BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 15789622)

  • 1. Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes.
    Gazi L; Gyles S; Rose J; Lees S; Allan C; Xue L; Jassal R; Speight G; Gamble V; Pettipher R
    Prostaglandins Other Lipid Mediat; 2005 Jan; 75(1-4):153-67. PubMed ID: 15789622
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
    Xue L; Gyles SL; Wettey FR; Gazi L; Townsend E; Hunter MG; Pettipher R
    J Immunol; 2005 Nov; 175(10):6531-6. PubMed ID: 16272307
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats.
    Almishri W; Cossette C; Rokach J; Martin JG; Hamid Q; Powell WS
    J Pharmacol Exp Ther; 2005 Apr; 313(1):64-9. PubMed ID: 15590767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils.
    Pettipher R; Vinall SL; Xue L; Speight G; Townsend ER; Gazi L; Whelan CJ; Armer RE; Payton MA; Hunter MG
    J Pharmacol Exp Ther; 2012 Feb; 340(2):473-82. PubMed ID: 22106101
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2.
    Hirai H; Tanaka K; Yoshie O; Ogawa K; Kenmotsu K; Takamori Y; Ichimasa M; Sugamura K; Nakamura M; Takano S; Nagata K
    J Exp Med; 2001 Jan; 193(2):255-61. PubMed ID: 11208866
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.
    Sykes DA; Bradley ME; Riddy DM; Willard E; Reilly J; Miah A; Bauer C; Watson SJ; Sandham DA; Dubois G; Charlton SJ
    Mol Pharmacol; 2016 May; 89(5):593-605. PubMed ID: 26916831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.
    Yoshimura-Uchiyama C; Iikura M; Yamaguchi M; Nagase H; Ishii A; Matsushima K; Yamamoto K; Shichijo M; Bacon KB; Hirai K
    Clin Exp Allergy; 2004 Aug; 34(8):1283-90. PubMed ID: 15298571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils.
    Böhm E; Sturm GJ; Weiglhofer I; Sandig H; Shichijo M; McNamee A; Pease JE; Kollroser M; Peskar BA; Heinemann A
    J Biol Chem; 2004 Feb; 279(9):7663-70. PubMed ID: 14668348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.
    Schratl P; Royer JF; Kostenis E; Ulven T; Sturm EM; Waldhoer M; Hoefler G; Schuligoi R; Lippe IT; Peskar BA; Heinemann A
    J Immunol; 2007 Oct; 179(7):4792-9. PubMed ID: 17878378
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils.
    Monneret G; Cossette C; Gravel S; Rokach J; Powell WS
    J Pharmacol Exp Ther; 2003 Jan; 304(1):349-55. PubMed ID: 12490611
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats.
    Shichijo M; Sugimoto H; Nagao K; Inbe H; Encinas JA; Takeshita K; Bacon KB; Gantner F
    J Pharmacol Exp Ther; 2003 Nov; 307(2):518-25. PubMed ID: 12975488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants.
    Gyles SL; Xue L; Townsend ER; Wettey F; Pettipher R
    Immunology; 2006 Nov; 119(3):362-8. PubMed ID: 17067313
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration.
    Chiba T; Ueki S; Ito W; Kato H; Kamada R; Takeda M; Kayaba H; Furue M; Chihara J
    Ann Allergy Asthma Immunol; 2011 Jun; 106(6):511-7. PubMed ID: 21624751
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.
    Schuligoi R; Sedej M; Waldhoer M; Vukoja A; Sturm EM; Lippe IT; Peskar BA; Heinemann A
    J Leukoc Biol; 2009 Jan; 85(1):136-45. PubMed ID: 18835884
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Agonist and antagonist effects of 15R-prostaglandin (PG) D2 and 11-methylene-PGD2 on human eosinophils and basophils.
    Cossette C; Walsh SE; Kim S; Lee GJ; Lawson JA; Bellone S; Rokach J; Powell WS
    J Pharmacol Exp Ther; 2007 Jan; 320(1):173-9. PubMed ID: 17041009
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2.
    Mimura H; Ikemura T; Kotera O; Sawada M; Tashiro S; Fuse E; Ueno K; Manabe H; Ohshima E; Karasawa A; Miyaji H
    J Pharmacol Exp Ther; 2005 Jul; 314(1):244-51. PubMed ID: 15798001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.
    Sugimoto H; Shichijo M; Okano M; Bacon KB
    Eur J Pharmacol; 2005 Nov; 524(1-3):30-7. PubMed ID: 16256979
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prostaglandin D
    Carstensen S; Gress C; Erpenbeck VJ; Kazani SD; Hohlfeld JM; Sandham DA; Müller M
    Respir Res; 2021 Oct; 22(1):262. PubMed ID: 34620168
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2).
    Xue L; Gyles SL; Barrow A; Pettipher R
    Biochem Pharmacol; 2007 Mar; 73(6):843-53. PubMed ID: 17196174
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy.
    Calbet M; Andrés M; Armengol C; Bravo M; Eichhorn P; López R; García-González V; Roberts R; Miralpeix M
    Pharmacol Res; 2016 Sep; 111():208-216. PubMed ID: 27317944
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.