273 related articles for article (PubMed ID: 15688426)
1. Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics.
Xiao Z; Xue J; Semizarov D; Sowin TJ; Rosenberg SH; Zhang H
Int J Cancer; 2005 Jul; 115(4):528-38. PubMed ID: 15688426
[TBL] [Abstract][Full Text] [Related]
2. A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation.
Xiao Z; Xue J; Sowin TJ; Rosenberg SH; Zhang H
Oncogene; 2005 Feb; 24(8):1403-11. PubMed ID: 15608676
[TBL] [Abstract][Full Text] [Related]
3. Cyclin B1 is an efficacy-predicting biomarker for Chk1 inhibitors.
Xiao Z; Xue J; Gu WZ; Bui M; Li G; Tao ZF; Lin NH; Sowin TJ; Zhang H
Biomarkers; 2008 Sep; 13(6):579-96. PubMed ID: 18671143
[TBL] [Abstract][Full Text] [Related]
4. Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.
Xiao Z; Xue J; Sowin TJ; Zhang H
Mol Cancer Ther; 2006 Aug; 5(8):1935-43. PubMed ID: 16928813
[TBL] [Abstract][Full Text] [Related]
5. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
Pan Y; Ren KH; He HW; Shao RG
Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
[TBL] [Abstract][Full Text] [Related]
6. Tubulozole-induced G2/M cell cycle arrest in human colon cancer cells through formation of microtubule polymerization mediated by ERK1/2 and Chk1 kinase activation.
Chou YH; Ho YS; Wu CC; Chai CY; Chen SC; Lee CH; Tsai PS; Wu CH
Food Chem Toxicol; 2007 Aug; 45(8):1356-67. PubMed ID: 17329004
[TBL] [Abstract][Full Text] [Related]
7. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
Hirose Y; Berger MS; Pieper RO
Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
[TBL] [Abstract][Full Text] [Related]
8. Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis.
Chen JS; Lin SY; Tso WL; Yeh GC; Lee WS; Tseng H; Chen LC; Ho YS
Mol Carcinog; 2006 Jul; 45(7):461-78. PubMed ID: 16649252
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of checkpoint kinase 1 abrogates G2/M checkpoint activation and promotes apoptosis under heat stress.
Furusawa Y; Iizumi T; Fujiwara Y; Zhao QL; Tabuchi Y; Nomura T; Kondo T
Apoptosis; 2012 Jan; 17(1):102-12. PubMed ID: 22080164
[TBL] [Abstract][Full Text] [Related]
10. Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells.
Gao Q; Huang X; Tang D; Cao Y; Chen G; Lu Y; Zhuang L; Wang S; Xu G; Zhou J; Ma D
Apoptosis; 2006 Oct; 11(10):1789-800. PubMed ID: 16927022
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Eg5 acts synergistically with checkpoint abrogation in promoting mitotic catastrophe.
Chen Y; Chow JP; Poon RY
Mol Cancer Res; 2012 May; 10(5):626-35. PubMed ID: 22522457
[TBL] [Abstract][Full Text] [Related]
12. Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells.
Bo S; Hui H; Li W; Hui L; Hong X; Lin D; Dai WX; Wu YH; Ai XH; Hao J; Qi S
Food Chem Toxicol; 2014 Jun; 68():61-70. PubMed ID: 24650757
[TBL] [Abstract][Full Text] [Related]
13. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
Chung KS; Choi HE; Shin JS; Cho YW; Choi JH; Cho WJ; Lee KT
Carcinogenesis; 2013 Aug; 34(8):1852-60. PubMed ID: 23615402
[TBL] [Abstract][Full Text] [Related]
14. Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells.
Fujie Y; Yamamoto H; Ngan CY; Takagi A; Hayashi T; Suzuki R; Ezumi K; Takemasa I; Ikeda M; Sekimoto M; Matsuura N; Monden M
Jpn J Clin Oncol; 2005 Aug; 35(8):453-63. PubMed ID: 16024531
[TBL] [Abstract][Full Text] [Related]
15. The Chk1-Cdc25C regulation is involved in sensitizing A253 cells to a novel topoisomerase I inhibitor BNP1350 by bax gene transfer.
Yin M; Hapke G; Guo B; Azrak RG; Frank C; Rustum YM
Oncogene; 2001 Aug; 20(38):5249-57. PubMed ID: 11536038
[TBL] [Abstract][Full Text] [Related]
16. Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage.
Nabha SM; Mohammad RM; Dandashi MH; Coupaye-Gerard B; Aboukameel A; Pettit GR; Al-Katib AM
Clin Cancer Res; 2002 Aug; 8(8):2735-41. PubMed ID: 12171907
[TBL] [Abstract][Full Text] [Related]
17. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
[TBL] [Abstract][Full Text] [Related]
18. Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.
Jin ZH; Kurosu T; Yamaguchi M; Arai A; Miura O
Oncogene; 2005 Mar; 24(12):1973-81. PubMed ID: 15674326
[TBL] [Abstract][Full Text] [Related]
19. Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.
Chen Z; Xiao Z; Gu WZ; Xue J; Bui MH; Kovar P; Li G; Wang G; Tao ZF; Tong Y; Lin NH; Sham HL; Wang JY; Sowin TJ; Rosenberg SH; Zhang H
Int J Cancer; 2006 Dec; 119(12):2784-94. PubMed ID: 17019715
[TBL] [Abstract][Full Text] [Related]
20. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
Menendez JA; Vellon L; Colomer R; Lupu R
Int J Cancer; 2005 May; 115(1):19-35. PubMed ID: 15657900
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
