BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 15709745)

  • 1. Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.
    McCourt JA; Pang SS; Guddat LW; Duggleby RG
    Biochemistry; 2005 Feb; 44(7):2330-8. PubMed ID: 15709745
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
    Wang JG; Lee PK; Dong YH; Pang SS; Duggleby RG; Li ZM; Guddat LW
    FEBS J; 2009 Mar; 276(5):1282-90. PubMed ID: 19187232
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.
    Pang SS; Duggleby RG; Guddat LW
    J Mol Biol; 2002 Mar; 317(2):249-62. PubMed ID: 11902841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides.
    Garcia MD; Wang JG; Lonhienne T; Guddat LW
    FEBS J; 2017 Jul; 284(13):2037-2051. PubMed ID: 28485824
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families.
    Garcia MD; Nouwens A; Lonhienne TG; Guddat LW
    Proc Natl Acad Sci U S A; 2017 Feb; 114(7):E1091-E1100. PubMed ID: 28137884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme.
    Tittmann K; Schröder K; Golbik R; McCourt J; Kaplun A; Duggleby RG; Barak Z; Chipman DM; Hübner G
    Biochemistry; 2004 Jul; 43(27):8652-61. PubMed ID: 15236573
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural insights into the mechanism of inhibition of AHAS by herbicides.
    Lonhienne T; Garcia MD; Pierens G; Mobli M; Nouwens A; Guddat LW
    Proc Natl Acad Sci U S A; 2018 Feb; 115(9):E1945-E1954. PubMed ID: 29440497
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase.
    McCourt JA; Pang SS; King-Scott J; Guddat LW; Duggleby RG
    Proc Natl Acad Sci U S A; 2006 Jan; 103(3):569-73. PubMed ID: 16407096
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
    Pham NC; Moon JY; Cho JH; Lee SJ; Park JS; Kim DE; Park Y; Yoon MY
    Biosci Biotechnol Biochem; 2010; 74(11):2281-6. PubMed ID: 21071847
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate.
    Pang SS; Duggleby RG; Schowen RL; Guddat LW
    J Biol Chem; 2004 Jan; 279(3):2242-53. PubMed ID: 14557277
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and mechanism of inhibition of plant acetohydroxyacid synthase.
    Duggleby RG; McCourt JA; Guddat LW
    Plant Physiol Biochem; 2008 Mar; 46(3):309-24. PubMed ID: 18234503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationships for a new family of sulfonylurea herbicides.
    Wang JG; Li ZM; Ma N; Wang BL; Jiang L; Pang SS; Lee YT; Guddat LW; Duggleby RG
    J Comput Aided Mol Des; 2005 Nov; 19(11):801-20. PubMed ID: 16374672
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl.
    Pang SS; Guddat LW; Duggleby RG
    Acta Crystallogr D Biol Crystallogr; 2004 Jan; 60(Pt 1):153-5. PubMed ID: 14684914
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acetohydroxyacid synthase: a target for antimicrobial drug discovery.
    Pue N; Guddat LW
    Curr Pharm Des; 2014; 20(5):740-53. PubMed ID: 23688082
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements.
    Lonhienne T; Garcia MD; Fraser JA; Williams CM; Guddat LW
    PLoS One; 2017; 12(2):e0171443. PubMed ID: 28178302
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I.
    Belenky I; Steinmetz A; Vyazmensky M; Barak Z; Tittmann K; Chipman DM
    FEBS J; 2012 Jun; 279(11):1967-79. PubMed ID: 22443469
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of a highly conserved proline-126 in ThDP binding of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA; Gedi V; Lee SC; Koh SH; Yoon MY
    Enzyme Microb Technol; 2013 Sep; 53(4):243-9. PubMed ID: 23931689
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding and activation of thiamin diphosphate in acetohydroxyacid synthase.
    Bar-Ilan A; Balan V; Tittmann K; Golbik R; Vyazmensky M; Hübner G; Barak Z; Chipman DM
    Biochemistry; 2001 Oct; 40(39):11946-54. PubMed ID: 11570896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutagenesis of Escherichia coli acetohydroxyacid synthase isoenzyme II and characterization of three herbicide-insensitive forms.
    Hill CM; Duggleby RG
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):653-61. PubMed ID: 9794808
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and functional evaluation of three well-conserved serine residues in tobacco acetohydroxyacid synthase.
    Yoon MY; Gedi V; Kim J; Park Y; Kim DE; Park EH; Choi JD
    Biochimie; 2010 Jan; 92(1):65-70. PubMed ID: 19825392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.