convenient synthesis of indeno[1,2-c]isoquinolines as constrained forms of 3-arylisoquinolines and docking study of a topoisomerase I inhibitor into DNA-topoisomerase I complex.
    Van HT; Le QM; Lee KY; Lee ES; Kwon Y; Kim TS; Le TN; Lee SH; Cho WJ
    Bioorg Med Chem Lett; 2007 Nov; 17(21):5763-7. PubMed ID: 17827007
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.