These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 15680679)

  • 1. Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).
    Majer BJ; Hofer E; Cavin C; Lhoste E; Uhl M; Glatt HR; Meinl W; Knasmüller S
    Food Chem Toxicol; 2005 Mar; 43(3):433-41. PubMed ID: 15680679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
    Huber WW; Teitel CH; Coles BF; King RS; Wiese FW; Kaderlik KR; Casciano DA; Shaddock JG; Mulder GJ; Ilett KF; Kadlubar FF
    Environ Mol Mutagen; 2004; 44(4):265-76. PubMed ID: 15468054
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells.
    Uhl M; Ecker S; Kassie F; Lhoste E; Chakraborty A; Mohn G; Knasmüller S
    Arch Toxicol; 2003 Aug; 77(8):477-84. PubMed ID: 12856103
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genotoxic effects of dietary and lifestyle related carcinogens in human derived hepatoma (HepG2, Hep3B) cells.
    Majer BJ; Mersch-Sundermann V; Darroudi F; Laky B; de Wit K; Knasmüller S
    Mutat Res; 2004 Jul; 551(1-2):153-66. PubMed ID: 15225590
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhancement of the chemoprotective enzymes glucuronosyl transferase and glutathione transferase in specific organs of the rat by the coffee components kahweol and cafestol.
    Huber WW; Prustomersky S; Delbanco E; Uhl M; Scharf G; Turesky RJ; Thier R; Schulte-Hermann R
    Arch Toxicol; 2002 May; 76(4):209-17. PubMed ID: 12029384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
    Huber WW; Rossmanith W; Grusch M; Haslinger E; Prustomersky S; Peter-Vörösmarty B; Parzefall W; Scharf G; Schulte-Hermann R
    Food Chem Toxicol; 2008 Apr; 46(4):1230-8. PubMed ID: 17983700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
    Shimada T; Guengerich FP
    Cancer Res; 1991 Oct; 51(19):5284-91. PubMed ID: 1913651
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
    Higgins LG; Cavin C; Itoh K; Yamamoto M; Hayes JD
    Toxicol Appl Pharmacol; 2008 Feb; 226(3):328-37. PubMed ID: 18028974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk.
    Huber WW; Parzefall W
    Methods Enzymol; 2005; 401():307-41. PubMed ID: 16399395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
    Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
    Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.
    Winter HK; Ehrlich VA; Grusch M; Lackner A; Schulte-Hermann R; Grasl-Kraupp B; Mikulits W; Knasmüller S
    Mutat Res; 2008 Dec; 657(2):133-9. PubMed ID: 18790080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats.
    Turesky RJ; Richoz J; Constable A; Curtis KD; Dingley KH; Turteltaub KW
    Chem Biol Interact; 2003 Jun; 145(3):251-65. PubMed ID: 12732453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells.
    Malfatti MA; Wu RW; Felton JS
    Mutat Res; 2005 Mar; 570(2):205-14. PubMed ID: 15708579
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
    Le Hegarat L; Dumont J; Josse R; Huet S; Lanceleur R; Mourot A; Poul JM; Guguen-Guillouzo C; Guillouzo A; Fessard V
    Mutagenesis; 2010 Nov; 25(6):555-60. PubMed ID: 20675360
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties.
    Wilkening S; Stahl F; Bader A
    Drug Metab Dispos; 2003 Aug; 31(8):1035-42. PubMed ID: 12867492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
    Cavin C; Holzhaeuser D; Scharf G; Constable A; Huber WW; Schilter B
    Food Chem Toxicol; 2002 Aug; 40(8):1155-63. PubMed ID: 12067578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
    Arranz N; Haza AI; García A; Möller L; Rafter J; Morales P
    Food Chem Toxicol; 2007 Sep; 45(9):1662-9. PubMed ID: 17434656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Frandsen H; Alexander J
    Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers.
    Bichler J; Cavin C; Simic T; Chakraborty A; Ferk F; Hoelzl C; Schulte-Hermann R; Kundi M; Haidinger G; Angelis K; Knasmüller S
    Food Chem Toxicol; 2007 Aug; 45(8):1428-36. PubMed ID: 17376579
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates S-phase checkpoint and apoptosis, and induces gene mutation in human lymphoblastoid TK6 cells.
    Zhu H; Boobis AR; Gooderham NJ
    Cancer Res; 2000 Mar; 60(5):1283-9. PubMed ID: 10728688
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.