BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 15731592)

  • 21. In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans.
    Hirota N; Ito K; Iwatsubo T; Green CE; Tyson CA; Shimada N; Suzuki H; Sugiyama Y
    Biopharm Drug Dispos; 2001 Mar; 22(2):53-71. PubMed ID: 11745908
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5.
    Cook CS; Berry LM; Kim DH; Burton EG; Hribar JD; Zhang L
    Drug Metab Dispos; 2002 Dec; 30(12):1344-51. PubMed ID: 12433801
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5.
    Bakken GV; Rudberg I; Christensen H; Molden E; Refsum H; Hermann M
    Drug Metab Dispos; 2009 Feb; 37(2):254-8. PubMed ID: 19022943
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Metabolism of levo-alpha-Acetylmethadol (LAAM) by human liver cytochrome P450: involvement of CYP3A4 characterized by atypical kinetics with two binding sites.
    Oda Y; Kharasch ED
    J Pharmacol Exp Ther; 2001 Apr; 297(1):410-22. PubMed ID: 11259570
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.
    Westlind-Johnsson A; Malmebo S; Johansson A; Otter C; Andersson TB; Johansson I; Edwards RJ; Boobis AR; Ingelman-Sundberg M
    Drug Metab Dispos; 2003 Jun; 31(6):755-61. PubMed ID: 12756208
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Utility of recombinant enzyme kinetics in prediction of human clearance: impact of variability, CYP3A5, and CYP2C19 on CYP3A4 probe substrates.
    Galetin A; Brown C; Hallifax D; Ito K; Houston JB
    Drug Metab Dispos; 2004 Dec; 32(12):1411-20. PubMed ID: 15342470
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance.
    Yun CH; Wood M; Wood AJ; Guengerich FP
    Anesthesiology; 1992 Sep; 77(3):467-74. PubMed ID: 1519785
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Evidence of significant contribution from CYP3A5 to hepatic drug metabolism.
    Huang W; Lin YS; McConn DJ; Calamia JC; Totah RA; Isoherranen N; Glodowski M; Thummel KE
    Drug Metab Dispos; 2004 Dec; 32(12):1434-45. PubMed ID: 15383492
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
    Lee HK; Moon JK; Chang CH; Choi H; Park HW; Park BS; Lee HS; Hwang EC; Lee YD; Liu KH; Kim JH
    Drug Metab Dispos; 2006 Jul; 34(7):1090-5. PubMed ID: 16581944
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism.
    Lin YS; Dowling AL; Quigley SD; Farin FM; Zhang J; Lamba J; Schuetz EG; Thummel KE
    Mol Pharmacol; 2002 Jul; 62(1):162-72. PubMed ID: 12065767
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs.
    McConn DJ; Lin YS; Allen K; Kunze KL; Thummel KE
    Drug Metab Dispos; 2004 Oct; 32(10):1083-91. PubMed ID: 15377640
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genetic contribution to variable human CYP3A-mediated metabolism.
    Lamba JK; Lin YS; Schuetz EG; Thummel KE
    Adv Drug Deliv Rev; 2002 Nov; 54(10):1271-94. PubMed ID: 12406645
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine.
    Topletz AR; Dennison JB; Barbuch RJ; Hadden CE; Hall SD; Renbarger JL
    Drug Metab Dispos; 2013 Sep; 41(9):1651-61. PubMed ID: 23780963
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In vitro metabolism of cyclosporine A by human kidney CYP3A5.
    Dai Y; Iwanaga K; Lin YS; Hebert MF; Davis CL; Huang W; Kharasch ED; Thummel KE
    Biochem Pharmacol; 2004 Nov; 68(9):1889-902. PubMed ID: 15450954
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.
    Mouly SJ; Matheny C; Paine MF; Smith G; Lamba J; Lamba V; Pusek SN; Schuetz EG; Stewart PW; Watkins PB
    Clin Pharmacol Ther; 2005 Dec; 78(6):605-18. PubMed ID: 16338276
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation.
    McCune JS; Risler LJ; Phillips BR; Thummel KE; Blough D; Shen DD
    Drug Metab Dispos; 2005 Jul; 33(7):1074-81. PubMed ID: 15821045
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Possible involvement of multiple cytochrome P450S in fentanyl and sufentanil metabolism as opposed to alfentanil.
    Guitton J; Buronfosse T; Désage M; Lepape A; Brazier JL; Beaune P
    Biochem Pharmacol; 1997 Jun; 53(11):1613-9. PubMed ID: 9264313
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.
    Kharasch ED; Hoffer C; Whittington D; Sheffels P
    Clin Pharmacol Ther; 2004 Sep; 76(3):250-69. PubMed ID: 15371986
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Intraindividual variability in male hepatic CYP3A4 activity assessed by alfentanil and midazolam clearance.
    Kharasch ED; Jubert C; Senn T; Bowdle TA; Thummel KE
    J Clin Pharmacol; 1999 Jul; 39(7):664-9. PubMed ID: 10392320
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Limited contribution of CYP3A5 to the hepatic 6beta-hydroxylation of testosterone.
    Kamdem LK; Meineke I; Koch I; Zanger UM; Brockmöller J; Wojnowski L
    Naunyn Schmiedebergs Arch Pharmacol; 2004 Jul; 370(1):71-7. PubMed ID: 15232676
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.