BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 15684389)

  • 1. Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.
    Salerno M; Palmieri D; Bouadis A; Halverson D; Steeg PS
    Mol Cell Biol; 2005 Feb; 25(4):1379-88. PubMed ID: 15684389
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer.
    Palmieri D; Halverson DO; Ouatas T; Horak CE; Salerno M; Johnson J; Figg WD; Hollingshead M; Hursting S; Berrigan D; Steinberg SM; Merino MJ; Steeg PS
    J Natl Cancer Inst; 2005 May; 97(9):632-42. PubMed ID: 15870434
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds.
    Ouatas T; Halverson D; Steeg PS
    Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3763-72. PubMed ID: 14506169
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.
    Hartsough MT; Clare SE; Mair M; Elkahloun AG; Sgroi D; Osborne CK; Clark G; Steeg PS
    Cancer Res; 2001 Mar; 61(5):2320-7. PubMed ID: 11280805
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
    Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
    Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition.
    Guo W; Reigan P; Siegel D; Zirrolli J; Gustafson D; Ross D
    Cancer Res; 2005 Nov; 65(21):10006-15. PubMed ID: 16267026
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line.
    Price JT; Quinn JM; Sims NA; Vieusseux J; Waldeck K; Docherty SE; Myers D; Nakamura A; Waltham MC; Gillespie MT; Thompson EW
    Cancer Res; 2005 Jun; 65(11):4929-38. PubMed ID: 15930315
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin.
    Bonvini P; Gastaldi T; Falini B; Rosolen A
    Cancer Res; 2002 Mar; 62(5):1559-66. PubMed ID: 11888936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P53 is a regulator of the metastasis suppressor gene Nm23-H1.
    Chen SL; Wu YS; Shieh HY; Yen CC; Shen JJ; Lin KH
    Mol Carcinog; 2003 Apr; 36(4):204-14. PubMed ID: 12669312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells.
    Roforth MM; Tan C
    Anticancer Drugs; 2008 Aug; 19(7):681-8. PubMed ID: 18594209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
    Horak CE; Lee JH; Elkahloun AG; Boissan M; Dumont S; Maga TK; Arnaud-Dabernat S; Palmieri D; Stetler-Stevenson WG; Lacombe ML; Meltzer PS; Steeg PS
    Cancer Res; 2007 Aug; 67(15):7238-46. PubMed ID: 17671192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nm23-H1: a metastasis-associated gene.
    Tee YT; Chen GD; Lin LY; Ko JL; Wang PH
    Taiwan J Obstet Gynecol; 2006 Jun; 45(2):107-13. PubMed ID: 17197349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.
    Hartsough MT; Morrison DK; Salerno M; Palmieri D; Ouatas T; Mair M; Patrick J; Steeg PS
    J Biol Chem; 2002 Aug; 277(35):32389-99. PubMed ID: 12105213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
    Che G; Chen J; Liu L; Wang Y; Li L; Qin Y; Zhou Q
    Neoplasma; 2006; 53(6):530-7. PubMed ID: 17167724
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
    Bisht KS; Bradbury CM; Mattson D; Kaushal A; Sowers A; Markovina S; Ortiz KL; Sieck LK; Isaacs JS; Brechbiel MW; Mitchell JB; Neckers LM; Gius D
    Cancer Res; 2003 Dec; 63(24):8984-95. PubMed ID: 14695217
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of kinase suppressor of Ras-1 expression and anticancer drug sensitivity in human cancer cell lines.
    Stoeger SM; Cowan KH
    Cancer Chemother Pharmacol; 2009 Apr; 63(5):807-18. PubMed ID: 18661133
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coadministration of the heat shock protein 90 antagonist 17-allylamino- 17-demethoxygeldanamycin with suberoylanilide hydroxamic acid or sodium butyrate synergistically induces apoptosis in human leukemia cells.
    Rahmani M; Yu C; Dai Y; Reese E; Ahmed W; Dent P; Grant S
    Cancer Res; 2003 Dec; 63(23):8420-7. PubMed ID: 14679005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
    Boissan M; De Wever O; Lizarraga F; Wendum D; Poincloux R; Chignard N; Desbois-Mouthon C; Dufour S; Nawrocki-Raby B; Birembaut P; Bracke M; Chavrier P; Gespach C; Lacombe ML
    Cancer Res; 2010 Oct; 70(19):7710-22. PubMed ID: 20841469
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.
    Leone A; Flatow U; VanHoutte K; Steeg PS
    Oncogene; 1993 Sep; 8(9):2325-33. PubMed ID: 8395676
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol.
    Solit DB; Basso AD; Olshen AB; Scher HI; Rosen N
    Cancer Res; 2003 May; 63(9):2139-44. PubMed ID: 12727831
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.