These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 15687493)

  • 1. Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17.
    Pandey AV; Miller WL
    J Biol Chem; 2005 Apr; 280(14):13265-71. PubMed ID: 15687493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
    Geller DH; Auchus RJ; Miller WL
    Mol Endocrinol; 1999 Jan; 13(1):167-75. PubMed ID: 9892022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17.
    Soucy P; Luu-The V
    J Steroid Biochem Mol Biol; 2002 Jan; 80(1):71-5. PubMed ID: 11867265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17.
    Holien JK; Parker MW; Conley AJ; Corbin CJ; Rodgers RJ; Martin LL
    Curr Protein Pept Sci; 2017; 18(5):515-521. PubMed ID: 28000554
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
    Soucy P; Luu-The V
    Eur J Biochem; 2000 Jun; 267(11):3243-7. PubMed ID: 10824109
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
    Auchus RJ; Lee TC; Miller WL
    J Biol Chem; 1998 Feb; 273(6):3158-65. PubMed ID: 9452426
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase.
    Soucy P; Lacoste L; Luu-The V
    Eur J Biochem; 2003 Mar; 270(6):1349-55. PubMed ID: 12631293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The primate adrenal zona reticularis is defined by expression of cytochrome b5, 17alpha-hydroxylase/17,20-lyase cytochrome P450 (P450c17) and NADPH-cytochrome P450 reductase (reductase) but not 3beta-hydroxysteroid dehydrogenase/delta5-4 isomerase (3beta-HSD).
    Mapes S; Corbin CJ; Tarantal A; Conley A
    J Clin Endocrinol Metab; 1999 Sep; 84(9):3382-5. PubMed ID: 10487714
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of human cytochrome P450c17 by p38α selectively increases 17,20 lyase activity and androgen biosynthesis.
    Tee MK; Miller WL
    J Biol Chem; 2013 Aug; 288(33):23903-13. PubMed ID: 23836902
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
    Lin D; Black SM; Nagahama Y; Miller WL
    Endocrinology; 1993 Jun; 132(6):2498-506. PubMed ID: 8504753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The developmental increase in adrenocortical 17,20-lyase activity (biochemical adrenarche) is driven primarily by increasing cytochrome b5 in neonatal rhesus macaques.
    Nguyen AD; Corbin CJ; Pattison JC; Bird IM; Conley AJ
    Endocrinology; 2009 Apr; 150(4):1748-56. PubMed ID: 19036885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
    Gonzalez E; Guengerich FP
    J Biol Chem; 2017 Aug; 292(32):13168-13185. PubMed ID: 28684414
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of cytochrome b5 gene transcription by Sp3, GATA-6, and steroidogenic factor 1 in human adrenal NCI-H295A cells.
    Huang N; Dardis A; Miller WL
    Mol Endocrinol; 2005 Aug; 19(8):2020-34. PubMed ID: 15831526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of porcine cytochrome b5A and cytochrome b5B in the regulation of cytochrome P45017A1 activities.
    Billen MJ; Squires EJ
    J Steroid Biochem Mol Biol; 2009 Jan; 113(1-2):98-104. PubMed ID: 19101629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The regulation of 17,20 lyase activity.
    Miller WL; Auchus RJ; Geller DH
    Steroids; 1997 Jan; 62(1):133-42. PubMed ID: 9029728
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
    Brock BJ; Waterman MR
    Biochemistry; 1999 Feb; 38(5):1598-606. PubMed ID: 9931027
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase.
    Jenkins CM; Waterman MR
    Biochemistry; 1998 Apr; 37(17):6106-13. PubMed ID: 9558349
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human cytochrome b5 requires residues E48 and E49 to stimulate the 17,20-lyase activity of cytochrome P450c17.
    Naffin-Olivos JL; Auchus RJ
    Biochemistry; 2006 Jan; 45(3):755-62. PubMed ID: 16411751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.
    Peng HM; Im SC; Pearl NM; Turcu AF; Rege J; Waskell L; Auchus RJ
    Biochemistry; 2016 Aug; 55(31):4356-65. PubMed ID: 27426448
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytochrome P450c17 from porcine and bovine adrenal catalyses the formation of 5,16-androstadien-3 beta-ol from pregnenolone in the presence of cytochrome b5.
    Meadus WJ; Mason JI; Squires EJ
    J Steroid Biochem Mol Biol; 1993 Nov; 46(5):565-72. PubMed ID: 8240978
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.