141 related articles for article (PubMed ID: 15784656)
1. Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
Jacobson PB; von Geldern TW; Ohman L; Osterland M; Wang J; Zinker B; Wilcox D; Nguyen PT; Mika A; Fung S; Fey T; Goos-Nilsson A; Grynfarb M; Barkhem T; Marsh K; Beno DW; Nga-Nguyen B; Kym PR; Link JT; Tu N; Edgerton DS; Cherrington A; Efendic S; Lane BC; Opgenorth TJ
J Pharmacol Exp Ther; 2005 Jul; 314(1):191-200. PubMed ID: 15784656
[TBL] [Abstract][Full Text] [Related]
2. Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance.
Zinker B; Mika A; Nguyen P; Wilcox D; Ohman L; von Geldern TW; Opgenorth T; Jacobson P
Metabolism; 2007 Mar; 56(3):380-7. PubMed ID: 17292727
[TBL] [Abstract][Full Text] [Related]
3. Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators.
Link JT; Sorensen B; Patel J; Grynfarb M; Goos-Nilsson A; Wang J; Fung S; Wilcox D; Zinker B; Nguyen P; Hickman B; Schmidt JM; Swanson S; Tian Z; Reisch TJ; Rotert G; Du J; Lane B; von Geldern TW; Jacobson PB
J Med Chem; 2005 Aug; 48(16):5295-304. PubMed ID: 16078847
[TBL] [Abstract][Full Text] [Related]
4. Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production.
Edgerton DS; Jacobson PB; Opgenorth TJ; Zinker B; Beno D; von Geldern T; Ohman L; Scott M; Neal D; Cherrington AD
Metabolism; 2006 Sep; 55(9):1255-62. PubMed ID: 16919547
[TBL] [Abstract][Full Text] [Related]
5. Blood glucose-lowering nuclear receptor agonists only partially normalize hepatic gene expression in db/db mice.
Loffler M; Bilban M; Reimers M; Waldhäusl W; Stulnig TM
J Pharmacol Exp Ther; 2006 Feb; 316(2):797-804. PubMed ID: 16260581
[TBL] [Abstract][Full Text] [Related]
6. Hepatic dysfunction and insulin insensitivity in type 2 diabetes mellitus: a critical target for insulin-sensitizing agents.
Home PD; Pacini G
Diabetes Obes Metab; 2008 Sep; 10(9):699-718. PubMed ID: 17825080
[TBL] [Abstract][Full Text] [Related]
7. [Glucocorticoid-induced insulin resistance and diabetes mellitus. Receptor-, postreceptor mechanisms, local cortisol action, and new aspects of antidiabetic therapy].
Meyer G; Badenhoop K
Med Klin (Munich); 2003 Apr; 98(5):266-70. PubMed ID: 12721671
[TBL] [Abstract][Full Text] [Related]
8. A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.
Chang CH; McNamara LA; Wu MS; Muise ES; Tan Y; Wood HB; Meinke PT; Thompson JR; Doebber TW; Berger JP; McCann ME
Eur J Pharmacol; 2008 Apr; 584(1):192-201. PubMed ID: 18346728
[TBL] [Abstract][Full Text] [Related]
9. 18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.
Anandharajan R; Sayyed SG; Doshi LS; Dixit P; Chandak PG; Dixit AV; Brahma MK; Deshmukh NJ; Gupte R; Damre A; Suthar J; Padigaru M; Sharma SD; Nemmani KV
Metabolism; 2009 Oct; 58(10):1503-16. PubMed ID: 19608207
[TBL] [Abstract][Full Text] [Related]
10. Gene expression of mineralocorticoid and glucocorticoid receptors in the limbic system is related to type-2 like diabetes in leptin-resistant rats.
Jöhren O; Dendorfer A; Dominiak P; Raasch W
Brain Res; 2007 Dec; 1184():160-7. PubMed ID: 17945204
[TBL] [Abstract][Full Text] [Related]
11. Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice.
Liang Y; Osborne MC; Monia BP; Bhanot S; Watts LM; She P; DeCarlo SO; Chen X; Demarest K
Metabolism; 2005 Jul; 54(7):848-55. PubMed ID: 15988691
[TBL] [Abstract][Full Text] [Related]
12. Hypoglycemic effect of hot-water extract of adzuki (Vigna angularis) in spontaneously diabetic KK-A(y) mice.
Itoh T; Kobayashi M; Horio F; Furuichi Y
Nutrition; 2009 Feb; 25(2):134-41. PubMed ID: 18929464
[TBL] [Abstract][Full Text] [Related]
13. Ameliorating effect of FK614, a novel nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist, on insulin resistance in Zucker fatty rat.
Minoura H; Takeshita S; Yamamoto T; Mabuchi M; Hirosumi J; Takakura S; Kawamura I; Seki J; Manda T; Ita M; Mutoh S
Eur J Pharmacol; 2005 Sep; 519(1-2):182-90. PubMed ID: 16039648
[TBL] [Abstract][Full Text] [Related]
14. Muraglitazar, a novel dual (alpha/gamma) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves beta-cell function in db/db mice.
Harrity T; Farrelly D; Tieman A; Chu C; Kunselman L; Gu L; Ponticiello R; Cap M; Qu F; Shao C; Wang W; Zhang H; Fenderson W; Chen S; Devasthale P; Jeon Y; Seethala R; Yang WP; Ren J; Zhou M; Ryono D; Biller S; Mookhtiar KA; Wetterau J; Gregg R; Cheng PT; Hariharan N
Diabetes; 2006 Jan; 55(1):240-8. PubMed ID: 16380499
[TBL] [Abstract][Full Text] [Related]
15. Comparison of the antidiabetic effects of brain-derived neurotrophic factor and thiazolidinediones in obese diabetic mice.
Yamanaka M; Itakura Y; Tsuchida A; Nakagawa T; Noguchi H; Taiji M
Diabetes Obes Metab; 2007 Nov; 9(6):879-88. PubMed ID: 17924870
[TBL] [Abstract][Full Text] [Related]
16. The role of the liver on post-prandial glycaemia--emphasis on hepatic glucose uptake.
Kawamori R
Int J Clin Pract Suppl; 2000 Sep; (112):19-22. PubMed ID: 11064947
[No Abstract] [Full Text] [Related]
17. Bis(alpha-furancarboxylato)oxovanadium(IV) prevents and improves dexamethasone-induced insulin resistance in 3T3-L1 adipocytes.
Zuo YQ; Liu WP; Niu YF; Tian CF; Xie MJ; Chen XZ; Li L
J Pharm Pharmacol; 2008 Oct; 60(10):1335-40. PubMed ID: 18812026
[TBL] [Abstract][Full Text] [Related]
18. Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.
Hong EG; Jung DY; Ko HJ; Zhang Z; Ma Z; Jun JY; Kim JH; Sumner AD; Vary TC; Gardner TW; Bronson SK; Kim JK
Am J Physiol Endocrinol Metab; 2007 Dec; 293(6):E1687-96. PubMed ID: 17911348
[TBL] [Abstract][Full Text] [Related]
19. Exendin-4 and exercise improve hepatic glucose homeostasis by promoting insulin signaling in diabetic rats.
Park S; Hong SM; Ahn IS
Metabolism; 2010 Jan; 59(1):123-33. PubMed ID: 19766272
[TBL] [Abstract][Full Text] [Related]
20. Halofenate is a selective peroxisome proliferator-activated receptor gamma modulator with antidiabetic activity.
Allen T; Zhang F; Moodie SA; Clemens LE; Smith A; Gregoire F; Bell A; Muscat GE; Gustafson TA
Diabetes; 2006 Sep; 55(9):2523-33. PubMed ID: 16936200
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]