107 related articles for article (PubMed ID: 15753995)
1. Inhibition of choline kinase renders a highly selective cytotoxic effect in tumour cells through a mitochondrial independent mechanism.
Rodríguez-González A; Ramírez de Molina A; Bañez-Coronel M; Megias D; Lacal JC
Int J Oncol; 2005 Apr; 26(4):999-1008. PubMed ID: 15753995
[TBL] [Abstract][Full Text] [Related]
2. Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of action.
Rodríguez-González A; Ramirez de Molina A; Fernández F; Lacal JC
Oncogene; 2004 Oct; 23(50):8247-59. PubMed ID: 15378008
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.
Rodríguez-González A; Ramírez de Molina A; Fernández F; Ramos MA; del Carmen Núñez M; Campos J; Lacal JC
Oncogene; 2003 Dec; 22(55):8803-12. PubMed ID: 14654777
[TBL] [Abstract][Full Text] [Related]
4. Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
Al-Saffar NM; Troy H; Ramírez de Molina A; Jackson LE; Madhu B; Griffiths JR; Leach MO; Workman P; Lacal JC; Judson IR; Chung YL
Cancer Res; 2006 Jan; 66(1):427-34. PubMed ID: 16397258
[TBL] [Abstract][Full Text] [Related]
5. Choline kinase inhibitors as a novel approach for antiproliferative drug design.
Hernández-Alcoceba R; Saniger L; Campos J; Núñez MC; Khaless F; Gallo MA; Espinosa A; Lacal JC
Oncogene; 1997 Nov; 15(19):2289-301. PubMed ID: 9393874
[TBL] [Abstract][Full Text] [Related]
6. A novel 4,4'-bispyridyl-5,5'-perfluoroalkyl-2,2'-bisoxazol with antitumoral activity via cell cycle arrest and induction of apoptosis.
Báñez-Coronel M; Rodríguez-González A; Martín-Cantalejo Y; Sáez B; Soto J; Villa MJ; Braña MF; Lacal JC
Int J Oncol; 2004 Oct; 25(4):1097-103. PubMed ID: 15375561
[TBL] [Abstract][Full Text] [Related]
7. Suppression of human ovarian SKOV-3 cancer cell growth by Duchesnea phenolic fraction is associated with cell cycle arrest and apoptosis.
Peng B; Chang Q; Wang L; Hu Q; Wang Y; Tang J; Liu X
Gynecol Oncol; 2008 Jan; 108(1):173-81. PubMed ID: 17959232
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells.
Ahn MY; Lee J; Na YJ; Choi WS; Lee BM; Kang KW; Kim HS
Chem Biol Interact; 2009 May; 179(2-3):169-77. PubMed ID: 19070610
[TBL] [Abstract][Full Text] [Related]
9. Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.
Ramírez de Molina A; Báñez-Coronel M; Gutiérrez R; Rodríguez-González A; Olmeda D; Megías D; Lacal JC
Cancer Res; 2004 Sep; 64(18):6732-9. PubMed ID: 15374991
[TBL] [Abstract][Full Text] [Related]
10. Loss of mitochondrial membrane potential and caspase activation enhance apoptosis in irradiated K562 cells treated with herbimycin A.
Jo WS; Jeong MH; Jin YH; Jang JY; Nam BH; Son SH; Choi SS; Yoo YH; Kang CD; Lee JD; Jeong SJ
Int J Radiat Biol; 2005 Jul; 81(7):531-43. PubMed ID: 16263657
[TBL] [Abstract][Full Text] [Related]
11. Isokotomolide A, a new butanolide extracted from the leaves of Cinnamomum kotoense, arrests cell cycle progression and induces apoptosis through the induction of p53/p21 and the initiation of mitochondrial system in human non-small cell lung cancer A549 cells.
Chen CY; Hsu YL; Chen YY; Hung JY; Huang MS; Kuo PL
Eur J Pharmacol; 2007 Nov; 574(2-3):94-102. PubMed ID: 17707793
[TBL] [Abstract][Full Text] [Related]
12. Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells.
Tong WG; Ding XZ; Talamonti MS; Bell RH; Adrian TE
Anticancer Drugs; 2007 Jun; 18(5):535-41. PubMed ID: 17414622
[TBL] [Abstract][Full Text] [Related]
13. A novel histone deacetylase inhibitor, Scriptaid, induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells.
Takai N; Ueda T; Nishida M; Nasu K; Narahara H
Int J Mol Med; 2006 Feb; 17(2):323-9. PubMed ID: 16391833
[TBL] [Abstract][Full Text] [Related]
14. Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy.
Ramírez de Molina A; Gallego-Ortega D; Sarmentero-Estrada J; Lagares D; Gómez Del Pulgar T; Bandrés E; García-Foncillas J; Lacal JC
Int J Biochem Cell Biol; 2008; 40(9):1753-63. PubMed ID: 18296102
[TBL] [Abstract][Full Text] [Related]
15. Loss of cardiolipin in palmitate-treated GL15 glioblastoma cells favors cytochrome c release from mitochondria leading to apoptosis.
Buratta M; Castigli E; Sciaccaluga M; Pellegrino RM; Spinozzi F; Roberti R; Corazzi L
J Neurochem; 2008 May; 105(3):1019-31. PubMed ID: 18182042
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of ChoK is an efficient antitumor strategy for Harvey-, Kirsten-, and N-ras-transformed cells.
Ramírez de Molina A; Rodríguez-González A; Penalva V; Lucas L; Lacal JC
Biochem Biophys Res Commun; 2001 Jul; 285(4):873-9. PubMed ID: 11467831
[TBL] [Abstract][Full Text] [Related]
17. Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK.
Park C; Jin CY; Kim GY; Choi IW; Kwon TK; Choi BT; Lee SJ; Lee WH; Choi YH
Toxicol Appl Pharmacol; 2008 Mar; 227(2):219-28. PubMed ID: 18031783
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of K+ efflux prevents mitochondrial dysfunction, and suppresses caspase-3-, apoptosis-inducing factor-, and endonuclease G-mediated constitutive apoptosis in human neutrophils.
El Kebir D; József L; Khreiss T; Filep JG
Cell Signal; 2006 Dec; 18(12):2302-13. PubMed ID: 16806822
[TBL] [Abstract][Full Text] [Related]
19. (2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells.
Reyes FJ; Centelles JJ; Lupiáñez JA; Cascante M
FEBS Lett; 2006 Nov; 580(27):6302-10. PubMed ID: 17083937
[TBL] [Abstract][Full Text] [Related]
20. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
Hsu YL; Cho CY; Kuo PL; Huang YT; Lin CC
J Pharmacol Exp Ther; 2006 Aug; 318(2):484-94. PubMed ID: 16632641
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
