BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 15671247)

  • 1. AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.
    Felekkis KN; Narsimhan RP; Near R; Castro AF; Zheng Y; Quilliam LA; Lerner A
    Mol Cancer Res; 2005 Jan; 3(1):32-41. PubMed ID: 15671247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
    Stoica GE; Franke TF; Wellstein A; Czubayko F; List HJ; Reiter R; Morgan E; Martin MB; Stoica A
    Mol Endocrinol; 2003 May; 17(5):818-30. PubMed ID: 12554767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.
    Cai D; Iyer A; Felekkis KN; Near RI; Luo Z; Chernoff J; Albanese C; Pestell RG; Lerner A
    Cancer Res; 2003 Oct; 63(20):6802-8. PubMed ID: 14583477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.
    Campbell RA; Bhat-Nakshatri P; Patel NM; Constantinidou D; Ali S; Nakshatri H
    J Biol Chem; 2001 Mar; 276(13):9817-24. PubMed ID: 11139588
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.
    Stoica GE; Franke TF; Moroni M; Mueller S; Morgan E; Iann MC; Winder AD; Reiter R; Wellstein A; Martin MB; Stoica A
    Oncogene; 2003 Sep; 22(39):7998-8011. PubMed ID: 12970748
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines.
    Kimura A; Ohmichi M; Kawagoe J; Kyo S; Mabuchi S; Takahashi T; Ohshima C; Arimoto-Ishida E; Nishio Y; Inoue M; Kurachi H; Tasaka K; Murata Y
    Oncogene; 2004 Jun; 23(26):4505-15. PubMed ID: 15048073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rac is activated by erythropoietin or interleukin-3 and is involved in activation of the Erk signaling pathway.
    Arai A; Kanda E; Miura O
    Oncogene; 2002 Apr; 21(17):2641-51. PubMed ID: 11965537
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation.
    Pozo-Guisado E; Lorenzo-Benayas MJ; Fernández-Salguero PM
    Int J Cancer; 2004 Mar; 109(2):167-73. PubMed ID: 14750165
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.
    Sun M; Paciga JE; Feldman RI; Yuan Z; Coppola D; Lu YY; Shelley SA; Nicosia SV; Cheng JQ
    Cancer Res; 2001 Aug; 61(16):5985-91. PubMed ID: 11507039
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitogenic activity of estrogens in human breast cancer cells does not rely on direct induction of mitogen-activated protein kinase/extracellularly regulated kinase or phosphatidylinositol 3-kinase.
    Gaben AM; Saucier C; Bedin M; Redeuilh G; Mester J
    Mol Endocrinol; 2004 Nov; 18(11):2700-13. PubMed ID: 15297603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. R-Ras3, a brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells.
    Kimmelman AC; Osada M; Chan AM
    Oncogene; 2000 Apr; 19(16):2014-22. PubMed ID: 10803462
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes.
    Genot E; Reif K; Beach S; Kramer I; Cantrell D
    Oncogene; 1998 Oct; 17(13):1731-8. PubMed ID: 9796702
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
    Nosaka Y; Arai A; Kanda E; Akasaki T; Sumimoto H; Miyasaka N; Miura O
    Biochem Biophys Res Commun; 2001 Jul; 285(3):675-9. PubMed ID: 11453646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling.
    Varma H; Conrad SE
    Cancer Res; 2002 Jul; 62(14):3985-91. PubMed ID: 12124331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA; Park MT; Kang CM; Um HD; Bae S; Lee KH; Kim TH; Kim JH; Cho CK; Lee YS; Chung HY; Lee SJ
    Oncogene; 2004 Jan; 23(1):9-20. PubMed ID: 14712206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.
    Gotoh T; Cai D; Tian X; Feig LA; Lerner A
    J Biol Chem; 2000 Sep; 275(39):30118-23. PubMed ID: 10896938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras.
    Akagi T; Murata K; Shishido T; Hanafusa H
    Mol Cell Biol; 2002 Oct; 22(20):7015-23. PubMed ID: 12242282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 17 beta-estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells.
    Guo RX; Wei LH; Tu Z; Sun PM; Wang JL; Zhao D; Li XP; Tang JM
    J Steroid Biochem Mol Biol; 2006 Apr; 99(1):9-18. PubMed ID: 16567092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.
    Han J; Luby-Phelps K; Das B; Shu X; Xia Y; Mosteller RD; Krishna UM; Falck JR; White MA; Broek D
    Science; 1998 Jan; 279(5350):558-60. PubMed ID: 9438848
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M; Morelli C; Mauro L; Andò S; Surmacz E
    Cancer Res; 2001 Sep; 61(18):6747-54. PubMed ID: 11559546
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.