These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 15691828)

  • 1. Identification of the geometric requirements for allosteric communication between the alpha- and beta-subunits of tryptophan synthase.
    Raboni S; Bettati S; Mozzarelli A
    J Biol Chem; 2005 Apr; 280(14):13450-6. PubMed ID: 15691828
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The molecular pathway for the allosteric regulation of tryptophan synthase.
    Raboni S; Pioselli B; Bettati S; Mozzarelli A
    Biochim Biophys Acta; 2003 Apr; 1647(1-2):157-60. PubMed ID: 12686126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric communication between alpha and beta subunits of tryptophan synthase: modelling the open-closed transition of the alpha subunit.
    Spyrakis F; Raboni S; Cozzini P; Bettati S; Mozzarelli A
    Biochim Biophys Acta; 2006 Jun; 1764(6):1102-9. PubMed ID: 16737856
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Allosteric communication of tryptophan synthase. Functional and regulatory properties of the beta S178P mutant.
    Marabotti A; De Biase D; Tramonti A; Bettati S; Mozzarelli A
    J Biol Chem; 2001 May; 276(21):17747-53. PubMed ID: 11278986
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
    Niks D; Hilario E; Dierkers A; Ngo H; Borchardt D; Neubauer TJ; Fan L; Mueller LJ; Dunn MF
    Biochemistry; 2013 Sep; 52(37):6396-411. PubMed ID: 23952479
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
    Weyand M; Schlichting I; Herde P; Marabotti A; Mozzarelli A
    J Biol Chem; 2002 Mar; 277(12):10653-60. PubMed ID: 11756454
    [TBL] [Abstract][Full Text] [Related]  

  • 7. pH dependence of tryptophan synthase catalytic mechanism: I. The first stage, the beta-elimination reaction.
    Schiaretti F; Bettati S; Viappiani C; Mozzarelli A
    J Biol Chem; 2004 Jul; 279(28):29572-82. PubMed ID: 15117965
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the functional role of a flexible loop in the alpha-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis.
    Brzović PS; Hyde CC; Miles EW; Dunn MF
    Biochemistry; 1993 Oct; 32(39):10404-13. PubMed ID: 8399184
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence that mutations in a loop region of the alpha-subunit inhibit the transition from an open to a closed conformation in the tryptophan synthase bienzyme complex.
    Brzović PS; Sawa Y; Hyde CC; Miles EW; Dunn MF
    J Biol Chem; 1992 Jun; 267(18):13028-38. PubMed ID: 1618800
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tryptophan synthase: structure and function of the monovalent cation site.
    Dierkers AT; Niks D; Schlichting I; Dunn MF
    Biochemistry; 2009 Nov; 48(46):10997-1010. PubMed ID: 19848417
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational changes and subunit communication in tryptophan synthase: effect of substrates and substrate analogs.
    Strambini GB; Cioni P; Peracchi A; Mozzarelli A
    Biochemistry; 1992 Aug; 31(33):7535-42. PubMed ID: 1510940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.
    Ngo H; Harris R; Kimmich N; Casino P; Niks D; Blumenstein L; Barends TR; Kulik V; Weyand M; Schlichting I; Dunn MF
    Biochemistry; 2007 Jul; 46(26):7713-27. PubMed ID: 17559195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes.
    Ruvinov SB; Yang XJ; Parris KD; Banik U; Ahmed SA; Miles EW; Sackett DL
    J Biol Chem; 1995 Mar; 270(11):6357-69. PubMed ID: 7890774
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cooperative fluctuations and subunit communication in tryptophan synthase.
    Bahar I; Jernigan RL
    Biochemistry; 1999 Mar; 38(12):3478-90. PubMed ID: 10090734
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allosteric regulation of tryptophan synthase: effects of pH, temperature, and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate-L-serine intermediates.
    Peracchi A; Bettati S; Mozzarelli A; Rossi GL; Miles EW; Dunn MF
    Biochemistry; 1996 Feb; 35(6):1872-80. PubMed ID: 8639669
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thermal repair of tryptophan synthase mutations in a regulatory intersubunit salt bridge. Evidence from arrhenius plots, absorption spectra, and primary kinetic isotope effects.
    Fan YX; McPhie P; Miles EW
    J Biol Chem; 2000 Jul; 275(27):20302-7. PubMed ID: 10801803
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The tryptophan synthase alpha 2 beta 2 complex. Cleavage of a flexible loop in the alpha subunit alters allosteric properties.
    Miles EW
    J Biol Chem; 1991 Jun; 266(17):10715-8. PubMed ID: 1904055
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational changes in the alpha-subunit coupled to binding of the beta 2-subunit of tryptophan synthase from Escherichia coli: crystal structure of the tryptophan synthase alpha-subunit alone.
    Nishio K; Morimoto Y; Ishizuka M; Ogasahara K; Tsukihara T; Yutani K
    Biochemistry; 2005 Feb; 44(4):1184-92. PubMed ID: 15667212
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
    Rhee S; Parris KD; Hyde CC; Ahmed SA; Miles EW; Davies DR
    Biochemistry; 1997 Jun; 36(25):7664-80. PubMed ID: 9201907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase.
    Kulik V; Weyand M; Seidel R; Niks D; Arac D; Dunn MF; Schlichting I
    J Mol Biol; 2002 Dec; 324(4):677-90. PubMed ID: 12460570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.