BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1115 related articles for article (PubMed ID: 15726367)

  • 1. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
    Hayward RL; Schornagel QC; Tente R; Macpherson JS; Aird RE; Guichard S; Habtemariam A; Sadler P; Jodrell DI
    Cancer Chemother Pharmacol; 2005 Jun; 55(6):577-83. PubMed ID: 15726367
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.
    Patel V; Lahusen T; Sy T; Sausville EA; Gutkind JS; Senderowicz AM
    Cancer Res; 2002 Mar; 62(5):1401-9. PubMed ID: 11888912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Time-dependent changes in factors involved in the apoptotic process in human ovarian cancer cells as a response to cisplatin.
    Kolfschoten GM; Hulscher TM; Schrier SM; van Houten VM; Pinedo HM; Boven E
    Gynecol Oncol; 2002 Mar; 84(3):404-12. PubMed ID: 11855878
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of cell-cycle mediators in ovarian cancer cells after transfection with p16(INK4a), p21(WAF1/Cip-1), and p53.
    Ramirez PT; Gershenson DM; Tortolero-Luna G; Ramondetta LM; Fightmaster D; Wharton JT; Wolf JK
    Gynecol Oncol; 2001 Dec; 83(3):543-8. PubMed ID: 11733969
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
    Hayward RL; Macpherson JS; Cummings J; Monia BP; Smyth JF; Jodrell DI
    Clin Cancer Res; 2003 Jul; 9(7):2856-65. PubMed ID: 12855666
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells.
    Dornetshuber R; Heffeter P; Kamyar MR; Peterbauer T; Berger W; Lemmens-Gruber R
    Chem Res Toxicol; 2007 Mar; 20(3):465-73. PubMed ID: 17326668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.
    Jiang XH; Wong BC; Lin MC; Zhu GH; Kung HF; Jiang SH; Yang D; Lam SK
    Oncogene; 2001 Nov; 20(55):8009-18. PubMed ID: 11753684
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.
    Giannakakou P; Robey R; Fojo T; Blagosklonny MV
    Oncogene; 2001 Jun; 20(29):3806-13. PubMed ID: 11439344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
    Hill R; Leidal AM; Madureira PA; Gillis LD; Cochrane HK; Waisman DM; Chiu A; Lee PW
    DNA Repair (Amst); 2008 Feb; 7(2):239-52. PubMed ID: 18024214
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The p53 stabilizing compound CP-31398 induces apoptosis by activating the intrinsic Bax/mitochondrial/caspase-9 pathway.
    Luu Y; Bush J; Cheung KJ; Li G
    Exp Cell Res; 2002 Jun; 276(2):214-22. PubMed ID: 12027451
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
    Zopf S; Neureiter D; Bouralexis S; Abt T; Glaser KB; Okamoto K; Ganslmayer M; Hahn EG; Herold C; Ocker M
    Int J Oncol; 2007 Dec; 31(6):1391-402. PubMed ID: 17982666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function.
    Kokontis JM; Wagner AJ; O'Leary M; Liao S; Hay N
    Oncogene; 2001 Feb; 20(6):659-68. PubMed ID: 11313999
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status.
    Al-Ayyoubi S; Gali-Muhtasib H
    Mol Carcinog; 2007 Mar; 46(3):176-86. PubMed ID: 17192871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells.
    Gupta S; Afaq F; Mukhtar H
    Oncogene; 2002 May; 21(23):3727-38. PubMed ID: 12032841
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TNF-alpha induced p21(WAF1) but not Bax in colon cancer cells WiDr with mutated p53: important role of protein stabilization.
    Kobayashi N; Takada Y; Hachiya M; Ando K; Nakajima N; Akashi M
    Cytokine; 2000 Dec; 12(12):1745-54. PubMed ID: 11097743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog.
    Mujoo K; Watanabe M; Khokhar AR; Siddik ZH
    Prostate; 2005 Jan; 62(1):91-100. PubMed ID: 15389812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential sensitivity of normal and malignant breast epithelial cells to genistein is partly mediated by p21(WAF1).
    Upadhyay S; Neburi M; Chinni SR; Alhasan S; Miller F; Sarkar FH
    Clin Cancer Res; 2001 Jun; 7(6):1782-9. PubMed ID: 11410520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV).
    Hagopian GS; Mills GB; Khokhar AR; Bast RC; Siddik ZH
    Clin Cancer Res; 1999 Mar; 5(3):655-63. PubMed ID: 10100719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tirapazamine cytotoxicity for neuroblastoma is p53 dependent.
    Yang B; Reynolds CP
    Clin Cancer Res; 2005 Apr; 11(7):2774-80. PubMed ID: 15814660
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 56.