330 related articles for article (PubMed ID: 15772082)
1. Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps.
Krauser JA; Guengerich FP
J Biol Chem; 2005 May; 280(20):19496-506. PubMed ID: 15772082
[TBL] [Abstract][Full Text] [Related]
2. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
Kim KH; Isin EM; Yun CH; Kim DH; Guengerich FP
FEBS J; 2006 May; 273(10):2223-31. PubMed ID: 16649998
[TBL] [Abstract][Full Text] [Related]
3. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
Yamazaki H; Johnson WW; Ueng YF; Shimada T; Guengerich FP
J Biol Chem; 1996 Nov; 271(44):27438-44. PubMed ID: 8910324
[TBL] [Abstract][Full Text] [Related]
4. Quantum tunneling in testosterone 6beta-hydroxylation by cytochrome P450: reaction dynamics calculations employing multiconfiguration molecular-mechanical potential energy surfaces.
Zhang Y; Lin H
J Phys Chem A; 2009 Oct; 113(43):11501-8. PubMed ID: 19480428
[TBL] [Abstract][Full Text] [Related]
5. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
Yamazaki H; Shimada T
Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
[TBL] [Abstract][Full Text] [Related]
6. Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11.
Kim D; Cha GS; Nagy LD; Yun CH; Guengerich FP
Biochemistry; 2014 Oct; 53(39):6161-72. PubMed ID: 25203493
[TBL] [Abstract][Full Text] [Related]
7. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.
Shaw PM; Hosea NA; Thompson DV; Lenius JM; Guengerich FP
Arch Biochem Biophys; 1997 Dec; 348(1):107-15. PubMed ID: 9390180
[TBL] [Abstract][Full Text] [Related]
8. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
Yamazaki H; Nakano M; Imai Y; Ueng YF; Guengerich FP; Shimada T
Arch Biochem Biophys; 1996 Jan; 325(2):174-82. PubMed ID: 8561495
[TBL] [Abstract][Full Text] [Related]
9. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
Shet MS; Faulkner KM; Holmans PL; Fisher CW; Estabrook RW
Arch Biochem Biophys; 1995 Apr; 318(2):314-21. PubMed ID: 7733659
[TBL] [Abstract][Full Text] [Related]
10. Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5.
Niwa T; Narita K; Okamoto A; Murayama N; Yamazaki H
J Pharm Pharm Sci; 2019; 22(1):332-339. PubMed ID: 31339834
[TBL] [Abstract][Full Text] [Related]
11. Development and validation of a high-throughput radiometric CYP3A4/5 inhibition assay using tritiated testosterone.
Di Marco A; Marcucci I; Verdirame M; Pérez J; Sanchez M; Peláez F; Chaudhary A; Laufer R
Drug Metab Dispos; 2005 Mar; 33(3):349-58. PubMed ID: 15608130
[TBL] [Abstract][Full Text] [Related]
12. Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis.
Wang RW; Newton DJ; Scheri TD; Lu AY
Drug Metab Dispos; 1997 Apr; 25(4):502-7. PubMed ID: 9107550
[TBL] [Abstract][Full Text] [Related]
13. Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.
Yamazaki H; Ueng YF; Shimada T; Guengerich FP
Biochemistry; 1995 Jul; 34(26):8380-9. PubMed ID: 7599128
[TBL] [Abstract][Full Text] [Related]
14. Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants.
Yun CH; Miller GP; Guengerich FP
Biochemistry; 2000 Sep; 39(37):11319-29. PubMed ID: 10985777
[TBL] [Abstract][Full Text] [Related]
15. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
Yamazaki H; Gillam EM; Dong MS; Johnson WW; Guengerich FP; Shimada T
Arch Biochem Biophys; 1997 Jun; 342(2):329-37. PubMed ID: 9186495
[TBL] [Abstract][Full Text] [Related]
16. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.
Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y
Arch Biochem Biophys; 2000 Sep; 381(1):164-70. PubMed ID: 11019832
[TBL] [Abstract][Full Text] [Related]
17. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
[TBL] [Abstract][Full Text] [Related]
18. Rate-limiting steps in oxidations catalyzed by rabbit cytochrome P450 1A2.
Guengerich FP; Krauser JA; Johnson WW
Biochemistry; 2004 Aug; 43(33):10775-88. PubMed ID: 15311939
[TBL] [Abstract][Full Text] [Related]
19. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe.
Wang H; Dick R; Yin H; Licad-Coles E; Kroetz DL; Szklarz G; Harlow G; Halpert JR; Correia MA
Biochemistry; 1998 Sep; 37(36):12536-45. PubMed ID: 9730826
[TBL] [Abstract][Full Text] [Related]
20. Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
Yamazaki H; Shimada T
Drug Metab Dispos; 1998 Nov; 26(11):1053-7. PubMed ID: 9806945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]