BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 15688078)

  • 1. What's wrong with our cancer models?
    Kamb A
    Nat Rev Drug Discov; 2005 Feb; 4(2):161-5. PubMed ID: 15688078
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Murine models to evaluate novel and conventional therapeutic strategies for cancer.
    Talmadge JE; Singh RK; Fidler IJ; Raz A
    Am J Pathol; 2007 Mar; 170(3):793-804. PubMed ID: 17322365
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.
    Sachs N; de Ligt J; Kopper O; Gogola E; Bounova G; Weeber F; Balgobind AV; Wind K; Gracanin A; Begthel H; Korving J; van Boxtel R; Duarte AA; Lelieveld D; van Hoeck A; Ernst RF; Blokzijl F; Nijman IJ; Hoogstraat M; van de Ven M; Egan DA; Zinzalla V; Moll J; Boj SF; Voest EE; Wessels L; van Diest PJ; Rottenberg S; Vries RGJ; Cuppen E; Clevers H
    Cell; 2018 Jan; 172(1-2):373-386.e10. PubMed ID: 29224780
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Organoid cultures derived from patients with advanced prostate cancer.
    Gao D; Vela I; Sboner A; Iaquinta PJ; Karthaus WR; Gopalan A; Dowling C; Wanjala JN; Undvall EA; Arora VK; Wongvipat J; Kossai M; Ramazanoglu S; Barboza LP; Di W; Cao Z; Zhang QF; Sirota I; Ran L; MacDonald TY; Beltran H; Mosquera JM; Touijer KA; Scardino PT; Laudone VP; Curtis KR; Rathkopf DE; Morris MJ; Danila DC; Slovin SF; Solomon SB; Eastham JA; Chi P; Carver B; Rubin MA; Scher HI; Clevers H; Sawyers CL; Chen Y
    Cell; 2014 Sep; 159(1):176-187. PubMed ID: 25201530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Advances in the preclinical testing of cancer therapeutic hypotheses.
    Caponigro G; Sellers WR
    Nat Rev Drug Discov; 2011 Mar; 10(3):179-87. PubMed ID: 21358737
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.
    Sato T; Vries RG; Snippert HJ; van de Wetering M; Barker N; Stange DE; van Es JH; Abo A; Kujala P; Peters PJ; Clevers H
    Nature; 2009 May; 459(7244):262-5. PubMed ID: 19329995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
    Broutier L; Mastrogiovanni G; Verstegen MM; Francies HE; Gavarró LM; Bradshaw CR; Allen GE; Arnes-Benito R; Sidorova O; Gaspersz MP; Georgakopoulos N; Koo BK; Dietmann S; Davies SE; Praseedom RK; Lieshout R; IJzermans JNM; Wigmore SJ; Saeb-Parsy K; Garnett MJ; van der Laan LJ; Huch M
    Nat Med; 2017 Dec; 23(12):1424-1435. PubMed ID: 29131160
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Organoids in cancer research.
    Drost J; Clevers H
    Nat Rev Cancer; 2018 Jul; 18(7):407-418. PubMed ID: 29692415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Patient-derived xenograft models: an emerging platform for translational cancer research.
    Hidalgo M; Amant F; Biankin AV; Budinská E; Byrne AT; Caldas C; Clarke RB; de Jong S; Jonkers J; Mælandsmo GM; Roman-Roman S; Seoane J; Trusolino L; Villanueva A
    Cancer Discov; 2014 Sep; 4(9):998-1013. PubMed ID: 25185190
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interrogating open issues in cancer precision medicine with patient-derived xenografts.
    Byrne AT; Alférez DG; Amant F; Annibali D; Arribas J; Biankin AV; Bruna A; Budinská E; Caldas C; Chang DK; Clarke RB; Clevers H; Coukos G; Dangles-Marie V; Eckhardt SG; Gonzalez-Suarez E; Hermans E; Hidalgo M; Jarzabek MA; de Jong S; Jonkers J; Kemper K; Lanfrancone L; Mælandsmo GM; Marangoni E; Marine JC; Medico E; Norum JH; Palmer HG; Peeper DS; Pelicci PG; Piris-Gimenez A; Roman-Roman S; Rueda OM; Seoane J; Serra V; Soucek L; Vanhecke D; Villanueva A; Vinolo E; Bertotti A; Trusolino L
    Nat Rev Cancer; 2017 Apr; 17(4):254-268. PubMed ID: 28104906
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
    Vlachogiannis G; Hedayat S; Vatsiou A; Jamin Y; Fernández-Mateos J; Khan K; Lampis A; Eason K; Huntingford I; Burke R; Rata M; Koh DM; Tunariu N; Collins D; Hulkki-Wilson S; Ragulan C; Spiteri I; Moorcraft SY; Chau I; Rao S; Watkins D; Fotiadis N; Bali M; Darvish-Damavandi M; Lote H; Eltahir Z; Smyth EC; Begum R; Clarke PA; Hahne JC; Dowsett M; de Bono J; Workman P; Sadanandam A; Fassan M; Sansom OJ; Eccles S; Starling N; Braconi C; Sottoriva A; Robinson SP; Cunningham D; Valeri N
    Science; 2018 Feb; 359(6378):920-926. PubMed ID: 29472484
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prospective derivation of a living organoid biobank of colorectal cancer patients.
    van de Wetering M; Francies HE; Francis JM; Bounova G; Iorio F; Pronk A; van Houdt W; van Gorp J; Taylor-Weiner A; Kester L; McLaren-Douglas A; Blokker J; Jaksani S; Bartfeld S; Volckman R; van Sluis P; Li VS; Seepo S; Sekhar Pedamallu C; Cibulskis K; Carter SL; McKenna A; Lawrence MS; Lichtenstein L; Stewart C; Koster J; Versteeg R; van Oudenaarden A; Saez-Rodriguez J; Vries RG; Getz G; Wessels L; Stratton MR; McDermott U; Meyerson M; Garnett MJ; Clevers H
    Cell; 2015 May; 161(4):933-45. PubMed ID: 25957691
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Organoid models of human and mouse ductal pancreatic cancer.
    Boj SF; Hwang CI; Baker LA; Chio II; Engle DD; Corbo V; Jager M; Ponz-Sarvise M; Tiriac H; Spector MS; Gracanin A; Oni T; Yu KH; van Boxtel R; Huch M; Rivera KD; Wilson JP; Feigin ME; Öhlund D; Handly-Santana A; Ardito-Abraham CM; Ludwig M; Elyada E; Alagesan B; Biffi G; Yordanov GN; Delcuze B; Creighton B; Wright K; Park Y; Morsink FH; Molenaar IQ; Borel Rinkes IH; Cuppen E; Hao Y; Jin Y; Nijman IJ; Iacobuzio-Donahue C; Leach SD; Pappin DJ; Hammell M; Klimstra DS; Basturk O; Hruban RH; Offerhaus GJ; Vries RG; Clevers H; Tuveson DA
    Cell; 2015 Jan; 160(1-2):324-38. PubMed ID: 25557080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling Development and Disease with Organoids.
    Clevers H
    Cell; 2016 Jun; 165(7):1586-1597. PubMed ID: 27315476
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.
    Matano M; Date S; Shimokawa M; Takano A; Fujii M; Ohta Y; Watanabe T; Kanai T; Sato T
    Nat Med; 2015 Mar; 21(3):256-62. PubMed ID: 25706875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation and in vitro expansion of human colonic stem cells.
    Jung P; Sato T; Merlos-Suárez A; Barriga FM; Iglesias M; Rossell D; Auer H; Gallardo M; Blasco MA; Sancho E; Clevers H; Batlle E
    Nat Med; 2011 Sep; 17(10):1225-7. PubMed ID: 21892181
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
    Sato T; Stange DE; Ferrante M; Vries RG; Van Es JH; Van den Brink S; Van Houdt WJ; Pronk A; Van Gorp J; Siersema PD; Clevers H
    Gastroenterology; 2011 Nov; 141(5):1762-72. PubMed ID: 21889923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spheroids and organoids derived from colorectal cancer as tools for
    Ahmad Zawawi SS; Salleh EA; Musa M
    Explor Target Antitumor Ther; 2024; 5(2):409-431. PubMed ID: 38745769
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modelling esophageal adenocarcinoma and Barrett's esophagus with patient-derived organoids.
    Milne JV; Mustafa EH; Clemons NJ
    Front Mol Biosci; 2024; 11():1382070. PubMed ID: 38721276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Organoids derived from metastatic cancers: Present and future.
    Zheng X; Zhang X; Yu S
    Heliyon; 2024 May; 10(9):e30457. PubMed ID: 38720734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.