BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 15689153)

  • 1. Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, synthesis, and biological evaluation of phenol bioisosteric analogues of benzazepine D1/D5 antagonists.
    Wu WL; Burnett DA; Spring R; Greenlee WJ; Smith M; Favreau L; Fawzi A; Zhang H; Lachowicz JE
    J Med Chem; 2005 Feb; 48(3):680-93. PubMed ID: 15689153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. (+/-)-3-[4'-(N,N-dimethylamino)cinnamyl]benzazepine analogs: novel dopamine D1 receptor antagonists.
    Shah JH; Kline RH; Geter-Douglass B; Izenwasser S; Witkin JM; Newman AH
    J Med Chem; 1996 Aug; 39(17):3423-8. PubMed ID: 8765528
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of spinal d1/d5 receptors induces late-phase LTP of C-fiber-evoked field potentials in rat spinal dorsal horn.
    Yang HW; Zhou LJ; Hu NW; Xin WJ; Liu XG
    J Neurophysiol; 2005 Aug; 94(2):961-7. PubMed ID: 15829590
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
    Campiani G; Butini S; Fattorusso C; Catalanotti B; Gemma S; Nacci V; Morelli E; Cagnotto A; Mereghetti I; Mennini T; Carli M; Minetti P; Di Cesare MA; Mastroianni D; Scafetta N; Galletti B; Stasi MA; Castorina M; Pacifici L; Vertechy M; Di Serio S; Ghirardi O; Tinti O; Carminati P
    J Med Chem; 2004 Jan; 47(1):143-57. PubMed ID: 14695828
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Remote functionalization of SCH 39166: discovery of potent and selective benzazepine dopamine D1 receptor antagonists.
    Sasikumar TK; Burnett DA; Greenlee WJ; Smith M; Fawzi A; Zhang H; Lachowicz JE
    Bioorg Med Chem Lett; 2010 Feb; 20(3):832-5. PubMed ID: 20064718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of trans-3-(2-(4-((3-(3-(5-methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine (SB-414796): a potent and selective dopamine D3 receptor antagonist.
    Macdonald GJ; Branch CL; Hadley MS; Johnson CN; Nash DJ; Smith AB; Stemp G; Thewlis KM; Vong AK; Austin NE; Jeffrey P; Winborn KY; Boyfield I; Hagan JJ; Middlemiss DN; Reavill C; Riley GJ; Watson JM; Wood M; Parker SG; Ashby CR
    J Med Chem; 2003 Nov; 46(23):4952-64. PubMed ID: 14584946
    [TBL] [Abstract][Full Text] [Related]  

  • 7. (+/-)-(N-alkylamino)benzazepine analogs: novel dopamine D1 receptor antagonists.
    Shah JH; Izenwasser S; Geter-Douglass B; Witkin JM; Newman AH
    J Med Chem; 1995 Oct; 38(21):4284-93. PubMed ID: 7473556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differences between A 68930 and SKF 82958 could suggest synergistic roles of D1 and D5 receptors.
    NergÄrdh R; Oerther S; Fredholm BB
    Pharmacol Biochem Behav; 2005 Nov; 82(3):495-505. PubMed ID: 16318870
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sexual behavior modulates contextual fear memory through dopamine D1/D5 receptors.
    Bai HY; Cao J; Liu N; Xu L; Luo JH
    Hippocampus; 2009 Mar; 19(3):289-98. PubMed ID: 18853437
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist.
    Nakane M; Cowart MD; Hsieh GC; Miller L; Uchic ME; Chang R; Terranova MA; Donnelly-Roberts DL; Namovic MT; Miller TR; Wetter JM; Marsh K; Stewart AO; Brioni JD; Moreland RB
    Neuropharmacology; 2005 Jul; 49(1):112-21. PubMed ID: 15992586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of 3-aryl-1-[(4-phenyl-1-piperazinyl)butyl]indazole derivatives and their affinity to 5-HT1A serotonin and dopamine D1 receptors.
    Andronati S; Sava V; Makan S; Kolodeev G
    Pharmazie; 1999 Feb; 54(2):99-101. PubMed ID: 10084155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.
    Grundt P; Carlson EE; Cao J; Bennett CJ; McElveen E; Taylor M; Luedtke RR; Newman AH
    J Med Chem; 2005 Feb; 48(3):839-48. PubMed ID: 15689168
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part one: [h]-fused tricyclic systems.
    Micheli F; Bonanomi G; Braggio S; Capelli AM; Celestini P; Damiani F; Di Fabio R; Donati D; Gagliardi S; Gentile G; Hamprecht D; Petrone M; Radaelli S; Tedesco G; Terreni S; Worby A; Heidbreder C
    Bioorg Med Chem Lett; 2008 Feb; 18(3):901-7. PubMed ID: 18248991
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and discovery of 1,3-benzodiazepines as novel dopamine antagonists.
    Zhu Z; Sun ZY; Ye Y; McKittrick B; Greenlee W; Czarniecki M; Fawzi A; Zhang H; Lachowicz JE
    Bioorg Med Chem Lett; 2009 Sep; 19(17):5218-21. PubMed ID: 19643610
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dopamine/serotonin receptor ligands. 12(1): SAR studies on hexahydro-dibenz[d,g]azecines lead to 4-chloro-7-methyl-5,6,7,8,9,14-hexahydrodibenz[d,g]azecin-3-ol, the first picomolar D5-selective dopamine-receptor antagonist.
    Mohr P; Decker M; Enzensperger C; Lehmann J
    J Med Chem; 2006 Mar; 49(6):2110-6. PubMed ID: 16539400
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of new SCH 39166 analogs as potent and selective dopamine D1 receptor antagonists.
    Qiang L; Sasikumar TK; Burnett DA; Su J; Tang H; Ye Y; Mazzola RD; Zhu Z; McKittrick BA; Greenlee WJ; Fawzi A; Smith M; Zhang H; Lachowicz JE
    Bioorg Med Chem Lett; 2010 Feb; 20(3):836-40. PubMed ID: 20061148
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synergistic requirements for the induction of dopaminergic D1/D5-receptor-mediated LTP in hippocampal slices of rat CA1 in vitro.
    Navakkode S; Sajikumar S; Frey JU
    Neuropharmacology; 2007 Jun; 52(7):1547-54. PubMed ID: 17433377
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 'Click' D(1) receptor agonists with a 5-HT(1A) receptor pharmacophore producing D(2) receptor activity.
    Zhang J; Zhang H; Cai W; Yu L; Zhen X; Zhang A
    Bioorg Med Chem; 2009 Jul; 17(14):4873-80. PubMed ID: 19559623
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of human dopamine D1-like receptor agonist using a cell-based functional assay.
    Jiang N; Ou-Yang KQ; Cai SX; Hu YH; Xu ZL
    Acta Pharmacol Sin; 2005 Oct; 26(10):1181-6. PubMed ID: 16174433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ring expansions of tetrahydroprotoberberines and related dibenzo[c,g]azecines modulate the dopamine receptor subtype affinity and selectivity.
    Schulze M; Siol O; Meise W; Lehmann J; Enzensperger C
    Arch Pharm (Weinheim); 2010 Apr; 343(4):207-14. PubMed ID: 20222063
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.