BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 15713898)

  • 1. Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.
    DeFeo-Jones D; Barnett SF; Fu S; Hancock PJ; Haskell KM; Leander KR; McAvoy E; Robinson RG; Duggan ME; Lindsley CW; Zhao Z; Huber HE; Jones RE
    Mol Cancer Ther; 2005 Feb; 4(2):271-9. PubMed ID: 15713898
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.
    Okano J; Gaslightwala I; Birnbaum MJ; Rustgi AK; Nakagawa H
    J Biol Chem; 2000 Oct; 275(40):30934-42. PubMed ID: 10908564
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
    Nakamura JL; Karlsson A; Arvold ND; Gottschalk AR; Pieper RO; Stokoe D; Haas-Kogan DA
    J Neurooncol; 2005 Feb; 71(3):215-22. PubMed ID: 15735908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.
    Takeuchi H; Kondo Y; Fujiwara K; Kanzawa T; Aoki H; Mills GB; Kondo S
    Cancer Res; 2005 Apr; 65(8):3336-46. PubMed ID: 15833867
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The activation of Akt/PKB signaling pathway and cell survival.
    Song G; Ouyang G; Bao S
    J Cell Mol Med; 2005; 9(1):59-71. PubMed ID: 15784165
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN; Easton J; Huang S; Veverka KA; Germain GS; Harwood FC; Houghton PJ
    Cancer Res; 2003 Jan; 63(2):364-74. PubMed ID: 12543789
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein kinase B/Akt regulates coxsackievirus B3 replication through a mechanism which is not caspase dependent.
    Esfandiarei M; Luo H; Yanagawa B; Suarez A; Dabiri D; Zhang J; McManus BM
    J Virol; 2004 Apr; 78(8):4289-98. PubMed ID: 15047842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S; Hussain AR; Al-Hussein KA; Manogaran PS; Wickrema A; Gutierrez MI; Bhatia KG
    Clin Cancer Res; 2005 Apr; 11(8):3102-8. PubMed ID: 15837766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
    Stoica GE; Franke TF; Wellstein A; Czubayko F; List HJ; Reiter R; Morgan E; Martin MB; Stoica A
    Mol Endocrinol; 2003 May; 17(5):818-30. PubMed ID: 12554767
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The protein kinase B/Akt signalling pathway in human malignancy.
    Nicholson KM; Anderson NG
    Cell Signal; 2002 May; 14(5):381-95. PubMed ID: 11882383
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM; Tazzari PL; Tabellini G; Bortul R; Billi AM; Manzoli L; Ruggeri A; Conte R; Cocco L
    Leukemia; 2003 Sep; 17(9):1794-805. PubMed ID: 12970779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors.
    Barnett SF; Defeo-Jones D; Fu S; Hancock PJ; Haskell KM; Jones RE; Kahana JA; Kral AM; Leander K; Lee LL; Malinowski J; McAvoy EM; Nahas DD; Robinson RG; Huber HE
    Biochem J; 2005 Jan; 385(Pt 2):399-408. PubMed ID: 15456405
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs.
    Yanagihara M; Katano M; Takahashi-Sasaki N; Kimata K; Taira K; Andoh T
    Cancer Sci; 2005 Sep; 96(9):620-6. PubMed ID: 16128748
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional and therapeutic significance of Akt deregulation in malignant melanoma.
    Robertson GP
    Cancer Metastasis Rev; 2005 Jun; 24(2):273-85. PubMed ID: 15986137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer.
    Chen X; Thakkar H; Tyan F; Gim S; Robinson H; Lee C; Pandey SK; Nwokorie C; Onwudiwe N; Srivastava RK
    Oncogene; 2001 Sep; 20(42):6073-83. PubMed ID: 11593415
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation.
    Faridi J; Fawcett J; Wang L; Roth RA
    Am J Physiol Endocrinol Metab; 2003 Nov; 285(5):E964-72. PubMed ID: 12876075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.
    Yuan ZQ; Sun M; Feldman RI; Wang G; Ma X; Jiang C; Coppola D; Nicosia SV; Cheng JQ
    Oncogene; 2000 May; 19(19):2324-30. PubMed ID: 10822383
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.
    Garofalo RS; Orena SJ; Rafidi K; Torchia AJ; Stock JL; Hildebrandt AL; Coskran T; Black SC; Brees DJ; Wicks JR; McNeish JD; Coleman KG
    J Clin Invest; 2003 Jul; 112(2):197-208. PubMed ID: 12843127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway.
    Poh TW; Pervaiz S
    Cancer Res; 2005 Jul; 65(14):6264-74. PubMed ID: 16024628
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
    Tsurutani J; West KA; Sayyah J; Gills JJ; Dennis PA
    Cancer Res; 2005 Sep; 65(18):8423-32. PubMed ID: 16166321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.