244 related articles for article (PubMed ID: 15777868)
1. New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids.
Pathirathna S; Brimelow BC; Jagodic MM; Krishnan K; Jiang X; Zorumski CF; Mennerick S; Covey DF; Todorovic SM; Jevtovic-Todorovic V
Pain; 2005 Apr; 114(3):429-443. PubMed ID: 15777868
[TBL] [Abstract][Full Text] [Related]
2. Enantioselective blockade of T-type Ca2+ current in adult rat sensory neurons by a steroid that lacks gamma-aminobutyric acid-modulatory activity.
Todorovic SM; Prakriya M; Nakashima YM; Nilsson KR; Han M; Zorumski CF; Covey DF; Lingle CJ
Mol Pharmacol; 1998 Nov; 54(5):918-27. PubMed ID: 9804627
[TBL] [Abstract][Full Text] [Related]
3. 5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain.
Pathirathna S; Todorovic SM; Covey DF; Jevtovic-Todorovic V
Pain; 2005 Oct; 117(3):326-339. PubMed ID: 16150542
[TBL] [Abstract][Full Text] [Related]
4. 5beta-reduced neuroactive steroids are novel voltage-dependent blockers of T-type Ca2+ channels in rat sensory neurons in vitro and potent peripheral analgesics in vivo.
Todorovic SM; Pathirathna S; Brimelow BC; Jagodic MM; Ko SH; Jiang X; Nilsson KR; Zorumski CF; Covey DF; Jevtovic-Todorovic V
Mol Pharmacol; 2004 Nov; 66(5):1223-35. PubMed ID: 15280444
[TBL] [Abstract][Full Text] [Related]
5. Modulation of GABA(A) receptor function by neuroactive steroids: evidence for heterogeneity of steroid sensitivity of recombinant GABA(A) receptor isoforms.
Maitra R; Reynolds JN
Can J Physiol Pharmacol; 1998 Sep; 76(9):909-20. PubMed ID: 10066142
[TBL] [Abstract][Full Text] [Related]
6. Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABA
Tesic V; Joksimovic SM; Quillinan N; Krishnan K; Covey DF; Todorovic SM; Jevtovic-Todorovic V
Br J Anaesth; 2020 May; 124(5):603-613. PubMed ID: 32151384
[TBL] [Abstract][Full Text] [Related]
7. Alphaxalone activates a Cl- conductance independent of GABAA receptors in cultured embryonic human dorsal root ganglion neurons.
Valeyev AY; Hackman JC; Holohean AM; Wood PM; Katz JL; Davidoff RA
J Neurophysiol; 1999 Jul; 82(1):10-5. PubMed ID: 10400930
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of multiple voltage-gated calcium channels may contribute to spinally mediated analgesia by epipregnanolone in a rat model of surgical paw incision.
Joksimovic SL; Donald RR; Park JY; Todorovic SM
Channels (Austin); 2019 Dec; 13(1):48-61. PubMed ID: 30672394
[TBL] [Abstract][Full Text] [Related]
9. Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels.
Tat QL; Joksimovic SM; Krishnan K; Covey DF; Todorovic SM; Jevtovic-Todorovic V
Cells; 2020 Dec; 9(12):. PubMed ID: 33322727
[TBL] [Abstract][Full Text] [Related]
10. GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids.
Mitchell EA; Gentet LJ; Dempster J; Belelli D
J Physiol; 2007 Sep; 583(Pt 3):1021-40. PubMed ID: 17656439
[TBL] [Abstract][Full Text] [Related]
11. Antagonism of neurosteroid modulation of native gamma-aminobutyric acid receptors by (3alpha,5alpha)-17-phenylandrost-16-en-3-ol.
Kelley SP; Alan JK; O'Buckley TK; Mennerick S; Krishnan K; Covey DF; Leslie Morrow A
Eur J Pharmacol; 2007 Oct; 572(2-3):94-101. PubMed ID: 17658511
[TBL] [Abstract][Full Text] [Related]
12. Antinociceptive effects of the neuroactive steroid, 3alpha-hydroxy-5alpha-pregnan-20-one and progesterone in the land snail, Cepaea nemoralis.
Kavaliers M; Perrot-Sinal TS; Desjardins DC; Cross-Mellor SK; Wiebe JP
Neuroscience; 2000; 95(3):807-12. PubMed ID: 10670448
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone.
Ayoola C; Hwang SM; Hong SJ; Rose KE; Boyd C; Bozic N; Park JY; Osuru HP; DiGruccio MR; Covey DF; Jevtovic-Todorovic V; Todorovic SM
Psychopharmacology (Berl); 2014 Sep; 231(17):3503-3515. PubMed ID: 24800894
[TBL] [Abstract][Full Text] [Related]
14. Redox modulation of T-type calcium channels in rat peripheral nociceptors.
Todorovic SM; Jevtovic-Todorovic V; Meyenburg A; Mennerick S; Perez-Reyes E; Romano C; Olney JW; Zorumski CF
Neuron; 2001 Jul; 31(1):75-85. PubMed ID: 11498052
[TBL] [Abstract][Full Text] [Related]
15. The anesthetic steroid (+)-3alpha-hydroxy-5alpha-androstane-17beta-carbonitrile blocks N-, Q-, and R-type, but not L- and P-type, high voltage-activated Ca2+ current in hippocampal and dorsal root ganglion neurons of the rat.
Nakashima YM; Todorovic SM; Covey DF; Lingle CJ
Mol Pharmacol; 1998 Sep; 54(3):559-68. PubMed ID: 9730915
[TBL] [Abstract][Full Text] [Related]
16. Multiple effects of allopregnanolone on GABAergic responses in single hippocampal CA3 pyramidal neurons.
Park HM; Choi IS; Nakamura M; Cho JH; Lee MG; Jang IS
Eur J Pharmacol; 2011 Feb; 652(1-3):46-54. PubMed ID: 21118679
[TBL] [Abstract][Full Text] [Related]
17. Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Zeng CM; Manion BD; Benz A; Evers AS; Zorumski CF; Mennerick S; Covey DF
J Med Chem; 2005 Apr; 48(8):3051-9. PubMed ID: 15828844
[TBL] [Abstract][Full Text] [Related]
18. Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
Hawkinson JE; Acosta-Burruel M; Yang KC; Hogenkamp DJ; Chen JS; Lan NC; Drewe JA; Whittemore ER; Woodward RM; Carter RB; Upasani RB
J Pharmacol Exp Ther; 1998 Oct; 287(1):198-207. PubMed ID: 9765338
[TBL] [Abstract][Full Text] [Related]
19. The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors.
Weir CJ; Ling AT; Belelli D; Wildsmith JA; Peters JA; Lambert JJ
Br J Anaesth; 2004 May; 92(5):704-11. PubMed ID: 15033889
[TBL] [Abstract][Full Text] [Related]
20. Differential modulation of the gamma-aminobutyric acid type C receptor by neuroactive steroids.
Morris KD; Moorefield CN; Amin J
Mol Pharmacol; 1999 Oct; 56(4):752-9. PubMed ID: 10496958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
