180 related articles for article (PubMed ID: 15750181)
1. Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids.
Yu C; Wang F; Jin C; Huang X; McKeehan WL
J Biol Chem; 2005 May; 280(18):17707-14. PubMed ID: 15750181
[TBL] [Abstract][Full Text] [Related]
2. Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4.
Yu C; Wang F; Kan M; Jin C; Jones RB; Weinstein M; Deng CX; McKeehan WL
J Biol Chem; 2000 May; 275(20):15482-9. PubMed ID: 10809780
[TBL] [Abstract][Full Text] [Related]
3. Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.
Gupta S; Stravitz RT; Dent P; Hylemon PB
J Biol Chem; 2001 May; 276(19):15816-22. PubMed ID: 11278771
[TBL] [Abstract][Full Text] [Related]
4. Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity.
Wang C; Yang C; Chang JY; You P; Li Y; Jin C; Luo Y; Li X; McKeehan WL; Wang F
Curr Mol Med; 2014; 14(6):703-711. PubMed ID: 25056539
[TBL] [Abstract][Full Text] [Related]
5. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
Gupta S; Natarajan R; Payne SG; Studer EJ; Spiegel S; Dent P; Hylemon PB
J Biol Chem; 2004 Feb; 279(7):5821-8. PubMed ID: 14660582
[TBL] [Abstract][Full Text] [Related]
6. Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.
Song KH; Li T; Owsley E; Strom S; Chiang JY
Hepatology; 2009 Jan; 49(1):297-305. PubMed ID: 19085950
[TBL] [Abstract][Full Text] [Related]
7. Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway.
Kouno T; Liu X; Zhao H; Kisseleva T; Cable EE; Schnabl B
J Biol Chem; 2022 Jul; 298(7):102056. PubMed ID: 35605662
[TBL] [Abstract][Full Text] [Related]
8. Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes.
Song KH; Ellis E; Strom S; Chiang JY
Hepatology; 2007 Dec; 46(6):1993-2002. PubMed ID: 17924446
[TBL] [Abstract][Full Text] [Related]
9. Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.
Holt JA; Luo G; Billin AN; Bisi J; McNeill YY; Kozarsky KF; Donahee M; Wang DY; Mansfield TA; Kliewer SA; Goodwin B; Jones SA
Genes Dev; 2003 Jul; 17(13):1581-91. PubMed ID: 12815072
[TBL] [Abstract][Full Text] [Related]
10. FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway.
Jung D; York JP; Wang L; Yang C; Zhang A; Francis HL; Webb P; McKeehan WL; Alpini G; Lesage GD; Moore DD; Xia X
Pflugers Arch; 2014 May; 466(5):1011-9. PubMed ID: 24068255
[TBL] [Abstract][Full Text] [Related]
11. Fibroblast Growth Factor 21 Response in a Preclinical Alcohol Model of Acute-on-Chronic Liver Injury.
Christidis G; Karatayli E; Hall RA; Weber SN; Reichert MC; Hohl M; Qiao S; Boehm U; Lütjohann D; Lammert F; Karatayli SC
Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360670
[TBL] [Abstract][Full Text] [Related]
12. Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice.
Yu C; Wang F; Jin C; Wu X; Chan WK; McKeehan WL
Am J Pathol; 2002 Dec; 161(6):2003-10. PubMed ID: 12466116
[TBL] [Abstract][Full Text] [Related]
13. A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver.
Rodríguez-Ortigosa CM; Celay J; Olivas I; Juanarena N; Arcelus S; Uriarte I; Marín JJ; Avila MA; Medina JF; Prieto J
Gastroenterology; 2014 Nov; 147(5):1084-93. PubMed ID: 25066374
[TBL] [Abstract][Full Text] [Related]
14. FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.
Shin DJ; Osborne TF
J Biol Chem; 2009 Apr; 284(17):11110-20. PubMed ID: 19237543
[TBL] [Abstract][Full Text] [Related]
15. Fibroblast growth factor 7 inhibits cholesterol 7α-hydroxylase gene expression in hepatocytes.
Sun Z; Yu X; Wu W; Jia D; Chen Y; Ji L; Liu X; Peng X; Li Y; Yang L; Ruan Y; Gu J; Ren S; Zhang S
Biochem Biophys Res Commun; 2012 Jul; 423(4):775-80. PubMed ID: 22713451
[TBL] [Abstract][Full Text] [Related]
16. Mechanisms for increased expression of cholesterol 7alpha-hydroxylase (Cyp7a1) in lactating rats.
Wooton-Kee CR; Coy DJ; Athippozhy AT; Zhao T; Jones BR; Vore M
Hepatology; 2010 Jan; 51(1):277-85. PubMed ID: 19957370
[TBL] [Abstract][Full Text] [Related]
17. Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis.
Huang X; Yang C; Jin C; Luo Y; Wang F; McKeehan WL
Mol Carcinog; 2009 Jun; 48(6):553-62. PubMed ID: 19009564
[TBL] [Abstract][Full Text] [Related]
18. Disrupted Murine Gut-to-Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models.
Chow EC; Quach HP; Zhang Y; Wang JZ; Evans DC; Li AP; Silva J; Tirona RG; Lai Y; Pang KS
J Pharmacol Exp Ther; 2017 Jan; 360(1):174-191. PubMed ID: 27789682
[TBL] [Abstract][Full Text] [Related]
19. The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.
De Fabiani E; Mitro N; Anzulovich AC; Pinelli A; Galli G; Crestani M
J Biol Chem; 2001 Aug; 276(33):30708-16. PubMed ID: 11402042
[TBL] [Abstract][Full Text] [Related]
20. Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.
Lee YK; Schmidt DR; Cummins CL; Choi M; Peng L; Zhang Y; Goodwin B; Hammer RE; Mangelsdorf DJ; Kliewer SA
Mol Endocrinol; 2008 Jun; 22(6):1345-56. PubMed ID: 18323469
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
