336 related articles for article (PubMed ID: 15698764)
41. Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor.
Kadono S; Sakamoto A; Kikuchi Y; Oh-Eda M; Yabuta N; Yoshihashi K; Kitazawa T; Suzuki T; Koga T; Hattori K; Shiraishi T; Haramura M; Kodama H; Ono Y; Esaki T; Sato H; Watanabe Y; Itoh S; Ohta M; Kozono T
Biochem Biophys Res Commun; 2005 Jan; 326(4):859-65. PubMed ID: 15607748
[TBL] [Abstract][Full Text] [Related]
42. Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors.
Ishihara T; Seki N; Hirayama F; Orita M; Koshio H; Taniuchi Y; Sakai-Moritani Y; Iwatsuki Y; Kaku S; Kawasaki T; Matsumoto Y; Tsukamoto S
Bioorg Med Chem; 2007 Jun; 15(12):4175-92. PubMed ID: 17416533
[TBL] [Abstract][Full Text] [Related]
43. Factor VIIa inhibitors: gaining selectivity within the trypsin family.
Shrader WD; Kolesnikov A; Burgess-Henry J; Rai R; Hendrix J; Hu H; Torkelson S; Ton T; Young WB; Katz BA; Yu C; Tang J; Cabuslay R; Sanford E; Janc JW; Sprengeler PA
Bioorg Med Chem Lett; 2006 Mar; 16(6):1596-600. PubMed ID: 16413783
[TBL] [Abstract][Full Text] [Related]
44. Enhancing the anticoagulant potency of soluble tissue factor mutants by increasing their affinity to factor VIIa.
Yang J; Lee GF; Riederer MA; Kelley RF
Thromb Haemost; 2002 Mar; 87(3):450-8. PubMed ID: 11916078
[TBL] [Abstract][Full Text] [Related]
45. Hemextin AB complex, a unique anticoagulant protein complex from Hemachatus haemachatus (African Ringhals cobra) venom that inhibits clot initiation and factor VIIa activity.
Banerjee Y; Mizuguchi J; Iwanaga S; Kini RM
J Biol Chem; 2005 Dec; 280(52):42601-11. PubMed ID: 16204244
[TBL] [Abstract][Full Text] [Related]
46. Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors.
Priestley ES; Cheney DL; DeLucca I; Wei A; Luettgen JM; Rendina AR; Wong PC; Wexler RR
J Med Chem; 2015 Aug; 58(15):6225-36. PubMed ID: 26151189
[TBL] [Abstract][Full Text] [Related]
47. A new type of thrombin inhibitor, noncytotoxic phospholipase A2, from the Naja haje cobra venom.
Osipov AV; Filkin SY; Makarova YV; Tsetlin VI; Utkin YN
Toxicon; 2010; 55(2-3):186-94. PubMed ID: 19622365
[TBL] [Abstract][Full Text] [Related]
48. Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.
Huang H; Norledge BV; Liu C; Olson AJ; Edgington TS
Biochemistry; 2003 Sep; 42(36):10619-26. PubMed ID: 12962485
[TBL] [Abstract][Full Text] [Related]
49. Approaches to selective peptidic inhibitors of factor Xa.
Bromfield KM; Quinsey NS; Duggan PJ; Pike RN
Chem Biol Drug Des; 2006 Jul; 68(1):11-9. PubMed ID: 16923021
[TBL] [Abstract][Full Text] [Related]
50. Lipid-bound factor Xa regulates tissue factor activity.
Hathcock J; Rusinova E; Vaananen H; Nemerson Y
Biochemistry; 2007 May; 46(20):6134-40. PubMed ID: 17469850
[TBL] [Abstract][Full Text] [Related]
51. Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases.
Abel R; Salam NK; Shelley J; Farid R; Friesner RA; Sherman W
ChemMedChem; 2011 Jun; 6(6):1049-66. PubMed ID: 21506273
[TBL] [Abstract][Full Text] [Related]
52. Discovery of a novel, potent, and specific family of factor Xa inhibitors via combinatorial chemistry.
Ostrem JA; al-Obeidi F; Safar P; Safarova A; Stringer SK; Patek M; Cross MT; Spoonamore J; LoCascio JC; Kasireddy P; Thorpe DS; Sepetov N; Lebl M; Wildgoose P; Strop P
Biochemistry; 1998 Jan; 37(4):1053-9. PubMed ID: 9454596
[TBL] [Abstract][Full Text] [Related]
53. Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor.
Kadono S; Sakamoto A; Kikuchi Y; Oh-eda M; Yabuta N; Koga T; Hattori K; Shiraishi T; Haramura M; Kodama H; Esaki T; Sato H; Watanabe Y; Itoh S; Ohta M; Kozono T
Biochem Biophys Res Commun; 2004 Nov; 324(4):1227-33. PubMed ID: 15504346
[TBL] [Abstract][Full Text] [Related]
54. Approaches in anticoagulation: rationales for target positioning.
Wieland HA; Laux V; Kozian D; Lorenz M
Curr Opin Investig Drugs; 2003 Mar; 4(3):264-71. PubMed ID: 12735227
[TBL] [Abstract][Full Text] [Related]
55. Studies of the factor Xa-dependent inhibitor of factor VIIa/tissue factor (extrinsic pathway inhibitor) from cell supernates of cultured human umbilical vein endothelial cells.
Warn-Cramer BJ; Almus FE; Rapaport SI
Thromb Haemost; 1989 Feb; 61(1):101-5. PubMed ID: 2665164
[TBL] [Abstract][Full Text] [Related]
56. Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.
Kochanny MJ; Adler M; Ewing J; Griedel BD; Ho E; Karanjawala R; Lee W; Lentz D; Liang AM; Morrissey MM; Phillips GB; Post J; Sacchi KL; Sakata ST; Subramanyam B; Vergona R; Walters J; White KA; Whitlow M; Ye B; Zhao Z; Shaw KJ
Bioorg Med Chem; 2007 Mar; 15(5):2127-46. PubMed ID: 17227710
[TBL] [Abstract][Full Text] [Related]
57. Sulfonamidopyrrolidinone factor Xa inhibitors: potency and selectivity enhancements via P-1 and P-4 optimization.
Choi-Sledeski YM; McGarry DG; Green DM; Mason HJ; Becker MR; Davis RS; Ewing WR; Dankulich WP; Manetta VE; Morris RL; Spada AP; Cheney DL; Brown KD; Colussi DJ; Chu V; Heran CL; Morgan SR; Bentley RG; Leadley RJ; Maignan S; Guilloteau JP; Dunwiddie CT; Pauls HW
J Med Chem; 1999 Sep; 42(18):3572-87. PubMed ID: 10479289
[TBL] [Abstract][Full Text] [Related]
58. Inhibition of tissue factor-factor VIIa-catalyzed factor X activation by factor Xa-tissue factor pathway inhibitor. A rotating disc study on the effect of phospholipid membrane composition.
Salemink I; Franssen J; Willems GM; Hemker HC; Lindhout T
J Biol Chem; 1999 Oct; 274(40):28225-32. PubMed ID: 10497177
[TBL] [Abstract][Full Text] [Related]
59. III. Instantaneous inhibition by compound 48/80 of tissue factor-initiated extrinsic coagulation is mediated by the downregulation of factor VII activation.
Chu AJ; Wang ZG; Fox MJ
Arch Biochem Biophys; 2000 May; 377(2):357-65. PubMed ID: 10845714
[TBL] [Abstract][Full Text] [Related]
60. Synthesis and crystal structures of substituted benzenes and benzoquinones as tissue factor VIIa inhibitors.
Parlow JJ; Stevens AM; Stegeman RA; Stallings WC; Kurumbail RG; South MS
J Med Chem; 2003 Sep; 46(20):4297-312. PubMed ID: 13678408
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]