239 related articles for article (PubMed ID: 15680679)
1. Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).
Majer BJ; Hofer E; Cavin C; Lhoste E; Uhl M; Glatt HR; Meinl W; Knasmüller S
Food Chem Toxicol; 2005 Mar; 43(3):433-41. PubMed ID: 15680679
[TBL] [Abstract][Full Text] [Related]
2. Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
Huber WW; Teitel CH; Coles BF; King RS; Wiese FW; Kaderlik KR; Casciano DA; Shaddock JG; Mulder GJ; Ilett KF; Kadlubar FF
Environ Mol Mutagen; 2004; 44(4):265-76. PubMed ID: 15468054
[TBL] [Abstract][Full Text] [Related]
3. Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells.
Uhl M; Ecker S; Kassie F; Lhoste E; Chakraborty A; Mohn G; Knasmüller S
Arch Toxicol; 2003 Aug; 77(8):477-84. PubMed ID: 12856103
[TBL] [Abstract][Full Text] [Related]
4. Genotoxic effects of dietary and lifestyle related carcinogens in human derived hepatoma (HepG2, Hep3B) cells.
Majer BJ; Mersch-Sundermann V; Darroudi F; Laky B; de Wit K; Knasmüller S
Mutat Res; 2004 Jul; 551(1-2):153-66. PubMed ID: 15225590
[TBL] [Abstract][Full Text] [Related]
5. Enhancement of the chemoprotective enzymes glucuronosyl transferase and glutathione transferase in specific organs of the rat by the coffee components kahweol and cafestol.
Huber WW; Prustomersky S; Delbanco E; Uhl M; Scharf G; Turesky RJ; Thier R; Schulte-Hermann R
Arch Toxicol; 2002 May; 76(4):209-17. PubMed ID: 12029384
[TBL] [Abstract][Full Text] [Related]
6. Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Huber WW; Rossmanith W; Grusch M; Haslinger E; Prustomersky S; Peter-Vörösmarty B; Parzefall W; Scharf G; Schulte-Hermann R
Food Chem Toxicol; 2008 Apr; 46(4):1230-8. PubMed ID: 17983700
[TBL] [Abstract][Full Text] [Related]
7. Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
Shimada T; Guengerich FP
Cancer Res; 1991 Oct; 51(19):5284-91. PubMed ID: 1913651
[TBL] [Abstract][Full Text] [Related]
8. Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
Higgins LG; Cavin C; Itoh K; Yamamoto M; Hayes JD
Toxicol Appl Pharmacol; 2008 Feb; 226(3):328-37. PubMed ID: 18028974
[TBL] [Abstract][Full Text] [Related]
9. Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk.
Huber WW; Parzefall W
Methods Enzymol; 2005; 401():307-41. PubMed ID: 16399395
[TBL] [Abstract][Full Text] [Related]
10. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
[TBL] [Abstract][Full Text] [Related]
11. Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.
Winter HK; Ehrlich VA; Grusch M; Lackner A; Schulte-Hermann R; Grasl-Kraupp B; Mikulits W; Knasmüller S
Mutat Res; 2008 Dec; 657(2):133-9. PubMed ID: 18790080
[TBL] [Abstract][Full Text] [Related]
12. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats.
Turesky RJ; Richoz J; Constable A; Curtis KD; Dingley KH; Turteltaub KW
Chem Biol Interact; 2003 Jun; 145(3):251-65. PubMed ID: 12732453
[TBL] [Abstract][Full Text] [Related]
13. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells.
Malfatti MA; Wu RW; Felton JS
Mutat Res; 2005 Mar; 570(2):205-14. PubMed ID: 15708579
[TBL] [Abstract][Full Text] [Related]
14. Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
Le Hegarat L; Dumont J; Josse R; Huet S; Lanceleur R; Mourot A; Poul JM; Guguen-Guillouzo C; Guillouzo A; Fessard V
Mutagenesis; 2010 Nov; 25(6):555-60. PubMed ID: 20675360
[TBL] [Abstract][Full Text] [Related]
15. Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties.
Wilkening S; Stahl F; Bader A
Drug Metab Dispos; 2003 Aug; 31(8):1035-42. PubMed ID: 12867492
[TBL] [Abstract][Full Text] [Related]
16. Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Cavin C; Holzhaeuser D; Scharf G; Constable A; Huber WW; Schilter B
Food Chem Toxicol; 2002 Aug; 40(8):1155-63. PubMed ID: 12067578
[TBL] [Abstract][Full Text] [Related]
17. Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Arranz N; Haza AI; García A; Möller L; Rafter J; Morales P
Food Chem Toxicol; 2007 Sep; 45(9):1662-9. PubMed ID: 17434656
[TBL] [Abstract][Full Text] [Related]
18. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Frandsen H; Alexander J
Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
[TBL] [Abstract][Full Text] [Related]
19. Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers.
Bichler J; Cavin C; Simic T; Chakraborty A; Ferk F; Hoelzl C; Schulte-Hermann R; Kundi M; Haidinger G; Angelis K; Knasmüller S
Food Chem Toxicol; 2007 Aug; 45(8):1428-36. PubMed ID: 17376579
[TBL] [Abstract][Full Text] [Related]
20. The food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates S-phase checkpoint and apoptosis, and induces gene mutation in human lymphoblastoid TK6 cells.
Zhu H; Boobis AR; Gooderham NJ
Cancer Res; 2000 Mar; 60(5):1283-9. PubMed ID: 10728688
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]