BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 15769904)

  • 1. Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.
    Karlsson G; Liu Y; Larsson J; Goumans MJ; Lee JS; Thorgeirsson SS; Ringnér M; Karlsson S
    Physiol Genomics; 2005 May; 21(3):396-403. PubMed ID: 15769904
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function.
    Schniewind B; Groth S; Sebens Müerköster S; Sipos B; Schäfer H; Kalthoff H; Fändrich F; Ungefroren H
    Oncogene; 2007 Jul; 26(33):4850-62. PubMed ID: 17297450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
    Finnson KW; Parker WL; ten Dijke P; Thorikay M; Philip A
    J Bone Miner Res; 2008 Jun; 23(6):896-906. PubMed ID: 18333754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells.
    Ota T; Fujii M; Sugizaki T; Ishii M; Miyazawa K; Aburatani H; Miyazono K
    J Cell Physiol; 2002 Dec; 193(3):299-318. PubMed ID: 12384983
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors.
    Wu X; Ma J; Han JD; Wang N; Chen YG
    Microvasc Res; 2006 Jan; 71(1):12-9. PubMed ID: 16405919
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Downregulation of hepatocyte nuclear factor-4alpha and its role in regulation of gene expression by TGF-beta in mammary epithelial cells.
    Ishikawa F; Nose K; Shibanuma M
    Exp Cell Res; 2008 Jun; 314(10):2131-40. PubMed ID: 18433744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells.
    Lu S; Dong Z
    Prostate; 2006 Jun; 66(9):996-1004. PubMed ID: 16541418
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells.
    Safina A; Vandette E; Bakin AV
    Oncogene; 2007 Apr; 26(17):2407-22. PubMed ID: 17072348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling.
    König HG; Kögel D; Rami A; Prehn JH
    J Cell Biol; 2005 Mar; 168(7):1077-86. PubMed ID: 15781474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential responsiveness to autocrine and exogenous transforming growth factor (TGF) beta1 in cells with nonfunctional TGF-beta receptor type III.
    Deng X; Bellis S; Yan Z; Friedman E
    Cell Growth Differ; 1999 Jan; 10(1):11-8. PubMed ID: 9950213
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors.
    Goumans MJ; Valdimarsdottir G; Itoh S; Rosendahl A; Sideras P; ten Dijke P
    EMBO J; 2002 Apr; 21(7):1743-53. PubMed ID: 11927558
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ALK5 and Smad4 are involved in TGF-beta1-induced pulmonary endothelial permeability.
    Birukova AA; Adyshev D; Gorshkov B; Birukov KG; Verin AD
    FEBS Lett; 2005 Jul; 579(18):4031-7. PubMed ID: 16004987
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes.
    Bassing CH; Shou W; Muir S; Heitman J; Matzuk MM; Wang XF
    Cell Growth Differ; 1998 Mar; 9(3):223-8. PubMed ID: 9543388
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transforming growth factor-beta receptor requirements for the induction of the endothelin-1 gene.
    Castañares C; Redondo-Horcajo M; Magan-Marchal N; Lamas S; Rodriguez-Pascual F
    Exp Biol Med (Maywood); 2006 Jun; 231(6):700-3. PubMed ID: 16740983
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.
    Matsuyama S; Iwadate M; Kondo M; Saitoh M; Hanyu A; Shimizu K; Aburatani H; Mishima HK; Imamura T; Miyazono K; Miyazawa K
    Cancer Res; 2003 Nov; 63(22):7791-8. PubMed ID: 14633705
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.
    Yoo YA; Kang MH; Kim JS; Oh SC
    Carcinogenesis; 2008 Mar; 29(3):480-90. PubMed ID: 18174246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fibroblasts from chronic wounds show altered TGF-beta-signaling and decreased TGF-beta Type II receptor expression.
    Kim BC; Kim HT; Park SH; Cha JS; Yufit T; Kim SJ; Falanga V
    J Cell Physiol; 2003 Jun; 195(3):331-6. PubMed ID: 12704642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Signaling by ALK5 mediates TGF-beta-induced ET-1 expression in endothelial cells: a role for migration and proliferation.
    Castañares C; Redondo-Horcajo M; Magán-Marchal N; ten Dijke P; Lamas S; Rodríguez-Pascual F
    J Cell Sci; 2007 Apr; 120(Pt 7):1256-66. PubMed ID: 17376964
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7.
    DaCosta Byfield S; Major C; Laping NJ; Roberts AB
    Mol Pharmacol; 2004 Mar; 65(3):744-52. PubMed ID: 14978253
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
    Blaney Davidson EN; Remst DF; Vitters EL; van Beuningen HM; Blom AB; Goumans MJ; van den Berg WB; van der Kraan PM
    J Immunol; 2009 Jun; 182(12):7937-45. PubMed ID: 19494318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.