BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 15726176)

  • 1. Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.
    Sorensen JL; Sleeman MC; Schofield CJ
    Chem Commun (Camb); 2005 Mar; (9):1155-7. PubMed ID: 15726176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.
    Sleeman MC; Sorensen JL; Batchelar ET; McDonough MA; Schofield CJ
    J Biol Chem; 2005 Oct; 280(41):34956-65. PubMed ID: 16096274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
    Sleeman MC; Schofield CJ
    J Biol Chem; 2004 Feb; 279(8):6730-6. PubMed ID: 14625287
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carboxymethylproline synthase from Pectobacterium carotorova: a multifaceted member of the crotonase superfamily.
    Gerratana B; Arnett SO; Stapon A; Townsend CA
    Biochemistry; 2004 Dec; 43(50):15936-45. PubMed ID: 15595850
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.
    Ducho C; Hamed RB; Batchelar ET; Sorensen JL; Odell B; Schofield CJ
    Org Biomol Chem; 2009 Jul; 7(13):2770-9. PubMed ID: 19532994
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crotonase catalysis enables flexible production of functionalized prolines and carbapenams.
    Hamed RB; Henry L; Gomez-Castellanos JR; Mecinović J; Ducho C; Sorensen JL; Claridge TD; Schofield CJ
    J Am Chem Soc; 2012 Jan; 134(1):471-9. PubMed ID: 22091817
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.
    Hamed RB; Mecinović J; Ducho C; Claridge TD; Schofield CJ
    Chem Commun (Camb); 2010 Mar; 46(9):1413-5. PubMed ID: 20162132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and use of N, N-di-Boc-glutamate gamma-semialdehydes and related aldehydes.
    Constantinou-Kokotou V; Magrioti V
    Amino Acids; 2003 Apr; 24(3):231-43. PubMed ID: 12707805
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem.
    Stapon A; Li R; Townsend CA
    J Am Chem Soc; 2003 Dec; 125(51):15746-7. PubMed ID: 14677956
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).
    Sleeman MC; Smith P; Kellam B; Chhabra SR; Bycroft BW; Schofield CJ
    Chembiochem; 2004 Jun; 5(6):879-82. PubMed ID: 15174175
    [No Abstract]   [Full Text] [Related]  

  • 11. Two separate and distinct syntheses of stereospecifically deuteriated samples of (2S)-proline.
    Barraclough P; Dieterich P; Spray CA; Young DW
    Org Biomol Chem; 2006 Apr; 4(8):1483-91. PubMed ID: 16604215
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Definition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesis.
    Bodner MJ; Li R; Phelan RM; Freeman MF; Moshos KA; Lloyd EP; Townsend CA
    Chembiochem; 2011 Sep; 12(14):2159-65. PubMed ID: 21913298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A unique pathway for the 3-aminobutyrate starter unit from L-glutamate through β-glutamate during biosynthesis of the 24-membered macrolactam antibiotic, incednine.
    Takaishi M; Kudo F; Eguchi T
    Org Lett; 2012 Sep; 14(17):4591-3. PubMed ID: 22928983
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stereochemistry of the macrocyclization and elimination steps in taxadiene biosynthesis through deuterium labeling.
    Jin Q; Williams DC; Hezari M; Croteau R; Coates RM
    J Org Chem; 2005 Jun; 70(12):4667-75. PubMed ID: 15932303
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of benzylsuccinate synthase: stereochemistry of toluene addition to fumarate and maleate.
    Qiao C; Marsh EN
    J Am Chem Soc; 2005 Jun; 127(24):8608-9. PubMed ID: 15954762
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of stereoarray isotope labeled (SAIL) lysine via the "head-to-tail" conversion of SAIL glutamic acid.
    Terauchi T; Kamikawai T; Vinogradov MG; Starodubtseva EV; Takeda M; Kainosho M
    Org Lett; 2011 Jan; 13(1):161-3. PubMed ID: 21121622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline.
    Stapon A; Li R; Townsend CA
    J Am Chem Soc; 2003 Jul; 125(28):8486-93. PubMed ID: 12848554
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deuterium isotope effect on 13C chemical shifts of tetrabutylammonium salts of Schiff bases amino acids.
    Rozwadowski Z
    Magn Reson Chem; 2006 Sep; 44(9):881-6. PubMed ID: 16741983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis.
    Scholte AA; Vederas JC
    Org Biomol Chem; 2006 Feb; 4(4):730-42. PubMed ID: 16467948
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of glutamate 243 in the active site of 2-deoxy-scyllo-inosose synthase from Bacillus circulans.
    Hirayama T; Kudo F; Huang Z; Eguchi T
    Bioorg Med Chem; 2007 Jan; 15(1):418-23. PubMed ID: 17035031
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.