BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 15739896)

  • 1. Search for histamine H3 receptor antagonists with combined inhibitory potency at Ntau-methyltransferase: ether derivatives.
    Apelt J; Grassmann S; Ligneau X; Pertz HH; Ganellin CR; Arrang JM; Schwartz JC; Schunack W; Stark H
    Pharmazie; 2005 Feb; 60(2):97-106. PubMed ID: 15739896
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities.
    Grassmann S; Apelt J; Sippl W; Ligneau X; Pertz HH; Zhao YH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    Bioorg Med Chem; 2003 May; 11(10):2163-74. PubMed ID: 12713826
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity.
    Apelt J; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2002 Feb; 45(5):1128-41. PubMed ID: 11855993
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands.
    Yates SL; Phillips JG; Gregory R; Pawlowski GP; Fadnis L; Khan MA; Ali SM; Tedford CE
    J Pharmacol Exp Ther; 1999 May; 289(2):1151-9. PubMed ID: 10215699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives.
    Grassmann S; Apelt J; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    Arch Pharm (Weinheim); 2004 Oct; 337(10):533-45. PubMed ID: 15476285
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of FUB 181, a selective histamine H3-receptor antagonist of high oral in vivo potency with 4-(omega-(arylalkyloxy)alkyl)-1H-imidazole structure.
    Stark H; Hüls A; Ligneau X; Purand K; Pertz H; Arrang JM; Schwartz JC; Schunack W
    Arch Pharm (Weinheim); 1998 Jun; 331(6):211-8. PubMed ID: 9713254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Kovalainen JT; Christiaans JA; Kotisaari S; Laitinen JT; Männistö PT; Tuomisto L; Gynther J
    J Med Chem; 1999 Apr; 42(7):1193-202. PubMed ID: 10197963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.
    Gbahou F; Vincent L; Humbert-Claude M; Tardivel-Lacombe J; Chabret C; Arrang JM
    Br J Pharmacol; 2006 Apr; 147(7):744-54. PubMed ID: 16432504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists.
    Mikó T; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    Bioorg Med Chem; 2004 May; 12(10):2727-36. PubMed ID: 15110854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ether derivatives of 3-piperidinopropan-1-ol as non-imidazole histamine H3 receptor antagonists.
    Łazewska D; Ligneau X; Schwartz JC; Schunack W; Stark H; Kieć-Kononowicz K
    Bioorg Med Chem; 2006 May; 14(10):3522-9. PubMed ID: 16466921
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Search for novel leads for histamine H3-receptor antagonists: oxygen-containing derivatives.
    Stark H; Hüls A; Ligneau X; Arrang JM; Schwartz JC; Schunack W
    Pharmazie; 1997 Jul; 52(7):495-500. PubMed ID: 9266588
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Piperidine-containing histamine H3 receptor antagonists of the carbamate series: the influence of the additional ether functionality.
    Łazewska D; Kieć-Kononowicz K; Pertz HH; Elz S; Stark H; Schunack W
    Pharmazie; 2002 Dec; 57(12):791-5. PubMed ID: 12561236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.
    Meier G; Apelt J; Reichert U; Grassmann S; Ligneau X; Elz S; Leurquin F; Ganellin CR; Schwartz JC; Schunack W; Stark H
    Eur J Pharm Sci; 2001 Jun; 13(3):249-59. PubMed ID: 11384847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity.
    Krause M; Ligneau X; Stark H; Garbarg M; Schwartz JC; Schunack W
    J Med Chem; 1998 Oct; 41(21):4171-6. PubMed ID: 9767653
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors.
    Vacondio F; Mor M; Silva C; Zuliani V; Rivara M; Rivara S; Bordi F; Plazzi PV; Magnanini F; Bertoni S; Ballabeni V; Barocelli E; Carrupt PA; Testa B
    Eur J Pharm Sci; 2004 Sep; 23(1):89-98. PubMed ID: 15324926
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Piperidine-containing histamine H3-receptor antagonists of the carbamate series: variation of the spacer length.
    Łazewska D; Kieć-Kononowicz K; Pertz HH; Stark H; Schunack W; Elz S
    Pharmazie; 2001 Dec; 56(12):927-32. PubMed ID: 11802653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
    Mikó T; Ligneau X; Pertz HH; Ganellin CR; Arrang JM; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2003 Apr; 46(8):1523-30. PubMed ID: 12672253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Replacement of imidazole by a piperidine moiety differentially affects the potency of histamine H3-receptor antagonists.
    Liedtke S; Flau K; Kathmann M; Schlicker E; Stark H; Meier G; Schunack W
    Naunyn Schmiedebergs Arch Pharmacol; 2003 Jan; 367(1):43-50. PubMed ID: 12616340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
    Watanabe M; Kazuta Y; Hayashi H; Yamada S; Matsuda A; Shuto S
    J Med Chem; 2006 Sep; 49(18):5587-96. PubMed ID: 16942032
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ligands of the histamine H3-receptor: new potent antagonists of the 2-thioimidazole type.
    Plazzi PV; Mor M; Bordi F; Silva C; Rivara S; Caretta A; Ballabeni V; Impicciatore M; Vitali T
    Farmaco; 1997 May; 52(5):295-302. PubMed ID: 9274000
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.