146 related articles for article (PubMed ID: 15755664)
1. Enzymatic hydrolysis of stampidine and other stavudine phosphoramidates in the presence of mammalian proteases.
Venkatachalam TK; Samuel P; Uckun FM
Bioorg Med Chem; 2005 Apr; 13(7):2651-5. PubMed ID: 15755664
[TBL] [Abstract][Full Text] [Related]
2. Lipase-mediated stereoselective hydrolysis of stampidine and other phosphoramidate derivatives of stavudine.
Venkatachalam TK; Samuel P; Li G; Qazi S; Mao C; Pendergrass S; Uckun FM
Bioorg Med Chem; 2004 Jun; 12(12):3371-81. PubMed ID: 15158806
[TBL] [Abstract][Full Text] [Related]
3. Protease-mediated enzymatic hydrolysis and activation of aryl phosphoramidate derivatives of stavudine.
Venkatachalam TK; Samuel P; Qazi S; Uckun FM
Eur J Med Chem; 2005 May; 40(5):452-66. PubMed ID: 15893019
[TBL] [Abstract][Full Text] [Related]
4. Stereochemical influence on lipase-mediated hydrolysis and biological activity of stampidine and other stavudine phosphoramidates.
Venkatachalam TK; Samuel P; Uckun FM
Bioorg Med Chem; 2005 Mar; 13(5):1763-73. PubMed ID: 15698793
[TBL] [Abstract][Full Text] [Related]
5. Effect of change in nucleoside structure on the activation and antiviral activity of phosphoramidate derivatives.
Venkatachalam TK; Samuel P; Qazi S; Uckun FM
Bioorg Med Chem; 2005 Sep; 13(18):5408-23. PubMed ID: 15994083
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and metabolism of naphthyl substituted phosphoramidate derivatives of stavudine.
Venkatachalam TK; Qazi S; Uckun FM
Bioorg Med Chem; 2006 Aug; 14(15):5161-77. PubMed ID: 16697204
[TBL] [Abstract][Full Text] [Related]
7. A comparative study of the hydrolysis pathways of substituted aryl phosphoramidate versus aryl thiophosphoramidate derivatives of stavudine.
Venkatachalam TK; Yu G; Samuel P; Qazi S; Pendergrass S; Uckun FM
Eur J Med Chem; 2004 Aug; 39(8):665-83. PubMed ID: 15276300
[TBL] [Abstract][Full Text] [Related]
8. Site-specific enzymatic activation of the anti-HIV agent stampidine.
Venkatachalam TK; Qazi S; Uckun FM
Arzneimittelforschung; 2006 Feb; 56(2A):167-75. PubMed ID: 16570825
[TBL] [Abstract][Full Text] [Related]
9. Development and evaluation of a thermoreversible ovule formulation of stampidine, a novel nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.
D'Cruz OJ; Samuel P; Waurzyniak B; Uckun FM
Biol Reprod; 2003 Dec; 69(6):1843-51. PubMed ID: 12890726
[TBL] [Abstract][Full Text] [Related]
10. Effect of alkyl groups on the cellular hydrolysis of stavudine phosphoramidates.
Venkatachalam TK; Sarquis M; Qazi S; Uckun FM
Bioorg Med Chem; 2006 Sep; 14(18):6420-33. PubMed ID: 16782353
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of stavudine-5'-[p-bromophenyl methoxyalaninyl phosphate], stampidine, in mice, dogs, and cats.
Chen CL; Yu G; Venkatachalam TK; Uckun FM
Drug Metab Dispos; 2002 Dec; 30(12):1523-31. PubMed ID: 12433828
[TBL] [Abstract][Full Text] [Related]
12. Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.
D'Cruz OJ; Uckun FM
Fertil Steril; 2004 Mar; 81 Suppl 1():831-41. PubMed ID: 15019817
[TBL] [Abstract][Full Text] [Related]
13. Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.
Uckun FM; Pendergrass S; Qazi S; Samuel P; Venkatachalam TK
Eur J Med Chem; 2004 Mar; 39(3):225-34. PubMed ID: 15051170
[TBL] [Abstract][Full Text] [Related]
14. Stampidine: a selective oculo-genital microbicide.
D'Cruz OJ; Uckun FM
J Antimicrob Chemother; 2005 Jul; 56(1):10-9. PubMed ID: 15919769
[TBL] [Abstract][Full Text] [Related]
15. Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study.
Uckun FM; DuMez D; Qazi S; Tibbles H; Venkatachalam TK
Arzneimittelforschung; 2007; 57(2):112-21. PubMed ID: 17396622
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, separation and anti-HIV activity of distereoisomers of N-[p-(4-bromophenyl) -2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester (stampidine).
Venkatachalam TK; Qazi S; Uckun FM
Arzneimittelforschung; 2006 Feb; 56(2A):152-8. PubMed ID: 16570823
[TBL] [Abstract][Full Text] [Related]
17. Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro.
Siccardi D; Gumbleton M; Omidi Y; McGuigan C
Eur J Pharm Sci; 2004 May; 22(1):25-31. PubMed ID: 15113580
[TBL] [Abstract][Full Text] [Related]
18. Unmet challenges in HIV therapy and potential of stampidine.
Uckun FM
Arzneimittelforschung; 2006 Feb; 56(2A):117-20. PubMed ID: 16570820
[No Abstract] [Full Text] [Related]
19. Large-scale synthesis and formulation of GMP-grade stampidine, a new anti-HIV agent.
DuMez D; Venkatachalam TK; Uckun FM
Arzneimittelforschung; 2006 Feb; 56(2A):136-51. PubMed ID: 16570822
[TBL] [Abstract][Full Text] [Related]
20. Toxicity and pharmacokinetics of stampidine in mice and rats.
Uckun FM; Chen CL; Lisowski E; Mitcheltree GC; Venkatachalam TK; Erbeck D; Chen H; Waurzyniak B
Arzneimittelforschung; 2003; 53(5):357-67. PubMed ID: 12854363
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]