1059 related articles for article (PubMed ID: 15703193)
1. SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.
Le TT; Pham LT; Butchbach ME; Zhang HL; Monani UR; Coovert DD; Gavrilina TO; Xing L; Bassell GJ; Burghes AH
Hum Mol Genet; 2005 Mar; 14(6):845-57. PubMed ID: 15703193
[TBL] [Abstract][Full Text] [Related]
2. Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy.
El-Khodor BF; Edgar N; Chen A; Winberg ML; Joyce C; Brunner D; Suárez-Fariñas M; Heyes MP
Exp Neurol; 2008 Jul; 212(1):29-43. PubMed ID: 18455159
[TBL] [Abstract][Full Text] [Related]
3. Molecular and functional analysis of intragenic SMN1 mutations in patients with spinal muscular atrophy.
Sun Y; Grimmler M; Schwarzer V; Schoenen F; Fischer U; Wirth B
Hum Mutat; 2005 Jan; 25(1):64-71. PubMed ID: 15580564
[TBL] [Abstract][Full Text] [Related]
4. Induction of full-length survival motor neuron by polyphenol botanical compounds.
Sakla MS; Lorson CL
Hum Genet; 2008 Jan; 122(6):635-43. PubMed ID: 17962980
[TBL] [Abstract][Full Text] [Related]
5. Implication of fetal SMN2 expression in type I SMA pathogenesis: protection or pathological gain of function?
Soler-Botija C; Cuscó I; Caselles L; López E; Baiget M; Tizzano EF
J Neuropathol Exp Neurol; 2005 Mar; 64(3):215-23. PubMed ID: 15804053
[TBL] [Abstract][Full Text] [Related]
6. A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels.
Wolstencroft EC; Mattis V; Bajer AA; Young PJ; Lorson CL
Hum Mol Genet; 2005 May; 14(9):1199-210. PubMed ID: 15790598
[TBL] [Abstract][Full Text] [Related]
7. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Monani UR; Sendtner M; Coovert DD; Parsons DW; Andreassi C; Le TT; Jablonka S; Schrank B; Rossoll W; Prior TW; Morris GE; Burghes AH
Hum Mol Genet; 2000 Feb; 9(3):333-9. PubMed ID: 10655541
[TBL] [Abstract][Full Text] [Related]
8. Novel aminoglycosides increase SMN levels in spinal muscular atrophy fibroblasts.
Mattis VB; Rai R; Wang J; Chang CW; Coady T; Lorson CL
Hum Genet; 2006 Nov; 120(4):589-601. PubMed ID: 16951947
[TBL] [Abstract][Full Text] [Related]
9. Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect.
Gavrilina TO; McGovern VL; Workman E; Crawford TO; Gogliotti RG; DiDonato CJ; Monani UR; Morris GE; Burghes AH
Hum Mol Genet; 2008 Apr; 17(8):1063-75. PubMed ID: 18178576
[TBL] [Abstract][Full Text] [Related]
10. A sensitive assay for measuring SMN mRNA levels in peripheral blood and in muscle samples of patients affected with spinal muscular atrophy.
Vezain M; Saugier-Veber P; Melki J; Toutain A; Bieth E; Husson M; Pedespan JM; Viollet L; Pénisson-Besnier I; Fehrenbach S; Bou J; Frébourg T; Tosi M
Eur J Hum Genet; 2007 Oct; 15(10):1054-62. PubMed ID: 17609673
[TBL] [Abstract][Full Text] [Related]
11. 5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
Yuo CY; Lin HH; Chang YS; Yang WK; Chang JG
Ann Neurol; 2008 Jan; 63(1):26-34. PubMed ID: 17924536
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.
Thurmond J; Butchbach ME; Palomo M; Pease B; Rao M; Bedell L; Keyvan M; Pai G; Mishra R; Haraldsson M; Andresson T; Bragason G; Thosteinsdottir M; Bjornsson JM; Coovert DD; Burghes AH; Gurney ME; Singh J
J Med Chem; 2008 Feb; 51(3):449-69. PubMed ID: 18205293
[TBL] [Abstract][Full Text] [Related]
13. Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells.
Grzeschik SM; Ganta M; Prior TW; Heavlin WD; Wang CH
Ann Neurol; 2005 Aug; 58(2):194-202. PubMed ID: 16049920
[TBL] [Abstract][Full Text] [Related]
14. hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.
Hofmann Y; Wirth B
Hum Mol Genet; 2002 Aug; 11(17):2037-49. PubMed ID: 12165565
[TBL] [Abstract][Full Text] [Related]
15. A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.
Monani UR; Lorson CL; Parsons DW; Prior TW; Androphy EJ; Burghes AH; McPherson JD
Hum Mol Genet; 1999 Jul; 8(7):1177-83. PubMed ID: 10369862
[TBL] [Abstract][Full Text] [Related]
16. A SMNDelta7 read-through product confers functionality to the SMNDelta7 protein.
Mattis VB; Bowerman M; Kothary R; Lorson CL
Neurosci Lett; 2008 Sep; 442(1):54-8. PubMed ID: 18601974
[TBL] [Abstract][Full Text] [Related]
17. Stimulating full-length SMN2 expression by delivering bifunctional RNAs via a viral vector.
Baughan T; Shababi M; Coady TH; Dickson AM; Tullis GE; Lorson CL
Mol Ther; 2006 Jul; 14(1):54-62. PubMed ID: 16580882
[TBL] [Abstract][Full Text] [Related]
18. Salbutamol increases SMN mRNA and protein levels in spinal muscular atrophy cells.
Angelozzi C; Borgo F; Tiziano FD; Martella A; Neri G; Brahe C
J Med Genet; 2008 Jan; 45(1):29-31. PubMed ID: 17932121
[TBL] [Abstract][Full Text] [Related]
19. Therapeutics development for spinal muscular atrophy.
Sumner CJ
NeuroRx; 2006 Apr; 3(2):235-45. PubMed ID: 16554261
[TBL] [Abstract][Full Text] [Related]
20. SMN transcript stability: could modulation of messenger RNA degradation provide a novel therapy for spinal muscular atrophy?
Heier CR; Gogliotti RG; DiDonato CJ
J Child Neurol; 2007 Aug; 22(8):1013-8. PubMed ID: 17761657
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
