These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

743 related articles for article (PubMed ID: 15780941)

  • 1. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme.
    Avalos JL; Bever KM; Wolberger C
    Mol Cell; 2005 Mar; 17(6):855-68. PubMed ID: 15780941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry.
    Sauve AA; Schramm VL
    Biochemistry; 2003 Aug; 42(31):9249-56. PubMed ID: 12899610
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.
    Borra MT; Langer MR; Slama JT; Denu JM
    Biochemistry; 2004 Aug; 43(30):9877-87. PubMed ID: 15274642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
    Zhao K; Harshaw R; Chai X; Marmorstein R
    Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8563-8. PubMed ID: 15150415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of NAD(+) in the deacetylase activity of the SIR2-like proteins.
    Landry J; Slama JT; Sternglanz R
    Biochem Biophys Res Commun; 2000 Nov; 278(3):685-90. PubMed ID: 11095969
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition.
    Sauve AA; Moir RD; Schramm VL; Willis IM
    Mol Cell; 2005 Feb; 17(4):595-601. PubMed ID: 15721262
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.
    Tsuchiya M; Dang N; Kerr EO; Hu D; Steffen KK; Oakes JA; Kennedy BK; Kaeberlein M
    Aging Cell; 2006 Dec; 5(6):505-14. PubMed ID: 17129213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.
    Imai S; Armstrong CM; Kaeberlein M; Guarente L
    Nature; 2000 Feb; 403(6771):795-800. PubMed ID: 10693811
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Diversity in the Sir2 family of protein deacetylases.
    Buck SW; Gallo CM; Smith JS
    J Leukoc Biol; 2004 Jun; 75(6):939-50. PubMed ID: 14742637
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantitative assays for characterization of the Sir2 family of NAD(+)-dependent deacetylases.
    Borra MT; Denu JM
    Methods Enzymol; 2004; 376():171-87. PubMed ID: 14975305
    [No Abstract]   [Full Text] [Related]  

  • 11. Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases.
    Marmorstein R
    Biochem Soc Trans; 2004 Dec; 32(Pt 6):904-9. PubMed ID: 15506920
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates.
    Sauve AA; Schramm VL
    Curr Med Chem; 2004 Apr; 11(7):807-26. PubMed ID: 15078167
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases.
    Khan AN; Lewis PN
    J Biol Chem; 2006 Apr; 281(17):11702-11. PubMed ID: 16520376
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1.
    Bitterman KJ; Anderson RM; Cohen HY; Latorre-Esteves M; Sinclair DA
    J Biol Chem; 2002 Nov; 277(47):45099-107. PubMed ID: 12297502
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The NAD(+)-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication.
    Pappas DL; Frisch R; Weinreich M
    Genes Dev; 2004 Apr; 18(7):769-81. PubMed ID: 15082529
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the histone deacetylase SIRT2.
    Finnin MS; Donigian JR; Pavletich NP
    Nat Struct Biol; 2001 Jul; 8(7):621-5. PubMed ID: 11427894
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Longevity research. Single signal unites treatments that prolong life.
    Strauss E
    Science; 2003 May; 300(5621):881-3. PubMed ID: 12738822
    [No Abstract]   [Full Text] [Related]  

  • 18. The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation.
    Bell SD; Botting CH; Wardleworth BN; Jackson SP; White MF
    Science; 2002 Apr; 296(5565):148-51. PubMed ID: 11935028
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.
    Tanny JC; Kirkpatrick DS; Gerber SA; Gygi SP; Moazed D
    Mol Cell Biol; 2004 Aug; 24(16):6931-46. PubMed ID: 15282295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
    Frye RA
    Biochem Biophys Res Commun; 1999 Jun; 260(1):273-9. PubMed ID: 10381378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.