These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 15750116)

  • 1. Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation.
    Weber J; Chakraborty B; Weberova J; Miller MD; Quiñones-Mateu ME
    J Clin Microbiol; 2005 Mar; 43(3):1395-400. PubMed ID: 15750116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity.
    White KL; Margot NA; Wrin T; Petropoulos CJ; Miller MD; Naeger LK
    Antimicrob Agents Chemother; 2002 Nov; 46(11):3437-46. PubMed ID: 12384348
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus.
    Chunduri H; Rimland D; Nurpeisov V; Crumpacker CS; Sharma PL
    Virol J; 2011 Jan; 8():33. PubMed ID: 21255423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains.
    Li S; Ouyang J; Zhao B; An M; Wang L; Ding H; Zhang M; Han X
    BMC Infect Dis; 2020 Feb; 20(1):123. PubMed ID: 32046664
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions.
    Deval J; Navarro JM; Selmi B; Courcambeck J; Boretto J; Halfon P; Garrido-Urbani S; Sire J; Canard B
    J Biol Chem; 2004 Jun; 279(24):25489-96. PubMed ID: 15044478
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation.
    García-Lerma JG; MacInnes H; Bennett D; Reid P; Nidtha S; Weinstock H; Kaplan JE; Heneine W
    J Virol; 2003 May; 77(10):5685-93. PubMed ID: 12719561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduced viral fitness and lack of cross-class resistance with integrase strand transfer inhibitor and nucleoside reverse transcriptase inhibitor resistance mutations.
    Andreatta KN; Goodman DD; Miller MD; White KL
    Antimicrob Agents Chemother; 2015; 59(6):3441-9. PubMed ID: 25824231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Drug Susceptibility and Viral Fitness of HIV-1 with Integrase Strand Transfer Inhibitor Resistance Substitution Q148R or N155H in Combination with Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Resistance Substitutions.
    Andreatta KN; Miller MD; White KL
    Antimicrob Agents Chemother; 2016 Feb; 60(2):757-65. PubMed ID: 26574015
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prevalence, genotypic associations and phenotypic characterization of K65R, L74V and other HIV-1 RT resistance mutations in a commercial database.
    McColl DJ; Chappey C; Parkin NT; Miller MD
    Antivir Ther; 2008; 13(2):189-97. PubMed ID: 18505170
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation.
    Svarovskaia ES; Feng JY; Margot NA; Myrick F; Goodman D; Ly JK; White KL; Kutty N; Wang R; Borroto-Esoda K; Miller MD
    J Acquir Immune Defic Syndr; 2008 Aug; 48(4):428-36. PubMed ID: 18614922
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.
    Van Rompay KK; Johnson JA; Blackwood EJ; Singh RP; Lipscomb J; Matthews TB; Marthas ML; Pedersen NC; Bischofberger N; Heneine W; North TW
    Retrovirology; 2007 Apr; 4():25. PubMed ID: 17417971
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine.
    García-Lerma JG; MacInnes H; Bennett D; Weinstock H; Heneine W
    J Virol; 2004 Jul; 78(14):7545-52. PubMed ID: 15220429
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect on HIV-1 viral replication capacity of DTG-resistance mutations in NRTI/NNRTI resistant viruses.
    Pham HT; Mesplède T; Wainberg MA
    Retrovirology; 2016 Apr; 13(1):31. PubMed ID: 27130466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors.
    Fourati S; Visseaux B; Armenia D; Morand-Joubert L; Artese A; Charpentier C; Van Den Eede P; Costa G; Alcaro S; Wirden M; Perno CF; Ceccherini Silberstein F; Descamps D; Calvez V; Marcelin AG
    J Antimicrob Chemother; 2013 Oct; 68(10):2199-204. PubMed ID: 23749955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
    Sluis-Cremer N; Sheen CW; Zelina S; Torres PS; Parikh UM; Mellors JW
    Antimicrob Agents Chemother; 2007 Jan; 51(1):48-53. PubMed ID: 17088490
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.
    Pingen M; Wensing AM; Fransen K; De Bel A; de Jong D; Hoepelman AI; Magiorkinis E; Paraskevis D; Lunar MM; Poljak M; Nijhuis M; Boucher CA;
    Retrovirology; 2014 Nov; 11():105. PubMed ID: 25575025
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine.
    Feng JY; Myrick FT; Margot NA; Mulamba GB; Rimsky L; Borroto-Esoda K; Selmi B; Canard B
    Nucleosides Nucleotides Nucleic Acids; 2006; 25(1):89-107. PubMed ID: 16440988
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Individual contributions of mutant protease and reverse transcriptase to viral infectivity, replication, and protein maturation of antiretroviral drug-resistant human immunodeficiency virus type 1.
    Bleiber G; Munoz M; Ciuffi A; Meylan P; Telenti A
    J Virol; 2001 Apr; 75(7):3291-300. PubMed ID: 11238855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of the Q207D mutation in HIV type 1 reverse transcriptase on zidovudine susceptibility and replicative fitness.
    Lu J; Whitcomb J; Kuritzkes DR
    J Acquir Immune Defic Syndr; 2005 Sep; 40(1):20-3. PubMed ID: 16123676
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques.
    Ambrose Z; Boltz V; Palmer S; Coffin JM; Hughes SH; Kewalramani VN
    J Virol; 2004 Dec; 78(24):13553-61. PubMed ID: 15564466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.