245 related articles for article (PubMed ID: 15798097)
1. Pim-1 kinase stability is regulated by heat shock proteins and the ubiquitin-proteasome pathway.
Shay KP; Wang Z; Xing PX; McKenzie IF; Magnuson NS
Mol Cancer Res; 2005 Mar; 3(3):170-81. PubMed ID: 15798097
[TBL] [Abstract][Full Text] [Related]
2. Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.
Powers MV; Clarke PA; Workman P
Cancer Cell; 2008 Sep; 14(3):250-62. PubMed ID: 18772114
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
[TBL] [Abstract][Full Text] [Related]
4. Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells.
Kim HR; Kang HS; Kim HD
IUBMB Life; 1999 Oct; 48(4):429-33. PubMed ID: 10632574
[TBL] [Abstract][Full Text] [Related]
5. CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins.
Doong H; Rizzo K; Fang S; Kulpa V; Weissman AM; Kohn EC
J Biol Chem; 2003 Aug; 278(31):28490-500. PubMed ID: 12750378
[TBL] [Abstract][Full Text] [Related]
6. Geldanamycin and its analogue 17-allylamino-17-demethoxygeldanamycin lowers Bcr-Abl levels and induces apoptosis and differentiation of Bcr-Abl-positive human leukemic blasts.
Nimmanapalli R; O'Bryan E; Bhalla K
Cancer Res; 2001 Mar; 61(5):1799-804. PubMed ID: 11280726
[TBL] [Abstract][Full Text] [Related]
7. Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.
Mimnaugh EG; Xu W; Vos M; Yuan X; Isaacs JS; Bisht KS; Gius D; Neckers L
Mol Cancer Ther; 2004 May; 3(5):551-66. PubMed ID: 15141013
[TBL] [Abstract][Full Text] [Related]
8. Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein.
Bonvini P; Dalla Rosa H; Vignes N; Rosolen A
Cancer Res; 2004 May; 64(9):3256-64. PubMed ID: 15126367
[TBL] [Abstract][Full Text] [Related]
9. Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK).
Qing G; Yan P; Xiao G
Cell Res; 2006 Nov; 16(11):895-901. PubMed ID: 17088896
[TBL] [Abstract][Full Text] [Related]
10. Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B.
Hashiramoto A; Murata M; Kawazoe T; Yoshida K; Akiyama C; Shiozawa K; Shiozawa S
Rheumatology (Oxford); 2011 May; 50(5):852-61. PubMed ID: 21177334
[TBL] [Abstract][Full Text] [Related]
11. Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.
Guo F; Rocha K; Bali P; Pranpat M; Fiskus W; Boyapalle S; Kumaraswamy S; Balasis M; Greedy B; Armitage ES; Lawrence N; Bhalla K
Cancer Res; 2005 Nov; 65(22):10536-44. PubMed ID: 16288046
[TBL] [Abstract][Full Text] [Related]
12. Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation.
Yun BG; Matts RL
Exp Cell Res; 2005 Jul; 307(1):212-23. PubMed ID: 15922741
[TBL] [Abstract][Full Text] [Related]
13. Regulation of Pim-1 by Hsp90.
Mizuno K; Shirogane T; Shinohara A; Iwamatsu A; Hibi M; Hirano T
Biochem Biophys Res Commun; 2001 Mar; 281(3):663-9. PubMed ID: 11237709
[TBL] [Abstract][Full Text] [Related]
14. The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Lilly M; Sandholm J; Cooper JJ; Koskinen PJ; Kraft A
Oncogene; 1999 Jul; 18(27):4022-31. PubMed ID: 10435626
[TBL] [Abstract][Full Text] [Related]
15. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
Fujiwara H; Yamakuni T; Ueno M; Ishizuka M; Shinkawa T; Isobe T; Ohizumi Y
J Pharmacol Exp Ther; 2004 Sep; 310(3):1288-95. PubMed ID: 15161934
[TBL] [Abstract][Full Text] [Related]
16. Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor beta-activated kinase 1 (TAK1) in interleukin-1beta-induced cell signaling.
Shi L; Zhang Z; Fang S; Xu J; Liu J; Shen J; Fang F; Luo L; Yin Z
Mol Immunol; 2009 Feb; 46(4):541-50. PubMed ID: 18950863
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of Hsp90 function delays and impairs recovery from heat shock.
Duncan RF
FEBS J; 2005 Oct; 272(20):5244-56. PubMed ID: 16218955
[TBL] [Abstract][Full Text] [Related]
18. Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells.
Yoshikawa N; Nemoto T; Satoh S; Maruta T; Yanagita T; Chosa E; Wada A
Neurochem Int; 2010 Jan; 56(1):42-50. PubMed ID: 19737590
[TBL] [Abstract][Full Text] [Related]
19. The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome.
An WG; Schulte TW; Neckers LM
Cell Growth Differ; 2000 Jul; 11(7):355-60. PubMed ID: 10939589
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
Srethapakdi M; Liu F; Tavorath R; Rosen N
Cancer Res; 2000 Jul; 60(14):3940-6. PubMed ID: 10919672
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]