244 related articles for article (PubMed ID: 15777868)
21. Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats.
Hirani K; Sharma AN; Jain NS; Ugale RR; Chopde CT
Psychopharmacology (Berl); 2005 Jul; 180(2):267-78. PubMed ID: 15719223
[TBL] [Abstract][Full Text] [Related]
22. Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid.
Manzella FM; Cabrera OH; Wilkey D; Fine-Raquet B; Klawitter J; Krishnan K; Covey DF; Jevtovic-Todorovic V; Todorovic SM
Br J Anaesth; 2023 Feb; 130(2):154-164. PubMed ID: 36428160
[TBL] [Abstract][Full Text] [Related]
23. Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.
Rahman M; Lindblad C; Johansson IM; Bäckström T; Wang MD
Eur J Pharmacol; 2006 Oct; 547(1-3):37-44. PubMed ID: 16934248
[TBL] [Abstract][Full Text] [Related]
24. A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors.
Evers AS; Chen ZW; Manion BD; Han M; Jiang X; Darbandi-Tonkabon R; Kable T; Bracamontes J; Zorumski CF; Mennerick S; Steinbach JH; Covey DF
J Pharmacol Exp Ther; 2010 May; 333(2):404-13. PubMed ID: 20124410
[TBL] [Abstract][Full Text] [Related]
25. Enantioselective modulation of GABAergic synaptic transmission by steroids and benz[e]indenes in hippocampal microcultures.
Zorumski CF; Mennerick SJ; Covey DF
Synapse; 1998 Jun; 29(2):162-71. PubMed ID: 9593106
[TBL] [Abstract][Full Text] [Related]
26. Neuroactive steroids have multiple actions to potentiate GABAA receptors.
Akk G; Bracamontes JR; Covey DF; Evers A; Dao T; Steinbach JH
J Physiol; 2004 Jul; 558(Pt 1):59-74. PubMed ID: 15146041
[TBL] [Abstract][Full Text] [Related]
27. The role of T-type calcium channels in peripheral and central pain processing.
Todorovic SM; Jevtovic-Todorovic V
CNS Neurol Disord Drug Targets; 2006 Dec; 5(6):639-53. PubMed ID: 17168748
[TBL] [Abstract][Full Text] [Related]
28. Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia.
Covey DF; Nathan D; Kalkbrenner M; Nilsson KR; Hu Y; Zorumski CF; Evers AS
J Pharmacol Exp Ther; 2000 Jun; 293(3):1009-16. PubMed ID: 10869405
[TBL] [Abstract][Full Text] [Related]
29. Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues.
Bandyopadhyaya AK; Manion BD; Benz A; Taylor A; Rath NP; Evers AS; Zorumski CF; Mennerick S; Covey DF
Bioorg Med Chem Lett; 2010 Nov; 20(22):6680-4. PubMed ID: 20875742
[TBL] [Abstract][Full Text] [Related]
30. Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of δ(16)-alphaxalone and identification of a δ(17(20)) analogue with potent anesthetic activity.
Stastna E; Krishnan K; Manion BD; Taylor A; Rath NP; Chen ZW; Evers AS; Zorumski CF; Mennerick S; Covey DF
J Med Chem; 2011 Jun; 54(11):3926-34. PubMed ID: 21504158
[TBL] [Abstract][Full Text] [Related]
31. The anaesthetic action and modulation of GABAA receptor activity by the novel water-soluble aminosteroid Org 20599.
Hill-Venning C; Peters JA; Callachan H; Lambert JJ; Gemmell DK; Anderson A; Byford A; Hamilton N; Hill DR; Marshall RJ; Campbell AC
Neuropharmacology; 1996; 35(9-10):1209-22. PubMed ID: 9014136
[TBL] [Abstract][Full Text] [Related]
32. Blockade of Ba2+ current through human alpha1E channels by two steroid analogs, (+)-ACN and (+)-ECN.
Nakashima YM; Pereverzev A; Schneider T; Covey DF; Lingle CJ
Neuropharmacology; 1999 Jun; 38(6):843-55. PubMed ID: 10465688
[TBL] [Abstract][Full Text] [Related]
33. Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones.
Sooksawate T; Simmonds MA
Neuropharmacology; 1998 Sep; 37(9):1103-10. PubMed ID: 9833640
[TBL] [Abstract][Full Text] [Related]
34. Antinociceptive properties of neurosteroids II. Experiments with Saffan and its components alphaxalone and alphadolone to reveal separation of anaesthetic and antinociceptive effects and the involvement of spinal cord GABA(A) receptors.
Nadeson R; Goodchild CS
Pain; 2000 Oct; 88(1):31-39. PubMed ID: 11098097
[TBL] [Abstract][Full Text] [Related]
35. Selective T-type calcium channel blockade alleviates hyperalgesia in ob/ob mice.
Latham JR; Pathirathna S; Jagodic MM; Choe WJ; Levin ME; Nelson MT; Lee WY; Krishnan K; Covey DF; Todorovic SM; Jevtovic-Todorovic V
Diabetes; 2009 Nov; 58(11):2656-65. PubMed ID: 19651818
[TBL] [Abstract][Full Text] [Related]
36. Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Jiang X; Manion BD; Benz A; Rath NP; Evers AS; Zorumski CF; Mennerick S; Covey DF
J Med Chem; 2003 Dec; 46(25):5334-48. PubMed ID: 14640542
[TBL] [Abstract][Full Text] [Related]
37. Mechanisms of modulation of pregnanolone on glycinergic response in cultured spinal dorsal horn neurons of rat.
Jiang P; Yang CX; Wang YT; Xu TL
Neuroscience; 2006 Sep; 141(4):2041-50. PubMed ID: 16806717
[TBL] [Abstract][Full Text] [Related]
38. Neurosteroid modulation of allopregnanolone and GABA effect on the GABA-A receptor.
Strömberg J; Haage D; Taube M; Bäckström T; Lundgren P
Neuroscience; 2006 Nov; 143(1):73-81. PubMed ID: 16938407
[TBL] [Abstract][Full Text] [Related]
39. Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: a potential component of nociception.
Patte-Mensah C; Kibaly C; Mensah-Nyagan AG
Proc Natl Acad Sci U S A; 2005 Jun; 102(25):9044-9. PubMed ID: 15951421
[TBL] [Abstract][Full Text] [Related]
40. 17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities.
Runyon SP; Orr M; Navarro HA; Kepler JA; Rogawski MA; Kaminski RM; Cook CE
Eur J Pharmacol; 2009 Sep; 617(1-3):68-73. PubMed ID: 19577558
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
