These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 15726644)

  • 1. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.
    Saini SP; Mu Y; Gong H; Toma D; Uppal H; Ren S; Li S; Poloyac SM; Xie W
    Hepatology; 2005 Mar; 41(3):497-505. PubMed ID: 15726644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J; Huang W; Qatanani M; Evans RM; Moore DD
    J Biol Chem; 2004 Nov; 279(47):49517-22. PubMed ID: 15358766
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
    Guo GL; Lambert G; Negishi M; Ward JM; Brewer HB; Kliewer SA; Gonzalez FJ; Sinal CJ
    J Biol Chem; 2003 Nov; 278(46):45062-71. PubMed ID: 12923173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
    Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of drug transporter gene expression by nuclear receptors.
    Staudinger JL; Madan A; Carol KM; Parkinson A
    Drug Metab Dispos; 2003 May; 31(5):523-7. PubMed ID: 12695338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PXR, CAR and drug metabolism.
    Willson TM; Kliewer SA
    Nat Rev Drug Discov; 2002 Apr; 1(4):259-66. PubMed ID: 12120277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
    Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B
    Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.
    Wang H; LeCluyse EL
    Clin Pharmacokinet; 2003; 42(15):1331-57. PubMed ID: 14674787
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
    Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
    Beigneux AP; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
    Biochem Biophys Res Commun; 2002 Apr; 293(1):145-9. PubMed ID: 12054576
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.
    Ding X; Staudinger JL
    Biochem Pharmacol; 2005 Mar; 69(5):867-73. PubMed ID: 15710363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of alterations in CAR on bilirubin detoxification in mouse collagen-induced arthritis.
    Kawase A; Tsunokuni Y; Iwaki M
    Drug Metab Dispos; 2007 Feb; 35(2):256-61. PubMed ID: 17108061
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S; Piquette-Miller M
    J Pharmacol Exp Ther; 2005 Feb; 312(2):841-8. PubMed ID: 15456840
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of cyp3a gene transcription by the pregnane x receptor.
    Goodwin B; Redinbo MR; Kliewer SA
    Annu Rev Pharmacol Toxicol; 2002; 42():1-23. PubMed ID: 11807162
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
    Anakk S; Kalsotra A; Kikuta Y; Huang W; Zhang J; Staudinger JL; Moore DD; Strobel HW
    Pharmacogenomics J; 2004; 4(2):91-101. PubMed ID: 14770174
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
    Ding X; Staudinger JL
    J Pharmacol Exp Ther; 2005 Jul; 314(1):120-7. PubMed ID: 15833898
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX; Wei W; Sun MF; Wu CY; Wang JP; Wei LZ; Zhou CF
    Free Radic Biol Med; 2004 Jul; 37(1):10-22. PubMed ID: 15183191
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.
    Sugatani J; Nishitani S; Yamakawa K; Yoshinari K; Sueyoshi T; Negishi M; Miwa M
    Mol Pharmacol; 2005 Mar; 67(3):845-55. PubMed ID: 15557560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Humanized xenobiotic response in mice expressing nuclear receptor SXR.
    Xie W; Barwick JL; Downes M; Blumberg B; Simon CM; Nelson MC; Neuschwander-Tetri BA; Brunt EM; Guzelian PS; Evans RM
    Nature; 2000 Jul; 406(6794):435-9. PubMed ID: 10935643
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.