BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 15705582)

  • 41. The effect of cotinine or cigarette smoke co-administration on the formation of O6-methylguanine adducts in the lung and liver of A/J mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Brown BG; Chang CJ; Ayres PH; Lee CK; Doolittle DJ
    Toxicol Sci; 1999 Jan; 47(1):33-9. PubMed ID: 10048151
    [TBL] [Abstract][Full Text] [Related]  

  • 42. The tobacco-specific carcinogen NNK induces pulmonary tumorigenesis via nAChR/Src/STAT3-mediated activation of the renin-angiotensin system and IGF-1R signaling.
    Boo HJ; Min HY; Hwang SJ; Lee HJ; Lee JW; Oh SR; Park CS; Park JS; Lee YM; Lee HY
    Exp Mol Med; 2023 Jun; 55(6):1131-1144. PubMed ID: 37258578
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Apigenin inhibits NNK-induced focal adhesion kinase activation in pancreatic cancer cells.
    Pham H; Chen M; Takahashi H; King J; Reber HA; Hines OJ; Pandol S; Eibl G
    Pancreas; 2012 Nov; 41(8):1306-15. PubMed ID: 22889981
    [TBL] [Abstract][Full Text] [Related]  

  • 44. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway.
    Hung YH; Hung WC
    Chem Biol Interact; 2009 May; 179(2-3):154-9. PubMed ID: 19027725
    [TBL] [Abstract][Full Text] [Related]  

  • 45. The Proto-oncogene PKCι regulates the alternative splicing of Bcl-x pre-mRNA.
    Shultz JC; Vu N; Shultz MD; Mba MU; Shapiro BA; Chalfant CE
    Mol Cancer Res; 2012 May; 10(5):660-9. PubMed ID: 22522453
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K; Trushin N; Hecht SS; Stoner GD
    Carcinogenesis; 1991 Jun; 12(6):1029-34. PubMed ID: 2044181
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Protein kinase C
    Kenchappa RS; Liu Y; Argenziano MG; Banu MA; Mladek AC; West R; Luu A; Quiñones-Hinojosa A; Hambardzumyan D; Justilien V; Leitges M; Sarkaria JN; Sims PA; Canoll P; Murray NR; Fields AP; Rosenfeld SS
    Cell Rep; 2021 Nov; 37(8):110054. PubMed ID: 34818553
    [TBL] [Abstract][Full Text] [Related]  

  • 48. A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion.
    Butler AM; Scotti Buzhardt ML; Erdogan E; Li S; Inman KS; Fields AP; Murray NR
    Oncotarget; 2015 Jun; 6(17):15297-310. PubMed ID: 25915428
    [TBL] [Abstract][Full Text] [Related]  

  • 49. γ-H2AX is a sensitive marker of DNA damage induced by metabolically activated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Ibuki Y; Shikata M; Toyooka T
    Toxicol In Vitro; 2015 Oct; 29(7):1831-8. PubMed ID: 26231820
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ; Liao AM; Liu Y; Jones AB; Anderson LM; Yang CS
    Carcinogenesis; 1997 Aug; 18(8):1577-84. PubMed ID: 9276633
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Metabolism and DNA damage induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in fetal tissues of the Syrian golden hamster.
    Rossignol G; Alaoui-Jamali MA; Castonguay A; Schuller HM
    Cancer Res; 1989 Oct; 49(20):5671-6. PubMed ID: 2790785
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR; Ding X; Murphy SE
    Drug Metab Dispos; 2003 Oct; 31(10):1199-202. PubMed ID: 12975327
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung.
    Atalla A; Maser E
    Toxicology; 1999 Nov; 139(1-2):155-66. PubMed ID: 10614696
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG; Borukhova A; Akerkar SA; Hecht SS
    Cancer Epidemiol Biomarkers Prev; 1997 Feb; 6(2):113-20. PubMed ID: 9037562
    [TBL] [Abstract][Full Text] [Related]  

  • 55. The oncogenic role of PKCiota gene amplification and overexpression in Chinese non-small cell lung cancer.
    Luo Q; Tang L; Lin H; Huang J; Zhang T; Liu Y; Wang J; Zhan P; Yin X; Su X; Ji Q; Yu D; Xu L
    Lung Cancer; 2014 May; 84(2):190-5. PubMed ID: 24636699
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism.
    Phillips E; Lang V; Bohlen J; Bethke F; Puccio L; Tichy D; Herold-Mende C; Hielscher T; Lichter P; Goidts V
    Int J Cancer; 2016 Oct; 139(8):1776-87. PubMed ID: 27299852
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells.
    Wald FA; Oriolo AS; Mashukova A; Fregien NL; Langshaw AH; Salas PJ
    J Cell Sci; 2008 Mar; 121(Pt 5):644-54. PubMed ID: 18270268
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
    Liu LL; Alaoui-Jamali MA; el Alami N; Castonguay A
    Cancer Res; 1990 Mar; 50(6):1810-6. PubMed ID: 2306734
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer.
    Fields AP; Frederick LA; Regala RP
    Biochem Soc Trans; 2007 Nov; 35(Pt 5):996-1000. PubMed ID: 17956262
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Nicotine inactivation of the proapoptotic function of Bax through phosphorylation.
    Xin M; Deng X
    J Biol Chem; 2005 Mar; 280(11):10781-9. PubMed ID: 15642728
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.