These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 15713403)

  • 21. Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxoimidazolidin-4-ones: characterization of new CB1 cannabinoid receptor inverse agonists/antagonists.
    Muccioli GG; Wouters J; Charlier C; Scriba GK; Pizza T; Di Pace P; De Martino P; Poppitz W; Poupaert JH; Lambert DM
    J Med Chem; 2006 Feb; 49(3):872-82. PubMed ID: 16451053
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists.
    Pettersson H; Bülow A; Ek F; Jensen J; Ottesen LK; Fejzic A; Ma JN; Del Tredici AL; Currier EA; Gardell LR; Tabatabaei A; Craig D; McFarland K; Ott TR; Piu F; Burstein ES; Olsson R
    J Med Chem; 2009 Apr; 52(7):1975-82. PubMed ID: 19338356
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Novel thioamide derivatives as neutral CB1 receptor antagonists.
    Boström J; Olsson RI; Tholander J; Greasley PJ; Ryberg E; Nordberg H; Hjorth S; Cheng L
    Bioorg Med Chem Lett; 2010 Jan; 20(2):479-82. PubMed ID: 20005704
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands.
    Silvestri R; Ligresti A; La Regina G; Piscitelli F; Gatti V; Lavecchia A; Brizzi A; Pasquini S; Allarà M; Fantini N; Carai MA; Bigogno C; Rozio MG; Sinisi R; Novellino E; Colombo G; Di Marzo V; Dondio G; Corelli F
    Eur J Med Chem; 2010 Dec; 45(12):5878-86. PubMed ID: 20943290
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery of imidazole carboxamides as potent and selective CCK1R agonists.
    Zhu C; Hansen AR; Bateman T; Chen Z; Holt TG; Hubert JA; Karanam BV; Lee SJ; Pan J; Qian S; Reddy VB; Reitman ML; Strack AM; Tong V; Weingarth DT; Wolff MS; MacNeil DJ; Weber AE; Duffy JL; Edmondson SD
    Bioorg Med Chem Lett; 2008 Aug; 18(15):4393-6. PubMed ID: 18614364
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and evaluation of new arylsulfonamidomethylcyclohexyl derivatives as human neuropeptide Y Y5 receptor antagonists for the treatment of obesity.
    Moreno A; Pérez S; Galiano S; Juanenea L; Erviti O; Frígola C; Aldana I; Monge A
    Eur J Med Chem; 2004 Jan; 39(1):49-58. PubMed ID: 14987833
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biarylpyrazolyl oxadiazole as potent, selective, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
    Lee SH; Seo HJ; Lee SH; Jung ME; Park JH; Park HJ; Yoo J; Yun H; Na J; Kang SY; Song KS; Kim MA; Chang CH; Kim J; Lee J
    J Med Chem; 2008 Nov; 51(22):7216-33. PubMed ID: 18954042
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.
    Muccioli GG; Wouters J; Scriba GK; Poppitz W; Poupaert JH; Lambert DM
    J Med Chem; 2005 Nov; 48(23):7486-90. PubMed ID: 16279809
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Furo[2,3-b]pyridine-based cannabinoid-1 receptor inverse agonists: synthesis and biological evaluation. Part 1.
    Debenham JS; Madsen-Duggan CB; Toupence RB; Walsh TF; Wang J; Tong X; Kumar S; Lao J; Fong TM; Xiao JC; Huang CR; Shen CP; Feng Y; Marsh DJ; Stribling DS; Shearman LP; Strack AM; Goulet MT
    Bioorg Med Chem Lett; 2010 Feb; 20(4):1448-52. PubMed ID: 20096577
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Suppression of food intake and food-reinforced behavior produced by the novel CB1 receptor antagonist/inverse agonist AM 1387.
    McLaughlin PJ; Qian L; Wood JT; Wisniecki A; Winston KM; Swezey LA; Ishiwari K; Betz AJ; Pandarinathan L; Xu W; Makriyannis A; Salamone JD
    Pharmacol Biochem Behav; 2006 Mar; 83(3):396-402. PubMed ID: 16616951
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice.
    Wu CH; Hung MS; Song JS; Yeh TK; Chou MC; Chu CM; Jan JJ; Hsieh MT; Tseng SL; Chang CP; Hsieh WP; Lin Y; Yeh YN; Chung WL; Kuo CW; Lin CY; Shy HS; Chao YS; Shia KS
    J Med Chem; 2009 Jul; 52(14):4496-510. PubMed ID: 19530697
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis of functionalized 1,8-naphthyridinones and their evaluation as novel, orally active CB1 receptor inverse agonists.
    Debenham JS; Madsen-Duggan CB; Walsh TF; Wang J; Tong X; Doss GA; Lao J; Fong TM; Schaeffer MT; Xiao JC; Huang CR; Shen CP; Feng Y; Marsh DJ; Stribling DS; Shearman LP; Strack AM; MacIntyre DE; Van der Ploeg LH; Goulet MT
    Bioorg Med Chem Lett; 2006 Feb; 16(3):681-5. PubMed ID: 16263284
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
    Frost JM; Dart MJ; Tietje KR; Garrison TR; Grayson GK; Daza AV; El-Kouhen OF; Miller LN; Li L; Yao BB; Hsieh GC; Pai M; Zhu CZ; Chandran P; Meyer MD
    J Med Chem; 2008 Mar; 51(6):1904-12. PubMed ID: 18311894
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists.
    Gillman KW; Higgins MA; Poindexter GS; Browning M; Clarke WJ; Flowers S; Grace JE; Hogan JB; McGovern RT; Iben LG; Mattson GK; Ortiz A; Rassnick S; Russell JW; Antal-Zimanyi I
    Bioorg Med Chem; 2006 Aug; 14(16):5517-26. PubMed ID: 16697206
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists.
    Armstrong HE; Galka A; Lin LS; Lanza TJ; Jewell JP; Shah SK; Guthikonda R; Truong Q; Chang LL; Quaker G; Colandrea VJ; Tong X; Wang J; Xu S; Fong TM; Shen CP; Lao J; Chen J; Shearman LP; Stribling DS; Rosko K; Strack A; Ha S; Van der Ploeg L; Goulet MT; Hagmann WK
    Bioorg Med Chem Lett; 2007 Apr; 17(8):2184-7. PubMed ID: 17293109
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB1 cannabinoid receptor ligands: synthesis and pharmacological evaluation.
    Muccioli GG; Martin D; Scriba GK; Poppitz W; Poupaert JH; Wouters J; Lambert DM
    J Med Chem; 2005 Apr; 48(7):2509-17. PubMed ID: 15801840
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series.
    Ellsworth BA; Wang Y; Zhu Y; Pendri A; Gerritz SW; Sun C; Carlson KE; Kang L; Baska RA; Yang Y; Huang Q; Burford NT; Cullen MJ; Johnghar S; Behnia K; Pelleymounter MA; Washburn WN; Ewing WR
    Bioorg Med Chem Lett; 2007 Jul; 17(14):3978-82. PubMed ID: 17513109
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and pharmacological evaluation of coumarin derivatives as cannabinoid receptor antagonists and inverse agonists.
    Behrenswerth A; Volz N; Toräng J; Hinz S; Bräse S; Müller CE
    Bioorg Med Chem; 2009 Apr; 17(7):2842-51. PubMed ID: 19278853
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.
    Stern E; Muccioli GG; Millet R; Goossens JF; Farce A; Chavatte P; Poupaert JH; Lambert DM; Depreux P; Hénichart JP
    J Med Chem; 2006 Jan; 49(1):70-9. PubMed ID: 16392793
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery of a novel class of selective human CB1 inverse agonists.
    Foloppe N; Allen NH; Bentley CH; Brooks TD; Kennett G; Knight AR; Leonardi S; Misra A; Monck NJ; Sellwood DM
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1199-206. PubMed ID: 18083560
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.