BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

539 related articles for article (PubMed ID: 15738311)

  • 1. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.
    Gómez-Benito M; Marzo I; Anel A; Naval J
    Mol Pharmacol; 2005 Jun; 67(6):1991-8. PubMed ID: 15738311
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.
    Marzo I; Pérez-Galán P; Giraldo P; López-Royuela N; Gómez-Benito M; Larrad L; Lasierra P; Rubio-Félix D; Anel A; Naval J
    Leukemia; 2004 Oct; 18(10):1599-604. PubMed ID: 15356656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF; Jiang CC; Kiejda KA; Gillespie S; Zhang XD; Hersey P
    Clin Cancer Res; 2007 Aug; 13(16):4934-42. PubMed ID: 17652623
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria.
    Marzo I; Pérez-Galán P; Giraldo P; Rubio-Félix D; Anel A; Naval J
    Biochem J; 2001 Nov; 359(Pt 3):537-46. PubMed ID: 11672427
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P; Wuillème-Toumi S; Ménoret E; Trichet V; Robillard N; Philippe M; Bataille R; Amiot M
    Cancer Res; 2007 Jun; 67(11):5418-24. PubMed ID: 17545623
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.
    Panaretakis T; Pokrovskaja K; Shoshan MC; Grandér D
    Oncogene; 2003 Jul; 22(29):4543-56. PubMed ID: 12881711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia.
    Bellosillo B; Villamor N; López-Guillermo A; Marcé S; Bosch F; Campo E; Montserrat E; Colomer D
    Blood; 2002 Sep; 100(5):1810-6. PubMed ID: 12176904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin.
    Gómez-Benito M; Balsas P; Carvajal-Vergara X; Pandiella A; Anel A; Marzo I; Naval J
    Cell Signal; 2007 Apr; 19(4):844-54. PubMed ID: 17158029
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.
    Ramírez-Labrada A; López-Royuela N; Jarauta V; Galán-Malo P; Azaceta G; Palomera L; Pardo J; Anel A; Marzo I; Naval J
    Clin Transl Oncol; 2015 Feb; 17(2):121-32. PubMed ID: 25037851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S; Borrow J; Zhang XD; Hersey P
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells.
    Gomez-Bougie P; Bataille R; Amiot M
    Eur J Immunol; 2004 Nov; 34(11):3156-64. PubMed ID: 15459900
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
    Rosato RR; Almenara JA; Coe S; Grant S
    Cancer Res; 2007 Oct; 67(19):9490-500. PubMed ID: 17909059
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins.
    Callus BA; Moujallad DM; Silke J; Gerl R; Jabbour AM; Ekert PG; Vaux DL
    J Mol Biol; 2008 Dec; 384(2):313-23. PubMed ID: 18835564
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
    Lim DY; Park JH
    Am J Physiol Gastrointest Liver Physiol; 2009 May; 296(5):G1060-8. PubMed ID: 19264955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ; Ng LT; Lin CC
    Eur J Pharmacol; 2005 Aug; 518(2-3):96-106. PubMed ID: 16054126
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH; Lin R; Perez-Soler R
    Mol Pharmacol; 2008 Sep; 74(3):793-806. PubMed ID: 18524889
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LIGHT sensitizes IFNgamma-mediated apoptosis of MDA-MB-231 breast cancer cells leading to down-regulation of anti-apoptosis Bcl-2 family members.
    Zhang M; Guo R; Zhai Y; Yang D
    Cancer Lett; 2003 Jun; 195(2):201-10. PubMed ID: 12767529
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia.
    Pérez-Galán P; Marzo I; Giraldo P; Rubio-Félix D; Lasierra P; Larrad L; Anel A; Naval J
    Leukemia; 2002 Oct; 16(10):2106-14. PubMed ID: 12357364
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.
    Boya P; Gonzalez-Polo RA; Poncet D; Andreau K; Vieira HL; Roumier T; Perfettini JL; Kroemer G
    Oncogene; 2003 Jun; 22(25):3927-36. PubMed ID: 12813466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.