These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

393 related articles for article (PubMed ID: 15749826)

  • 1. X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO.
    Morizane Y; Honda R; Fukami K; Yasuda H
    J Biochem; 2005 Feb; 137(2):125-32. PubMed ID: 15749826
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.
    MacFarlane M; Merrison W; Bratton SB; Cohen GM
    J Biol Chem; 2002 Sep; 277(39):36611-6. PubMed ID: 12121969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
    Fu J; Jin Y; Arend LJ
    J Biol Chem; 2003 Dec; 278(52):52660-72. PubMed ID: 14523016
    [TBL] [Abstract][Full Text] [Related]  

  • 4. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP; Bonavida B
    Mol Cancer Ther; 2002 Oct; 1(12):1051-8. PubMed ID: 12481428
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
    Vucic D; Franklin MC; Wallweber HJ; Das K; Eckelman BP; Shin H; Elliott LO; Kadkhodayan S; Deshayes K; Salvesen GS; Fairbrother WJ
    Biochem J; 2005 Jan; 385(Pt 1):11-20. PubMed ID: 15485396
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins.
    Creagh EM; Murphy BM; Duriez PJ; Duckett CS; Martin SJ
    J Biol Chem; 2004 Jun; 279(26):26906-14. PubMed ID: 15078891
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
    Srinivasula SM; Hegde R; Saleh A; Datta P; Shiozaki E; Chai J; Lee RA; Robbins PD; Fernandes-Alnemri T; Shi Y; Alnemri ES
    Nature; 2001 Mar; 410(6824):112-6. PubMed ID: 11242052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
    Saito A; Hayashi T; Okuno S; Ferrand-Drake M; Chan PH
    J Cereb Blood Flow Metab; 2003 Sep; 23(9):1010-9. PubMed ID: 12973017
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD; Zhang XY; Gray CP; Nguyen T; Hersey P
    Cancer Res; 2001 Oct; 61(19):7339-48. PubMed ID: 11585775
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo.
    Gao Z; Tian Y; Wang J; Yin Q; Wu H; Li YM; Jiang X
    J Biol Chem; 2007 Oct; 282(42):30718-27. PubMed ID: 17724022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites.
    Silke J; Hawkins CJ; Ekert PG; Chew J; Day CL; Pakusch M; Verhagen AM; Vaux DL
    J Cell Biol; 2002 Apr; 157(1):115-24. PubMed ID: 11927604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.
    Yang QH; Du C
    J Biol Chem; 2004 Apr; 279(17):16963-70. PubMed ID: 14960576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition.
    Wilkinson JC; Wilkinson AS; Scott FL; Csomos RA; Salvesen GS; Duckett CS
    J Biol Chem; 2004 Dec; 279(49):51082-90. PubMed ID: 15371416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis.
    Silke J; Kratina T; Ekert PG; Pakusch M; Vaux DL
    J Biol Chem; 2004 Feb; 279(6):4313-21. PubMed ID: 14570909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A; Brady NR
    J Biol Chem; 2015 Sep; 290(36):22005-18. PubMed ID: 26134559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO.
    Hu S; Yang X
    J Biol Chem; 2003 Mar; 278(12):10055-60. PubMed ID: 12525502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.
    Suzuki Y; Nakabayashi Y; Takahashi R
    Proc Natl Acad Sci U S A; 2001 Jul; 98(15):8662-7. PubMed ID: 11447297
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
    Srinivasula SM; Datta P; Fan XJ; Fernandes-Alnemri T; Huang Z; Alnemri ES
    J Biol Chem; 2000 Nov; 275(46):36152-7. PubMed ID: 10950947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ.
    Arnt CR; Chiorean MV; Heldebrant MP; Gores GJ; Kaufmann SH
    J Biol Chem; 2002 Nov; 277(46):44236-43. PubMed ID: 12218061
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels.
    Kominsky DJ; Bickel RJ; Tyler KL
    J Virol; 2002 Nov; 76(22):11414-24. PubMed ID: 12388702
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.