BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

544 related articles for article (PubMed ID: 15746193)

  • 1. Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells.
    Sharma D; Blum J; Yang X; Beaulieu N; Macleod AR; Davidson NE
    Mol Endocrinol; 2005 Jul; 19(7):1740-51. PubMed ID: 15746193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure.
    Ghoshal K; Datta J; Majumder S; Bai S; Dong X; Parthun M; Jacob ST
    Mol Cell Biol; 2002 Dec; 22(23):8302-19. PubMed ID: 12417732
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation.
    Zhou Q; Atadja P; Davidson NE
    Cancer Biol Ther; 2007 Jan; 6(1):64-9. PubMed ID: 17172825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.
    Yang X; Phillips DL; Ferguson AT; Nelson WG; Herman JG; Davidson NE
    Cancer Res; 2001 Oct; 61(19):7025-9. PubMed ID: 11585728
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation.
    El-Osta A; Kantharidis P; Zalcberg JR; Wolffe AP
    Mol Cell Biol; 2002 Mar; 22(6):1844-57. PubMed ID: 11865062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins.
    Majumder S; Kutay H; Datta J; Summers D; Jacob ST; Ghoshal K
    J Cell Biochem; 2006 Apr; 97(6):1300-16. PubMed ID: 16329111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells.
    Meng CF; Zhu XJ; Peng G; Dai DQ
    Oncol Rep; 2009 Nov; 22(5):1221-7. PubMed ID: 19787243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
    Woodfield GW; Hitchler MJ; Chen Y; Domann FE; Weigel RJ
    Clin Cancer Res; 2009 Jun; 15(11):3672-9. PubMed ID: 19458056
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation.
    Scott SA; Dong WF; Ichinohasama R; Hirsch C; Sheridan D; Sanche SE; Geyer CR; Decoteau JF
    Leuk Res; 2006 Jan; 30(1):69-76. PubMed ID: 16043219
    [TBL] [Abstract][Full Text] [Related]  

  • 10. pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-alpha in breast cancer.
    Macaluso M; Cinti C; Russo G; Russo A; Giordano A
    Oncogene; 2003 Jun; 22(23):3511-7. PubMed ID: 12789259
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.
    Magdinier F; Wolffe AP
    Proc Natl Acad Sci U S A; 2001 Apr; 98(9):4990-5. PubMed ID: 11309512
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes.
    Sharma D; Saxena NK; Davidson NE; Vertino PM
    Cancer Res; 2006 Jun; 66(12):6370-8. PubMed ID: 16778215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.
    Mossman D; Kim KT; Scott RJ
    BMC Cancer; 2010 Jul; 10():366. PubMed ID: 20618997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.
    Keen JC; Yan L; Mack KM; Pettit C; Smith D; Sharma D; Davidson NE
    Breast Cancer Res Treat; 2003 Oct; 81(3):177-86. PubMed ID: 14620913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription.
    Zhang Y; Fatima N; Dufau ML
    Mol Cell Biol; 2005 Sep; 25(18):7929-39. PubMed ID: 16135786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
    Konduri SD; Srivenugopal KS; Yanamandra N; Dinh DH; Olivero WC; Gujrati M; Foster DC; Kisiel W; Ali-Osman F; Kondraganti S; Lakka SS; Rao JS
    Oncogene; 2003 Jul; 22(29):4509-16. PubMed ID: 12881707
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications.
    Meeran SM; Patel SN; Li Y; Shukla S; Tollefsbol TO
    PLoS One; 2012; 7(5):e37748. PubMed ID: 22662208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine.
    David GL; Yegnasubramanian S; Kumar A; Marchi VL; De Marzo AM; Lin X; Nelson WG
    Cancer Biol Ther; 2004 Jun; 3(6):540-8. PubMed ID: 15034303
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines.
    Meng CF; Zhu XJ; Peng G; Dai DQ
    World J Gastroenterol; 2007 Dec; 13(46):6166-71. PubMed ID: 18069755
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts.
    Gozzini A; Santini V
    Ann Hematol; 2005 Dec; 84 Suppl 1():54-60. PubMed ID: 16228241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.