BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

375 related articles for article (PubMed ID: 15677476)

  • 21. Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint.
    Kühne C; Tjörnhammar ML; Pongor S; Banks L; Simoncsits A
    Nucleic Acids Res; 2003 Dec; 31(24):7227-37. PubMed ID: 14654698
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks.
    Dong J; Zhang T; Ren Y; Wang Z; Ling CC; He F; Li GC; Wang C; Wen B
    Oncotarget; 2017 Apr; 8(14):22662-22673. PubMed ID: 28186989
    [TBL] [Abstract][Full Text] [Related]  

  • 23. TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1.
    Zou LH; Shang ZF; Tan W; Liu XD; Xu QZ; Song M; Wang Y; Guan H; Zhang SM; Yu L; Zhong CG; Zhou PK
    Oncotarget; 2015 Mar; 6(9):7011-22. PubMed ID: 25749521
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DNA-PKcs-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks.
    Lu H; Guan J; Wang SY; Li GM; Bohr VA; Davis AJ
    Nucleic Acids Res; 2022 Jun; 50(10):5635-5651. PubMed ID: 35580045
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends.
    Reddy YV; Ding Q; Lees-Miller SP; Meek K; Ramsden DA
    J Biol Chem; 2004 Sep; 279(38):39408-13. PubMed ID: 15258142
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.
    Toulany M; Lee KJ; Fattah KR; Lin YF; Fehrenbacher B; Schaller M; Chen BP; Chen DJ; Rodemann HP
    Mol Cancer Res; 2012 Jul; 10(7):945-57. PubMed ID: 22596249
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
    Jin S; Weaver DT
    EMBO J; 1997 Nov; 16(22):6874-85. PubMed ID: 9362500
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
    Calsou P; Delteil C; Frit P; Drouet J; Salles B
    J Mol Biol; 2003 Feb; 326(1):93-103. PubMed ID: 12547193
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence.
    Liu Y; Efimova EV; Ramamurthy A; Kron SJ
    J Cell Sci; 2019 Jul; 132(13):. PubMed ID: 31189537
    [TBL] [Abstract][Full Text] [Related]  

  • 30. BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle.
    Davis AJ; Chi L; So S; Lee KJ; Mori E; Fattah K; Yang J; Chen DJ
    Nucleic Acids Res; 2014 Oct; 42(18):11487-501. PubMed ID: 25223785
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs).
    Convery E; Shin EK; Ding Q; Wang W; Douglas P; Davis LS; Nickoloff JA; Lees-Miller SP; Meek K
    Proc Natl Acad Sci U S A; 2005 Feb; 102(5):1345-50. PubMed ID: 15668400
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation.
    Dobbs TA; Tainer JA; Lees-Miller SP
    DNA Repair (Amst); 2010 Dec; 9(12):1307-14. PubMed ID: 21030321
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis.
    Douglas P; Ye R; Trinkle-Mulcahy L; Neal JA; De Wever V; Morrice NA; Meek K; Lees-Miller SP
    Biosci Rep; 2014 Jun; 34(3):. PubMed ID: 24844881
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs.
    Boskovic J; Rivera-Calzada A; Maman JD; Chacón P; Willison KR; Pearl LH; Llorca O
    EMBO J; 2003 Nov; 22(21):5875-82. PubMed ID: 14592984
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts.
    Povirk LF; Zhou RZ; Ramsden DA; Lees-Miller SP; Valerie K
    Nucleic Acids Res; 2007; 35(12):3869-78. PubMed ID: 17526517
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Interactive competition between homologous recombination and non-homologous end joining.
    Allen C; Halbrook J; Nickoloff JA
    Mol Cancer Res; 2003 Oct; 1(12):913-20. PubMed ID: 14573792
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.
    Chen BP; Uematsu N; Kobayashi J; Lerenthal Y; Krempler A; Yajima H; Löbrich M; Shiloh Y; Chen DJ
    J Biol Chem; 2007 Mar; 282(9):6582-7. PubMed ID: 17189255
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.
    Ader I; Muller C; Bonnet J; Favre G; Cohen-Jonathan E; Salles B; Toulas C
    Oncogene; 2002 Sep; 21(42):6471-9. PubMed ID: 12226750
    [TBL] [Abstract][Full Text] [Related]  

  • 39. DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer.
    Chan DW; Ye R; Veillette CJ; Lees-Miller SP
    Biochemistry; 1999 Feb; 38(6):1819-28. PubMed ID: 10026262
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.
    Douglas P; Sapkota GP; Morrice N; Yu Y; Goodarzi AA; Merkle D; Meek K; Alessi DR; Lees-Miller SP
    Biochem J; 2002 Nov; 368(Pt 1):243-51. PubMed ID: 12186630
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.