These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 15741340)

  • 1. Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.
    Chrysina ED; Kosmopoulou MN; Tiraidis C; Kardakaris R; Bischler N; Leonidas DD; Hadady Z; Somsak L; Docsa T; Gergely P; Oikonomakos NG
    Protein Sci; 2005 Apr; 14(4):873-88. PubMed ID: 15741340
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
    Tsirkone VG; Tsoukala E; Lamprakis C; Manta S; Hayes JM; Skamnaki VT; Drakou C; Zographos SE; Komiotis D; Leonidas DD
    Bioorg Med Chem; 2010 May; 18(10):3413-25. PubMed ID: 20430629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A new allosteric site in glycogen phosphorylase b as a target for drug interactions.
    Oikonomakos NG; Skamnaki VT; Tsitsanou KE; Gavalas NG; Johnson LN
    Structure; 2000 Jun; 8(6):575-84. PubMed ID: 10873856
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM; Hayes JM; Tiraidis C; Zographos SE; Leonidas DD; Chrysina ED; Archontis G; Oikonomakos NG; Paul JV; Varghese B; Loganathan D
    Proteins; 2008 May; 71(3):1307-23. PubMed ID: 18041758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE; Hayes JM; Keramioti M; Mamais M; Oikonomakos NG; Kato A; Leonidas DD; Zographos SE
    Food Chem Toxicol; 2013 Nov; 61():14-27. PubMed ID: 23279842
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors.
    Alexacou KM; Tenchiu Deleanu AC; Chrysina ED; Charavgi MD; Kostas ID; Zographos SE; Oikonomakos NG; Leonidas DD
    Bioorg Med Chem; 2010 Nov; 18(22):7911-22. PubMed ID: 20947361
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
    Oikonomakos NG; Kosmopoulou M; Zographos SE; Leonidas DD; Chrysina ED; Somsák L; Nagy V; Praly JP; Docsa T; Tóth B; Gergely P
    Eur J Biochem; 2002 Mar; 269(6):1684-96. PubMed ID: 11895439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B.
    Oikonomakos NG; Skamnaki VT; Osz E; Szilágyi L; Somsák L; Docsa T; Tóth B; Gergely P
    Bioorg Med Chem; 2002 Feb; 10(2):261-8. PubMed ID: 11741774
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: kinetic and crystallographic studies.
    Pinotsis N; Leonidas DD; Chrysina ED; Oikonomakos NG; Mavridis IM
    Protein Sci; 2003 Sep; 12(9):1914-24. PubMed ID: 12930991
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
    Oikonomakos NG; Tsitsanou KE; Zographos SE; Skamnaki VT; Goldmann S; Bischoff H
    Protein Sci; 1999 Oct; 8(10):1930-45. PubMed ID: 10548038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies.
    Chrysina ED; Kosmopoulou MN; Kardakaris R; Bischler N; Leonidas DD; Kannan T; Loganathan D; Oikonomakos NG
    Bioorg Med Chem; 2005 Feb; 13(3):765-72. PubMed ID: 15653344
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Halogen-substituted (C-β-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase.
    Alexacou KM; Zhang YZ; Praly JP; Zographos SE; Chrysina ED; Oikonomakos NG; Leonidas DD
    Bioorg Med Chem; 2011 Sep; 19(17):5125-36. PubMed ID: 21821421
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
    Leonidas DD; Oikonomakos NG; Papageorgiou AC; Acharya KR; Barford D; Johnson LN
    Protein Sci; 1992 Sep; 1(9):1112-22. PubMed ID: 1304390
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.
    Zographos SE; Oikonomakos NG; Tsitsanou KE; Leonidas DD; Chrysina ED; Skamnaki VT; Bischoff H; Goldmann S; Watson KA; Johnson LN
    Structure; 1997 Nov; 5(11):1413-25. PubMed ID: 9384557
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of variously coupled conjugates of D-glucose, 1,3,4-oxadiazole, and 1,2,3-triazole for inhibition of glycogen phosphorylase.
    Kun S; Nagy GZ; Tóth M; Czecze L; Van Nhien AN; Docsa T; Gergely P; Charavgi MD; Skourti PV; Chrysina ED; Patonay T; Somsák L
    Carbohydr Res; 2011 Sep; 346(12):1427-38. PubMed ID: 21470596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
    Gregoriou M; Noble ME; Watson KA; Garman EF; Krulle TM; de la Fuente C; Fleet GW; Oikonomakos NG; Johnson LN
    Protein Sci; 1998 Apr; 7(4):915-27. PubMed ID: 9568898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.
    Kosmopoulou MN; Leonidas DD; Chrysina ED; Bischler N; Eisenbrand G; Sakarellos CE; Pauptit R; Oikonomakos NG
    Eur J Biochem; 2004 Jun; 271(11):2280-90. PubMed ID: 15153119
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
    Kun S; Begum J; Kyriakis E; Stamati ECV; Barkas TA; Szennyes E; Bokor É; Szabó KE; Stravodimos GA; Sipos Á; Docsa T; Gergely P; Moffatt C; Patraskaki MS; Kokolaki MC; Gkerdi A; Skamnaki VT; Leonidas DD; Somsák L; Hayes JM
    Eur J Med Chem; 2018 Mar; 147():266-278. PubMed ID: 29453094
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
    Barford D; Hu SH; Johnson LN
    J Mol Biol; 1991 Mar; 218(1):233-60. PubMed ID: 1900534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
    Kantsadi AL; Bokor É; Kun S; Stravodimos GA; Chatzileontiadou DSM; Leonidas DD; Juhász-Tóth É; Szakács A; Batta G; Docsa T; Gergely P; Somsák L
    Eur J Med Chem; 2016 Nov; 123():737-745. PubMed ID: 27522507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.