BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

485 related articles for article (PubMed ID: 15769469)

  • 21. Functional mapping of conserved, surface-exposed charges of antibody variable domains.
    Weidenhaupt M; Khalifa MB; Hugo N; Choulier L; Altschuh D; Vernet T
    J Mol Recognit; 2002; 15(2):94-103. PubMed ID: 11954054
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.
    Saerens D; Conrath K; Govaert J; Muyldermans S
    J Mol Biol; 2008 Mar; 377(2):478-88. PubMed ID: 18262543
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effects on interaction kinetics of mutations at the VH-VL interface of Fabs depend on the structural context.
    Khalifa MB; Weidenhaupt M; Choulier L; Chatellier J; Rauffer-Bruyère N; Altschuh D; Vernet T
    J Mol Recognit; 2000; 13(3):127-39. PubMed ID: 10867708
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Role of the domain-domain interaction in the construction of the antigen combining site. A comparative study by 1H-15N shift correlation NMR spectroscopy of the Fv and Fab fragments of anti-dansyl mouse monoclonal antibody.
    Takahashi H; Tamura H; Shimba N; Shimada I; Arata Y
    J Mol Biol; 1994 Oct; 243(3):494-503. PubMed ID: 7966275
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterization of a quaternary-structured folding intermediate of an antibody Fab-fragment.
    Lilie H; Jaenicke R; Buchner J
    Protein Sci; 1995 May; 4(5):917-24. PubMed ID: 7663347
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Folding and oxidation of the antibody domain C(H)3.
    Thies MJ; Talamo F; Mayer M; Bell S; Ruoppolo M; Marino G; Buchner J
    J Mol Biol; 2002 Jun; 319(5):1267-77. PubMed ID: 12079363
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Improving the productivity of single-chain Fv antibody against c-Met by rearranging the order of its variable domains.
    Kim YJ; Neelamegam R; Heo MA; Edwardraja S; Paik HJ; Lee SG
    J Microbiol Biotechnol; 2008 Jun; 18(6):1186-90. PubMed ID: 18600066
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Folding and assembly of an antibody Fv fragment, a heterodimer stabilized by antigen.
    Jäger M; Plückthun A
    J Mol Biol; 1999 Feb; 285(5):2005-19. PubMed ID: 9925781
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Optimizing recombinant antibody function in SPR immunosensing. The influence of antibody structural format and chip surface chemistry on assay sensitivity.
    Townsend S; Finlay WJ; Hearty S; O'Kennedy R
    Biosens Bioelectron; 2006 Aug; 22(2):268-74. PubMed ID: 16487701
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Towards a universal disulphide stabilised single chain Fv format: importance of interchain disulphide bond location and vL-vH orientation.
    Weatherill EE; Cain KL; Heywood SP; Compson JE; Heads JT; Adams R; Humphreys DP
    Protein Eng Des Sel; 2012 Jul; 25(7):321-9. PubMed ID: 22586154
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: neutralization capacity versus thermodynamic stability.
    Quintero-Hernández V; Del Pozo-Yauner L; Pedraza-Escalona M; Juárez-González VR; Alcántara-Recillas I; Possani LD; Becerril B
    Immunol Lett; 2012 Apr; 143(2):152-60. PubMed ID: 22306104
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation.
    Ramm K; Gehrig P; Plückthun A
    J Mol Biol; 1999 Jul; 290(2):535-46. PubMed ID: 10390351
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Folding nuclei of the scFv fragment of an antibody.
    Freund C; Honegger A; Hunziker P; Holak TA; Plückthun A
    Biochemistry; 1996 Jun; 35(25):8457-64. PubMed ID: 8679604
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Heat-induced structural changes in the Fab fragment of IgG recognized by molecular dynamics stimulation--implications for signal transduction in antibodies.
    Roterman I; Konieczny L; Stopa B; Rybarska J; Piekarska B
    Folia Biol (Krakow); 1994; 42(3-4):115-28. PubMed ID: 7641940
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework.
    Kügler M; Stein C; Schwenkert M; Saul D; Vockentanz L; Huber T; Wetzel SK; Scholz O; Plückthun A; Honegger A; Fey GH
    Protein Eng Des Sel; 2009 Mar; 22(3):135-47. PubMed ID: 19188138
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Factors influencing the dimer to monomer transition of an antibody single-chain Fv fragment.
    Arndt KM; Müller KM; Plückthun A
    Biochemistry; 1998 Sep; 37(37):12918-26. PubMed ID: 9737871
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Direct evidence by H/D exchange and ESI-MS for transient unproductive domain interaction in the refolding of an antibody scFv fragment.
    Jäger M; Plückthun A
    Protein Sci; 2000 Mar; 9(3):552-63. PubMed ID: 10752617
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression.
    Demarest SJ; Chen G; Kimmel BE; Gustafson D; Wu J; Salbato J; Poland J; Elia M; Tan X; Wong K; Short J; Hansen G
    Protein Eng Des Sel; 2006 Jul; 19(7):325-36. PubMed ID: 16672248
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [New type recombinant antibody fragment scFv multimer and cancer targeting].
    Guo J; Cai M
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2003 Jun; 20(2):361-5. PubMed ID: 12856620
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The location of an engineered inter-subunit disulfide bond in factor for inversion stimulation (FIS) affects the denaturation pathway and cooperativity.
    Meinhold D; Beach M; Shao Y; Osuna R; Colón W
    Biochemistry; 2006 Aug; 45(32):9767-77. PubMed ID: 16893178
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 25.