These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 15771236)

  • 1. Prediction of human drug clearance from in vitro and preclinical data using physiologically based and empirical approaches.
    Ito K; Houston JB
    Pharm Res; 2005 Jan; 22(1):103-12. PubMed ID: 15771236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.
    Fagerholm U
    J Pharm Pharmacol; 2007 Jun; 59(6):803-28. PubMed ID: 17637173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prediction of human pharmacokinetics--improving microsome-based predictions of hepatic metabolic clearance.
    Fagerholm U
    J Pharm Pharmacol; 2007 Oct; 59(10):1427-31. PubMed ID: 17910819
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes.
    Riley RJ; McGinnity DF; Austin RP
    Drug Metab Dispos; 2005 Sep; 33(9):1304-11. PubMed ID: 15932954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the use of liver models for predicting drug clearance using in vitro kinetic data from hepatic microsomes and isolated hepatocytes.
    Ito K; Houston JB
    Pharm Res; 2004 May; 21(5):785-92. PubMed ID: 15180335
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.
    Naritomi Y; Terashita S; Kimura S; Suzuki A; Kagayama A; Sugiyama Y
    Drug Metab Dispos; 2001 Oct; 29(10):1316-24. PubMed ID: 11560875
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance.
    Ring BJ; Chien JY; Adkison KK; Jones HM; Rowland M; Jones RD; Yates JW; Ku MS; Gibson CR; He H; Vuppugalla R; Marathe P; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
    J Pharm Sci; 2011 Oct; 100(10):4090-110. PubMed ID: 21541938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. On the prediction of hepatic clearance using the diluted plasma in metabolic stability assay.
    Berezhkovskiy LM; Khojasteh SC; Halladay JS; Hop CE
    J Pharm Sci; 2009 Jun; 98(6):1922-7. PubMed ID: 18837013
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance.
    Soars MG; Burchell B; Riley RJ
    J Pharmacol Exp Ther; 2002 Apr; 301(1):382-90. PubMed ID: 11907196
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substrate depletion approach for determining in vitro metabolic clearance: time dependencies in hepatocyte and microsomal incubations.
    Jones HM; Houston JB
    Drug Metab Dispos; 2004 Sep; 32(9):973-82. PubMed ID: 15319339
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance.
    Huang L; Berry L; Ganga S; Janosky B; Chen A; Roberts J; Colletti AE; Lin MH
    Drug Metab Dispos; 2010 Feb; 38(2):223-31. PubMed ID: 19875499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of human drug clearance by multiple metabolic pathways: integration of hepatic and intestinal microsomal and cytosolic data.
    Cubitt HE; Houston JB; Galetin A
    Drug Metab Dispos; 2011 May; 39(5):864-73. PubMed ID: 21303923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry.
    Sinha VK; Vaarties K; De Buck SS; Fenu LA; Nijsen M; Gilissen RA; Sanderson W; Van Uytsel K; Hoeben E; Van Peer A; Mackie CE; Smit JW
    Clin Pharmacokinet; 2011 May; 50(5):307-18. PubMed ID: 21456631
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation of intrinsic in vitro and in vivo clearance for drugs metabolized by hepatic UDP-glucuronosyltransferases in rats.
    Nakamori F; Naritomi Y; Furutani M; Takamura F; Miura H; Murai H; Terashita S; Teramura T
    Drug Metab Pharmacokinet; 2011; 26(5):465-73. PubMed ID: 21727754
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Verapamil hepatic clearance in four preclinical rat models: towards activity-based scaling.
    Nicolaï J; De Bruyn T; Van Veldhoven PP; Keemink J; Augustijns P; Annaert P
    Biopharm Drug Dispos; 2015 Oct; 36(7):462-80. PubMed ID: 25963583
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatic Organic Anion Transporting Polypeptide-Mediated Clearance in the Beagle Dog: Assessing In Vitro-In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance.
    Matsunaga N; Ufuk A; Morse BL; Bedwell DW; Bao J; Mohutsky MA; Hillgren KM; Hall SD; Houston JB; Galetin A
    Drug Metab Dispos; 2019 Mar; 47(3):215-226. PubMed ID: 30593544
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Application of hybrid approach based on empirical and physiological concept for predicting pharmacokinetics in humans--usefulness of exponent on prospective evaluation of predictability.
    Sayama H; Komura H; Kogayu M
    Drug Metab Dispos; 2013 Feb; 41(2):498-507. PubMed ID: 23209193
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds.
    Sohlenius-Sternbeck AK; Afzelius L; Prusis P; Neelissen J; Hoogstraate J; Johansson J; Floby E; Bengtsson A; Gissberg O; Sternbeck J; Petersson C
    Xenobiotica; 2010 Sep; 40(9):637-49. PubMed ID: 20624033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A global examination of allometric scaling for predicting human drug clearance and the prediction of large vertical allometry.
    Tang H; Mayersohn M
    J Pharm Sci; 2006 Aug; 95(8):1783-99. PubMed ID: 16795013
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Utility of hepatocytes in predicting drug metabolism: comparison of hepatic intrinsic clearance in rats and humans in vivo and in vitro.
    Naritomi Y; Terashita S; Kagayama A; Sugiyama Y
    Drug Metab Dispos; 2003 May; 31(5):580-8. PubMed ID: 12695346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.