BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

476 related articles for article (PubMed ID: 15784872)

  • 41. Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?
    Zhou H; Li L; Yang P; Yang L; Zheng JE; Zhou Y; Han Y
    BMC Cancer; 2018 May; 18(1):516. PubMed ID: 29720126
    [TBL] [Abstract][Full Text] [Related]  

  • 42. [Therapeutic drug monitoring of 6-thioguanine nucleotides in paediatric acute lymphoblastic leukaemia: interest and limits].
    Fakhoury M; de Beaumais T; Médard Y; Jacqz-Aigrain E;
    Therapie; 2010; 65(3):187-93. PubMed ID: 20699069
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Role of TPMT and ITPA variants in mercaptopurine disposition.
    Gerbek T; Ebbesen M; Nersting J; Frandsen TL; Appell ML; Schmiegelow K
    Cancer Chemother Pharmacol; 2018 Mar; 81(3):579-586. PubMed ID: 29387964
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Thiopurine methyltransferase polymorphisms in a multiracial asian population and children with acute lymphoblastic leukemia.
    Kham SK; Tan PL; Tay AH; Heng CK; Yeoh AE; Quah TC
    J Pediatr Hematol Oncol; 2002; 24(5):353-9. PubMed ID: 12142782
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects.
    Brouwer C; De Abreu RA; Keizer-Garritsen JJ; Lambooy LH; Ament K; ter Riet PG; van Wering ER; Trijbels FJ; Veerman AJ; Hoogerbrugge PM; Bökkerink JP
    Eur J Cancer; 2005 Mar; 41(4):613-23. PubMed ID: 15737567
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment.
    Coulthard SA; Matheson EC; Hall AG; Hogarth LA
    Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1385-91. PubMed ID: 15571264
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations.
    Maillard M; Nishii R; Yang W; Hoshitsuki K; Chepyala D; Lee SHR; Nguyen JQ; Relling MV; Crews KR; Leggas M; Singh M; Suang JLY; Yeoh AEJ; Jeha S; Inaba H; Pui CH; Karol SE; Trehan A; Bhatia P; Antillon Klussmann FG; Bhojwani D; Haidar CE; Yang JJ
    J Natl Cancer Inst; 2024 May; 116(5):702-710. PubMed ID: 38230823
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia.
    Relling MV; Hancock ML; Boyett JM; Pui CH; Evans WE
    Blood; 1999 May; 93(9):2817-23. PubMed ID: 10216075
    [TBL] [Abstract][Full Text] [Related]  

  • 49. [Effect of genetic polymorphism of TPMT and NUDT15 on the tolerance of 6-mercaptopurine therapy in adult acute lymphoblastic leukemia].
    Hao QS; Wang Z; Fang QY; Gong XY; Liu KQ; Li Y; Wei H; Wang Y; Li QH; Wang M; Tian Z; Wang JX; Mi YC
    Zhonghua Xue Ye Xue Za Zhi; 2021 Nov; 42(11):911-916. PubMed ID: 35045652
    [No Abstract]   [Full Text] [Related]  

  • 50. Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model.
    Ramsey LB; Janke LJ; Edick MJ; Cheng C; Williams RT; Sherr CJ; Evans WE; Relling MV
    Pharmacogenet Genomics; 2014 May; 24(5):263-71. PubMed ID: 24710003
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Influence of thiopurine methyltransferase gene polymorphism on Egyptian children with acute lymphoblastic leukaemia.
    Tantawy AAG; Ebeid FSE; Adly AAM; El-Ghoroury E; Mostafa M
    J Genet; 2017 Dec; 96(6):905-910. PubMed ID: 29321348
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Frequency of TPMT alleles in Indian patients with acute lymphatic leukemia and effect on the dose of 6-mercaptopurine.
    Desire S; Balasubramanian P; Bajel A; George B; Viswabandya A; Mathews V; Srivastava A; Chandy M
    Med Oncol; 2010 Dec; 27(4):1046-9. PubMed ID: 19830600
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia.
    Dorababu P; Nagesh N; Linga VG; Gundeti S; Kutala VK; Reddanna P; Digumarti R
    Eur J Clin Pharmacol; 2012 Apr; 68(4):379-87. PubMed ID: 22009189
    [TBL] [Abstract][Full Text] [Related]  

  • 54. [The effect of the adverse events with thiopurine S-methyltransferase gene mutation on outcome of childhood acute lymphoblastic leukemia].
    Cao L; Zhang ZX; Chai YH; Hu SY; Wang Y; Zhao WL; He HL; Lu J
    Zhonghua Xue Ye Xue Za Zhi; 2013 Mar; 34(3):247-52. PubMed ID: 23683426
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate.
    Pettersson B; Almer S; Albertioni F; Söderhäll S; Peterson C
    Ther Drug Monit; 2002 Jun; 24(3):351-8. PubMed ID: 12021625
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia.
    McLeod HL; Relling MV; Liu Q; Pui CH; Evans WE
    Blood; 1995 Apr; 85(7):1897-902. PubMed ID: 7703493
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia.
    Wennerstrand P; Mårtensson LG; Söderhäll S; Zimdahl A; Appell ML
    Eur J Clin Pharmacol; 2013 Sep; 69(9):1641-9. PubMed ID: 23660772
    [TBL] [Abstract][Full Text] [Related]  

  • 58. [New techniques for optimization of thiopurine therapy in leukemia and transplantation].
    Loennechen T; Lysaa RA; Giverhaug T; Sylte I; Mathiesen LE; Aarbakke J
    Tidsskr Nor Laegeforen; 2002 Apr; 122(11):1107-10. PubMed ID: 12043054
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Augmenting clinical interpretability of thiopurine methyltransferase laboratory evaluation.
    Demlova R; Mrkvicova M; Sterba J; Bernatikova H; Stary J; Sukova M; Mikuskova A; Chocholova A; Mladosievicova B; Soltysova A; Behulova D; Pilatova K; Zdrazilova-Dubska L; Valik D
    Oncology; 2014; 86(3):152-8. PubMed ID: 24643197
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Pharmacokinetics of 6-Thioguanine and 6-Mercaptopurine Combination Maintenance Therapy of Childhood ALL: Hypothesis and Case Report.
    Nielsen SN; Frandsen TL; Nersting J; Hjalgrim LL; Schmiegelow K
    J Pediatr Hematol Oncol; 2015 Apr; 37(3):e206-9. PubMed ID: 25171455
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 24.