337 related articles for article (PubMed ID: 15743177)
1. Synthesis and biological evaluation of meperidine analogues at monoamine transporters.
Lomenzo SA; Rhoden JB; Izenwasser S; Wade D; Kopajtic T; Katz JL; Trudell ML
J Med Chem; 2005 Mar; 48(5):1336-43. PubMed ID: 15743177
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
[TBL] [Abstract][Full Text] [Related]
3. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.
Zhang S; Zhen J; Reith ME; Dutta AK
J Med Chem; 2005 Jul; 48(15):4962-71. PubMed ID: 16033275
[TBL] [Abstract][Full Text] [Related]
5. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
[TBL] [Abstract][Full Text] [Related]
6. Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.
Carroll FI; Runyon SP; Abraham P; Navarro H; Kuhar MJ; Pollard GT; Howard JL
J Med Chem; 2004 Dec; 47(25):6401-9. PubMed ID: 15566309
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
Carroll FI; Pawlush N; Kuhar MJ; Pollard GT; Howard JL
J Med Chem; 2004 Jan; 47(2):296-302. PubMed ID: 14711303
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and monoamine transporter binding of 2-(diarylmethoxymethyl)-3 beta-aryltropane derivatives.
Xu L; Kulkarni SS; Izenwasser S; Katz JL; Kopajtic T; Lomenzo SA; Newman AH; Trudell ML
J Med Chem; 2004 Mar; 47(7):1676-82. PubMed ID: 15027858
[TBL] [Abstract][Full Text] [Related]
9. Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
Cao J; Kulkarni SS; Husbands SM; Bowen WD; Williams W; Kopajtic T; Katz JL; George C; Newman AH
J Med Chem; 2003 Jun; 46(13):2589-98. PubMed ID: 12801223
[TBL] [Abstract][Full Text] [Related]
10. Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.
Huang Y; Bae SA; Zhu Z; Guo N; Roth BL; Laruelle M
J Med Chem; 2005 Apr; 48(7):2559-70. PubMed ID: 15801845
[TBL] [Abstract][Full Text] [Related]
11. Studies of the biogenic amine transporters. 10. Characterization of a novel cocaine binding site in brain membranes prepared from dopamine transporter knockout mice.
Rothman RB; Carroll FI; Morales M; Rowley DL; Rice KC; Dersch CM; Donovan DM
Synapse; 2002 May; 44(2):94-105. PubMed ID: 11891881
[TBL] [Abstract][Full Text] [Related]
12. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
Ghorai SK; Cook C; Davis M; Venkataraman SK; George C; Beardsley PM; Reith ME; Dutta AK
J Med Chem; 2003 Mar; 46(7):1220-8. PubMed ID: 12646032
[TBL] [Abstract][Full Text] [Related]
13. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
Kolhatkar R; Cook CD; Ghorai SK; Deschamps J; Beardsley PM; Reith ME; Dutta AK
J Med Chem; 2004 Oct; 47(21):5101-13. PubMed ID: 15456254
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds.
Carroll FI; Tyagi S; Blough BE; Kuhar MJ; Navarro HA
J Med Chem; 2005 Jun; 48(11):3852-7. PubMed ID: 15916437
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
Dutta AK; Fei XS; Beardsley PM; Newman JL; Reith ME
J Med Chem; 2001 Mar; 44(6):937-48. PubMed ID: 11300876
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.
Greiner E; Prisinzano T; Johnson EM; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
J Med Chem; 2003 Apr; 46(8):1465-9. PubMed ID: 12672246
[TBL] [Abstract][Full Text] [Related]
17. Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
Dutta AK; Xu C; Reith ME
J Med Chem; 1998 Aug; 41(17):3293-7. PubMed ID: 9703474
[TBL] [Abstract][Full Text] [Related]
18. Structure-activity studies of 3'-4'-dichloro-meperidine analogues at dopamine and serotonin transporters.
Rhoden JB; Bouvet M; Izenwasser S; Wade D; Lomenzo SA; Trudell ML
Bioorg Med Chem; 2005 Oct; 13(19):5623-34. PubMed ID: 15993612
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.
Lomenzo SA; Izenwasser S; Katz JL; Terry PD; Zhu N; Klein CL; Trudell ML
J Med Chem; 1997 Dec; 40(26):4406-14. PubMed ID: 9435910
[TBL] [Abstract][Full Text] [Related]
20. Potent and selective ligands for the dopamine transporter (DAT): structure-activity relationship studies of novel 4-[2-(diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine analogues.
Dutta AK; Coffey LL; Reith ME
J Med Chem; 1998 Feb; 41(5):699-705. PubMed ID: 9513598
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]