BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

489 related articles for article (PubMed ID: 15684421)

  • 1. Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure.
    McEwen E; Kedersha N; Song B; Scheuner D; Gilks N; Han A; Chen JJ; Anderson P; Kaufman RJ
    J Biol Chem; 2005 Apr; 280(17):16925-33. PubMed ID: 15684421
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses.
    Lu L; Han AP; Chen JJ
    Mol Cell Biol; 2001 Dec; 21(23):7971-80. PubMed ID: 11689689
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency.
    Han AP; Yu C; Lu L; Fujiwara Y; Browne C; Chin G; Fleming M; Leboulch P; Orkin SH; Chen JJ
    EMBO J; 2001 Dec; 20(23):6909-18. PubMed ID: 11726526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.
    Wehner KA; Schütz S; Sarnow P
    Mol Cell Biol; 2010 Apr; 30(8):2006-16. PubMed ID: 20154146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast.
    Dever TE; Chen JJ; Barber GN; Cigan AM; Feng L; Donahue TF; London IM; Katze MG; Hinnebusch AG
    Proc Natl Acad Sci U S A; 1993 May; 90(10):4616-20. PubMed ID: 8099443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.
    Dang Y; Kedersha N; Low WK; Romo D; Gorospe M; Kaufman R; Anderson P; Liu JO
    J Biol Chem; 2006 Oct; 281(43):32870-8. PubMed ID: 16951406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dihydrocapsaicin induces translational repression and stress granule through HRI-eIF2α phosphorylation axis.
    De K; Jayabalan AK; Mariappan R; Ramasamy VS; Ohn T
    Biochem Biophys Res Commun; 2022 Jan; 588():125-132. PubMed ID: 34953209
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.
    Deng J; Lu PD; Zhang Y; Scheuner D; Kaufman RJ; Sonenberg N; Harding HP; Ron D
    Mol Cell Biol; 2004 Dec; 24(23):10161-8. PubMed ID: 15542827
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2α Kinase HRI Induces Synaptogenesis.
    Ill-Raga G; Tajes M; Busquets-García A; Ramos-Fernández E; Vargas LM; Bosch-Morató M; Guivernau B; Valls-Comamala V; Eraso-Pichot A; Guix FX; Fandos C; Rosen MD; Rabinowitz MH; Maldonado R; Alvarez AR; Ozaita A; Muñoz FJ
    Antioxid Redox Signal; 2015 May; 22(15):1295-307. PubMed ID: 25706765
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autophosphorylation of threonine 485 in the activation loop is essential for attaining eIF2alpha kinase activity of HRI.
    Rafie-Kolpin M; Han AP; Chen JJ
    Biochemistry; 2003 Jun; 42(21):6536-44. PubMed ID: 12767237
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress tone.
    Acharya P; Chen JJ; Correia MA
    Mol Pharmacol; 2010 Apr; 77(4):575-92. PubMed ID: 20071449
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of eukaryotic initiation factor 2 by heme-regulated inhibitor kinase-related protein kinases in Schizosaccharomyces pombe is important for fesistance to environmental stresses.
    Zhan K; Vattem KM; Bauer BN; Dever TE; Chen JJ; Wek RC
    Mol Cell Biol; 2002 Oct; 22(20):7134-46. PubMed ID: 12242291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of translational initiation by activators of the glucose-regulated stress protein and heat shock protein stress response systems. Role of the interferon-inducible double-stranded RNA-activated eukaryotic initiation factor 2alpha kinase.
    Brostrom CO; Prostko CR; Kaufman RJ; Brostrom MA
    J Biol Chem; 1996 Oct; 271(40):24995-5002. PubMed ID: 8798781
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity.
    Ricketts MD; Emptage RP; Blobel GA; Marmorstein R
    J Biol Chem; 2022 Oct; 298(10):102451. PubMed ID: 36063997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis.
    Zhang S; Macias-Garcia A; Ulirsch JC; Velazquez J; Butty VL; Levine SS; Sankaran VG; Chen JJ
    Elife; 2019 Apr; 8():. PubMed ID: 31033440
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis.
    Wu S; Tan M; Hu Y; Wang JL; Scheuner D; Kaufman RJ
    J Biol Chem; 2004 Aug; 279(33):34898-902. PubMed ID: 15184376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stress-induced translation of ATF5 mRNA is regulated by the 5'-untranslated region.
    Watatani Y; Ichikawa K; Nakanishi N; Fujimoto M; Takeda H; Kimura N; Hirose H; Takahashi S; Takahashi Y
    J Biol Chem; 2008 Feb; 283(5):2543-53. PubMed ID: 18055463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stress granule formation mediates the inhibition of colonic Hsp70 translation by interferon-gamma and tumor necrosis factor-alpha.
    Hu S; Claud EC; Musch MW; Chang EB
    Am J Physiol Gastrointest Liver Physiol; 2010 Apr; 298(4):G481-92. PubMed ID: 20110459
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucosamine-induced phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 is mediated by the protein kinase R-like endoplasmic-reticulum associated kinase.
    Kline CL; Schrufer TL; Jefferson LS; Kimball SR
    Int J Biochem Cell Biol; 2006; 38(5-6):1004-14. PubMed ID: 16324875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Large G3BP-induced granules trigger eIF2α phosphorylation.
    Reineke LC; Dougherty JD; Pierre P; Lloyd RE
    Mol Biol Cell; 2012 Sep; 23(18):3499-510. PubMed ID: 22833567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.